The LabelHash Server
8tlnE motif
Motif residues: MET120 GLU143 LEU144 TYR157 HIS231
Table of Top 100 matches
Click here for a compact table with the top 100 matches.The images below show the motif residues and the match residues superimposed. The carbon atoms are white in the motif and green in the match. Other atoms in the motif and match are colored by element. The C-alphas are shown as spheres, while the remaining motif and match atoms are shown in stick representation. The rest of the matching protein is shown in ribbon representation.
Downloads
- A zip file with PDB files for the top 100 matches and the motif itself.
- An XML file with all matches. You can open this file in Chimera with our ViewMatch plugin.
Top 20 matches
For each match you can click on the "[pdb]" link to download a PDB file with the matching chain aligned with the motif.1. 3tliA [pdb]
LRMSD: 0.18561732769p-value: 2.69184656645e-05
Matching residues: MET120 GLU143 LEU144 TYR157 HIS231
EC class: 3.4.24.27
GO terms:
Molecular function: metal ion binding, hydrolase activity, zinc ion binding, metallopeptidase activity, peptidase activity, calcium ion binding, metalloendopeptidase activity
Biological process: proteolysis
Cellular component: extracellular region
2. 1bqbA [pdb]
LRMSD: 0.23453322053p-value: 5.69676521991e-05
Matching residues: MET122 GLU145 ILE146 TYR159 HIS228
EC class: 3.4.24.29
GO terms:
Molecular function: metal ion binding, hydrolase activity, zinc ion binding, metallopeptidase activity, peptidase activity, calcium ion binding, metalloendopeptidase activity
Biological process: proteolysis
Cellular component: extracellular region
3. 2bh2B [pdb]
LRMSD: 0.416725605726p-value: 0.000124924394186
Matching residues: SER117 MET416 LEU423 GLU424 LEU428
EC class: GO terms:
Molecular function: 4 iron, 4 sulfur cluster binding, iron-sulfur cluster binding, metal ion binding, transferase activity, methyltransferase activity, iron ion binding, RNA methyltransferase activity, RNA binding, S-adenosylmethionine-dependent methyltransferase activity
Biological process: rRNA processing, RNA processing
4. 1u4gA [pdb]
LRMSD: 0.45767429471p-value: 0.000170465878909
Matching residues: MET120 GLU141 VAL142 TYR155 HIS223
EC class: 3.4.24.26
GO terms:
Molecular function: metal ion binding, hydrolase activity, zinc ion binding, metallopeptidase activity, peptidase activity, calcium ion binding, metalloendopeptidase activity
Biological process: proteolysis
Cellular component: extracellular region
5. 3bjqH [pdb]
LRMSD: 0.468884646893p-value: 0.00017836803454
Matching residues: LEU28 ALA119 LEU120 TYR266 HIS271
EC class: 0.0.0.0
GO terms:
6. 2pz9A [pdb]
LRMSD: 0.539235532284p-value: 0.000273494719295
Matching residues: LEU89 LEU95 ILE175 ALA176 LEU205
EC class: 0.0.0.0
GO terms:
Molecular function: DNA binding, transcription factor activity
Biological process: regulation of transcription, DNA-dependent, transcription, regulation of transcription
7. 2nn6B [pdb]
LRMSD: 0.545391023159p-value: 0.000283064437099
Matching residues: LEU100 TYR134 LEU189 ILE195 ALA196
EC class: GO terms:
Molecular function: protein binding, RNA binding, hydrolase activity, exonuclease activity, nuclease activity, protein binding, 3'-5'-exoribonuclease activity, hydrolase activity, exonuclease activity, nuclease activity, RNA binding, hydrolase activity, exonuclease activity, nuclease activity, RNA binding, 7S RNA binding, 3'-5'-exoribonuclease activity, protein binding, molecular_function, hydrolase activity, exonuclease activity, nuclease activity, RNA binding, 3'-5'-exoribonuclease activity, identical protein binding, protein binding, protein binding, RNA binding, 3'-5'-exoribonuclease activity, hydrolase activity, exonuclease activity, nuclease activity, 3'-5'-exoribonuclease activity, hydrolase activity, exonuclease activity, nuclease activity, RNA binding, protein binding, RNA binding, 3'-5'-exoribonuclease activity, hydrolase activity, exonuclease activity, nuclease activity, protein binding, 3'-5'-exoribonuclease activity, hydrolase activity, exonuclease activity, nuclease activity, RNA binding, protein binding, hydrolase activity, exonuclease activity, nuclease activity, RNA binding, 3'-5'-exoribonuclease activity
Biological process: rRNA processing, rRNA processing, RNA processing, rRNA processing, biological_process, rRNA processing, RNA processing, RNA catabolic process, rRNA processing, RNA processing, rRNA processing, RNA processing, immune response, rRNA processing, RNA processing, rRNA processing, rRNA processing, RNA processing
Cellular component: exosome (RNase complex), nucleolus, nucleus, nucleolus, cytoplasm, nucleus, exosome (RNase complex), cytoplasm, nucleus, exosome (RNase complex), cellular_component, cytoplasm, nucleus, exosome (RNase complex), nucleolus, nucleolus, nucleolus, nucleolus, nucleolus, exosome (RNase complex), nucleus, cytoplasm, nucleolus, nucleus, exosome (RNase complex), nuclear exosome (RNase complex), cytoplasm, nucleus, exosome (RNase complex), nucleolus, cytoplasmic exosome (RNase complex), nuclear exosome (RNase complex), cytoplasm, nucleus, exosome (RNase complex), cytoplasm, nucleus, exosome (RNase complex)
8. 1x3fA [pdb]
LRMSD: 0.59966313839p-value: 0.000389715918573
Matching residues: LEU13 SER35 LEU83 VAL99 GLU100
EC class: GO terms:
Molecular function: DNA binding, single-stranded DNA binding
Biological process: response to DNA damage stimulus, DNA repair, DNA replication
9. 2rjqA [pdb]
LRMSD: 0.614951729774p-value: 0.000432497879956
Matching residues: LEU301 HIS310 ALA314 VAL315 LEU481
EC class: 0.0.0.0
GO terms:
Molecular function: metal ion binding, hydrolase activity, zinc ion binding, metallopeptidase activity, peptidase activity, integrin binding, metalloendopeptidase activity
Biological process: proteolysis
Cellular component: plasma membrane, cytoplasm, nucleus, proteinaceous extracellular matrix, extracellular region, extracellular matrix
10. 3cwbC [pdb]
LRMSD: 0.63046246767p-value: 0.000518550921697
Matching residues: LEU282 LEU293 ALA294 LEU302 LEU364
EC class: 0.0.0.0
GO terms:
Molecular function: oxidoreductase activity, acting on diphenols and related substances as donors, 2 iron, 2 sulfur cluster binding, iron-sulfur cluster binding, metal ion binding, oxidoreductase activity, ubiquinol-cytochrome-c reductase activity, electron carrier activity, iron ion binding, metal ion binding, iron ion binding, oxidoreductase activity, electron carrier activity
Biological process: oxidation reduction, electron transport chain, transport, electron transport chain, transport, respiratory electron transport chain
Cellular component: respiratory chain, membrane fraction, respiratory chain, mitochondrial inner membrane, integral to membrane, membrane, mitochondrial respiratory chain, mitochondrion, mitochondrial inner membrane, integral to membrane, membrane, mitochondrial respiratory chain, mitochondrion
11. 1hdsD [pdb]
LRMSD: 0.643120706081p-value: 0.000555045262445
Matching residues: LEU80 LEU90 VAL136 ALA139 HIS145
EC class: GO terms:
Molecular function: metal ion binding, iron ion binding, oxygen transporter activity, heme binding, oxygen binding, metal ion binding, iron ion binding, oxygen transporter activity, heme binding, oxygen binding
Biological process: oxygen transport, transport, oxygen transport, transport
Cellular component: hemoglobin complex, hemoglobin complex
12. 3fi1A [pdb]
LRMSD: 0.649189174175p-value: 0.000595785037149
Matching residues: ILE134 ALA135 LEU138 LEU255 LEU262
EC class: GO terms:
Molecular function: sodium ion binding, antiporter activity, sodium ion transmembrane transporter activity
Biological process: sodium ion transport, ion transport, transport, regulation of pH
Cellular component: plasma membrane, integral to membrane, membrane
13. 1xbaA [pdb]
LRMSD: 0.651230990887p-value: 0.000641252205241
Matching residues: LEU453 LEU495 ALA497 TYR507 LEU561
EC class: 2.7.10.2
GO terms:
Molecular function: integrin binding, protein kinase activity, transferase activity, kinase activity, ATP binding, protein tyrosine kinase activity, nucleotide binding, non-membrane spanning protein tyrosine kinase activity, protein binding, receptor signaling protein tyrosine kinase activity
Biological process: neutrophil chemotaxis, leukocyte adhesion, integrin-mediated signaling pathway, interspecies interaction between organisms, cell proliferation, organ morphogenesis, protein amino acid phosphorylation, protein complex assembly, signal transduction, B cell receptor signaling pathway, positive regulation of calcium-mediated signaling, positive regulation of peptidyl-tyrosine phosphorylation, protein amino acid autophosphorylation, positive regulation of alpha-beta T cell proliferation, positive regulation of alpha-beta T cell differentiation, positive regulation of gamma-delta T cell differentiation, positive regulation of B cell differentiation, positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, positive regulation of interleukin-3 biosynthetic process, beta selection, positive regulation of mast cell degranulation, leukotriene biosynthetic process, peptidyl-tyrosine phosphorylation, activation of JUN kinase activity, intracellular signaling cascade, enzyme linked receptor protein signaling pathway, cell surface receptor linked signal transduction, serotonin secretion, activation of MAPK activity
Cellular component: intracellular membrane-bounded organelle, cytoplasm, nucleolus, nucleus, plasma membrane, T cell receptor complex, B cell receptor complex
14. 1ue1B [pdb]
LRMSD: 0.668816685677p-value: 0.000746475823689
Matching residues: LEU13 SER35 LEU83 ILE99 GLU100
EC class: GO terms:
Molecular function: DNA binding, single-stranded DNA binding
Biological process: response to DNA damage stimulus, DNA repair, DNA replication
15. 2o5vA [pdb]
LRMSD: 0.669381380081p-value: 0.000746508012526
Matching residues: LEU123 LEU200 LEU253 ALA281 LEU285
EC class: GO terms:
Molecular function: ATP binding, DNA binding, nucleotide binding, nucleoside-triphosphatase activity, single-stranded DNA binding
Biological process: SOS response, response to DNA damage stimulus, DNA repair, DNA replication
Cellular component: cytoplasm, chromosome
16. 1s9cB [pdb]
LRMSD: 0.675719022751p-value: 0.000803475908469
Matching residues: LEU106 ALA110 VAL111 MET126 LEU136
EC class: 1.1.1.35, 4.2.1.107
GO terms:
Molecular function: protein binding, isomerase activity, lyase activity, oxidoreductase activity, 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity, 3-hydroxyacyl-CoA dehydrogenase activity, hydro-lyase activity, sterol transporter activity, sterol carrier activity, estradiol 17-beta-dehydrogenase activity, binding, catalytic activity
Biological process: fatty acid beta-oxidation, oxidation reduction, fatty acid metabolic process, lipid metabolic process, metabolic process, very-long-chain fatty acid metabolic process, Sertoli cell development
Cellular component: peroxisome, peroxisomal matrix, mitochondrion
17. 1dtzA [pdb]
LRMSD: 0.67923438549p-value: 0.000866479647812
Matching residues: LEU63 GLU80 VAL81 LEU308 LEU320
EC class: GO terms:
Molecular function: metal ion binding, hydrolase activity, serine-type peptidase activity, peptidase activity, iron ion binding, ferric iron binding
Biological process: iron ion transport, ion transport, transport, cellular iron ion homeostasis
Cellular component: extracellular region
18. 1vpvB [pdb]
LRMSD: 0.688878595829p-value: 0.000936515571084
Matching residues: LEU95 LEU120 ALA121 TYR163 HIS236
EC class: GO terms:
19. 3c7jB [pdb]
LRMSD: 0.699336349964p-value: 0.00109710951801
Matching residues: HIS22 GLU29 LEU32 SER59 LEU70
EC class: 0.0.0.0
GO terms:
Molecular function: DNA binding, transcription factor activity, DNA binding, transcription factor activity
Biological process: regulation of transcription, DNA-dependent, transcription, regulation of transcription, regulation of transcription, regulation of transcription, DNA-dependent, transcription
Cellular component: intracellular, intracellular
