The LabelHash Server and Tools for Substructure-Based Functional Annotation

Publication Type:

Journal Article

Authors:

Moll, Mark; Bryant, Drew H; Lydia E. Kavraki

Source:

Bioinformatics, Volume 27, Number 15, p.2161--2162 (2011)

Keywords:

kavrakilab, protein function

Abstract:

Summary: The LabelHash server and tools are designed for large- scale substructure comparison. The main use is to predict the function of unknown proteins. Given a set of (putative) functional residues, LabelHash finds all occurrences of matching substructures in the entire Protein Data Bank, along with a statistical significance estimate and known functional annotations for each match. The results can be downloaded for further analysis in any molecular viewer. For Chimera there is a plugin to facilitate this process. Availability: The website is free and open to all users with no login requirements at http://labelhash.kavrakilab.org.


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