The LabelHash Server

Top 100 matches

For each match you can click on the "[pdb]" link to download a PDB file with the matching chain aligned with the motif.
Download a zip file with PDB files for all the matches and the motif itself.

PDB ID	LRMSD / p-value	Matching Residues	EC	Gene Ontology annotations
3b54B	[pdb]	1.22993 9.26107e-05	13^LYS 14^PRO 93^GLY 106^ARG 116^ASN 120^GLY	2.7.4.6	metal ion binding transferase activity kinase activity ATP binding magnesium ion binding nucleotide binding nucleoside diphosphate kinase activity protein binding identical protein binding	mitochondrial intermembrane space cytoplasm mitochondrion cytosol	nucleotide metabolic process nucleoside triphosphate biosynthetic process response to DNA damage stimulus nucleoside diphosphate phosphorylation CTP biosynthetic process UTP biosynthetic process GTP biosynthetic process DNA repair
1ndlC	[pdb]	1.32392 0.000297675	13^LYS 14^PRO 93^GLY 106^ARG 116^ASN 120^GLY	2.7.4.6	CTP biosynthetic process UTP biosynthetic process GTP biosynthetic process nucleotide metabolic process protein amino acid autophosphorylation peptidyl-serine phosphorylation epithelial cell migration open tracheal system open tracheal system development mitosis microtubule-based process protein amino acid phosphorylation nucleoside diphosphate phosphorylation	kinase activity magnesium ion binding ATP binding nucleoside diphosphate kinase activity metal ion binding transferase activity nucleotide binding microtubule binding GTP binding	nuclear microtubule cytoplasm microtubule cytoskeleton
1zs6D	[pdb]	1.3331 0.000335478	29^LYS 30^PRO 109^GLY 122^ARG 132^ASN 136^GLY	2.7.4.6	cytosol	metal ion binding transferase activity kinase activity ATP binding magnesium ion binding nucleotide binding nucleoside diphosphate kinase activity	nucleotide metabolic process apoptosis induction of apoptosis CTP biosynthetic process UTP biosynthetic process GTP biosynthetic process
3bbcF	[pdb]	1.33765 0.000355157	12^LYS 13^PRO 92^GLY 105^ARG 115^ASN 119^GLY	2.7.4.6	nucleus cytoplasm lamellipodium ruffle	regulation of transcription regulation of transcription DNA-dependent nucleoside triphosphate biosynthetic process negative regulation of cell proliferation negative regulation of cell cycle nucleotide metabolic process cell cycle transcription CTP biosynthetic process UTP biosynthetic process GTP biosynthetic process positive regulation of epithelial cell proliferation regulation of epidermis development positive regulation of keratinocyte differentiation negative regulation of apoptosis cell adhesion	transcription factor activity ATP binding nucleoside diphosphate kinase activity metal ion binding transferase activity kinase activity DNA binding magnesium ion binding nucleotide binding protein binding
1w7wF	[pdb]	1.33818 0.000355168	11^LYS 12^PRO 91^GLY 104^ARG 114^ASN 118^GLY	0.0.0.0		CTP biosynthetic process UTP biosynthetic process GTP biosynthetic process	transferase activity kinase activity nucleoside diphosphate kinase activity ATP binding nucleotide binding
1sp3A	[pdb]	1.34761 0.000375401	70^ASN 73^ARG 114^GLY 348^PRO 349^LYS 352^GLY	0.0.0.0
1xiqB	[pdb]	1.34884 0.000375426	9^LYS 10^PRO 89^GLY 102^ARG 112^ASN 116^GLY	0.0.0.0		CTP biosynthetic process UTP biosynthetic process GTP biosynthetic process	transferase activity kinase activity ATP binding nucleoside diphosphate kinase activity nucleotide binding
1nclA	[pdb]	1.35734 0.000416674	16^LYS 17^PRO 96^GLY 109^ARG 119^ASN 123^GLY	2.7.4.6	cytoplasm	metal ion binding transferase activity kinase activity ATP binding magnesium ion binding nucleotide binding nucleoside diphosphate kinase activity	nucleotide metabolic process CTP biosynthetic process UTP biosynthetic process GTP biosynthetic process
1u8wB	[pdb]	1.36178 0.000416767	9^LYS 10^PRO 89^GLY 102^ARG 112^ASN 116^GLY	2.7.4.6	apoplast chloroplast plasma membrane vacuole	metal ion binding transferase activity kinase activity ATP binding magnesium ion binding nucleotide binding nucleoside diphosphate kinase activity	response to cadmium ion response to salt stress nucleotide metabolic process CTP biosynthetic process UTP biosynthetic process GTP biosynthetic process
1nb2A	[pdb]	1.36494 0.000437622	10^LYS 11^PRO 90^GLY 103^ARG 113^ASN 117^GLY	0.0.0.0		ATP binding nucleoside diphosphate kinase activity	CTP biosynthetic process UTP biosynthetic process GTP biosynthetic process
2vu5A	[pdb]	1.36918 0.000458789	9^LYS 10^PRO 89^GLY 102^ARG 112^ASN 116^GLY	0.0.0.0	cytoplasm	metal ion binding transferase activity kinase activity ATP binding magnesium ion binding nucleotide binding nucleoside diphosphate kinase activity	nucleotide metabolic process CTP biosynthetic process UTP biosynthetic process GTP biosynthetic process
1bhnE	[pdb]	1.37092 0.000458827	12^LYS 13^PRO 92^GLY 105^ARG 115^ASN 119^GLY	2.7.4.6	metal ion binding transferase activity kinase activity ATP binding magnesium ion binding nucleotide binding nucleoside diphosphate kinase activity protein binding	nucleotide metabolic process CTP biosynthetic process UTP biosynthetic process GTP biosynthetic process endocytosis nervous system development cell differentiation	plasma membrane cytoplasm membrane nucleus mitochondrion
1wklB	[pdb]	1.37675 0.000480258	9^LYS 10^PRO 89^GLY 102^ARG 112^ASN 116^GLY	2.7.4.6	cytoplasm	metal ion binding transferase activity kinase activity ATP binding magnesium ion binding nucleotide binding nucleoside diphosphate kinase activity	nucleotide metabolic process CTP biosynthetic process UTP biosynthetic process GTP biosynthetic process
2hveB	[pdb]	1.39206 0.000523656	12^LYS 13^PRO 92^GLY 105^ARG 115^ASN 119^GLY	2.7.4.6	cytoplasm nucleus	positive regulation of DNA binding regulation of apoptosis negative regulation of cell proliferation negative regulation of cell cycle nucleotide metabolic process cell cycle CTP biosynthetic process UTP biosynthetic process positive regulation of epithelial cell proliferation endocytosis nervous system development cell differentiation GTP biosynthetic process	protein binding GTP binding magnesium ion binding DNA binding deoxyribonuclease activity ATP binding nucleoside diphosphate kinase activity metal ion binding transferase activity kinase activity nucleotide binding identical protein binding
2az3E	[pdb]	1.41167 0.000610362	13^LYS 14^PRO 93^GLY 106^ARG 116^ASN 120^GLY	2.7.4.6	cytoplasm	metal ion binding transferase activity kinase activity ATP binding magnesium ion binding nucleotide binding nucleoside diphosphate kinase activity	nucleotide metabolic process CTP biosynthetic process UTP biosynthetic process GTP biosynthetic process
1pkuD	[pdb]	1.45039 0.000735482	12^LYS 13^PRO 92^GLY 105^ARG 115^ASN 119^GLY	2.7.4.6		metal ion binding transferase activity kinase activity ATP binding magnesium ion binding nucleotide binding nucleoside diphosphate kinase activity	nucleotide metabolic process CTP biosynthetic process UTP biosynthetic process GTP biosynthetic process
1s57A	[pdb]	1.464 0.000774397	91^LYS 92^PRO 171^GLY 184^ARG 194^ASN 198^GLY	2.7.4.6	chloroplast envelope thylakoid chloroplast stroma chloroplast cytoplasm nucleus plastid	protein binding nucleoside diphosphate kinase activity metal ion binding transferase activity kinase activity ATP binding magnesium ion binding identical protein binding nucleotide binding	response to hydrogen peroxide auxin mediated signaling pathway red far-red light phototransduction response to UV nucleotide metabolic process CTP biosynthetic process UTP biosynthetic process GTP biosynthetic process
2nckL	[pdb]	1.46738 0.000774461	11^LYS 12^PRO 91^GLY 104^ARG 114^ASN 118^GLY	2.7.4.6	cytoplasm	metal ion binding transferase activity kinase activity ATP binding magnesium ion binding nucleotide binding nucleoside diphosphate kinase activity	nucleotide metabolic process CTP biosynthetic process UTP biosynthetic process GTP biosynthetic process
2hurC	[pdb]	1.50378 0.000881242	11^LYS 12^PRO 91^GLY 104^ARG 114^ASN 118^GLY	2.7.4.6	cytoplasm	metal ion binding transferase activity kinase activity ATP binding magnesium ion binding nucleotide binding nucleoside diphosphate kinase activity protein binding	nucleotide metabolic process CTP biosynthetic process UTP biosynthetic process GTP biosynthetic process
2ha1A	[pdb]	1.50688 0.000897123	16^ASN 62^GLY 64^LYS 65^PRO 141^GLY 143^ARG		ER-Golgi intermediate compartment proteinaceous extracellular matrix extracellular region platelet alpha granule lumen fibrinogen complex	collagen binding protein binding extracellular matrix structural constituent heparin binding	transmembrane receptor protein tyrosine kinase signaling pathway response to wounding cell migration cell adhesion regulation of cell shape acute-phase response peptide cross-linking substrate adhesion-dependent cell spreading
1k44B	[pdb]	1.52194 0.000927676	10^LYS 11^PRO 90^GLY 104^ARG 114^ASN 118^GLY	2.7.4.6	cytoplasm	metal ion binding transferase activity kinase activity ATP binding magnesium ion binding nucleotide binding nucleoside diphosphate kinase activity	nucleotide metabolic process CTP biosynthetic process UTP biosynthetic process GTP biosynthetic process
2d3aH	[pdb]	1.62496 0.00112791	237^LYS 238^PRO 244^ASN 247^GLY 295^ARG 312^GLY	6.3.1.2	cytoplasm	nitrogen compound metabolic process glutamine biosynthetic process	nucleotide binding ATP binding ligase activity glutamate-ammonia ligase activity catalytic activity
2vf7B	[pdb]	1.65178 0.00116635	620^PRO 623^LYS 626^GLY 628^ASN 631^ARG 638^GLY	0.0.0.0	SOS response response to DNA damage stimulus DNA repair nucleotide-excision repair	cytoplasm excinuclease repair complex	metal ion binding zinc ion binding ATP binding nuclease activity DNA binding nucleotide binding ATPase activity excinuclease ABC activity
2v8oA	[pdb]	1.6617 0.00118555	396^PRO 399^LYS 417^ASN 419^GLY 461^ARG 463^GLY	2.7.7.48, 3.4.21.91	membrane viral envelope viral capsid viral nucleocapsid virion integral to membrane virion part	methylation transcription RNA-dependent viral genome replication viral infectious cycle RNA metabolic process viral reproduction	methyltransferase activity hydrolase activity nucleotidyltransferase activity transferase activity ATP binding structural molecule activity helicase activity RNA-directed RNA polymerase activity nucleotide binding ATP-dependent helicase activity serine-type endopeptidase activity catalytic activity double-stranded RNA binding RNA helicase activity RNA binding nucleic acid binding
1ud1C	[pdb]	1.77859 0.00142068	77^GLY 79^GLY 116^ASN 118^ARG 247^LYS 248^PRO				nutrient reservoir activity
1llwA	[pdb]	1.79025 0.0014384	1376^ASN 1378^ARG 1398^GLY 1414^GLY 1475^PRO 1476^LYS	1.4.7.1		metabolic process nitrogen compound metabolic process glutamate biosynthetic process cellular amino acid biosynthetic process glutamine metabolic process oxidation reduction	oxidoreductase activity glutamate synthase activity catalytic activity protein binding 3 iron 4 sulfur cluster binding iron-sulfur cluster binding metal ion binding iron ion binding glutamate synthase (ferredoxin) activity
3blvG	[pdb]	1.79274 0.00145683	129^VAL 131^LEU 134^ILE 157^ILE 158^LYS 240^SER	0.0.0.0	metal ion binding manganese ion binding oxidoreductase activity catalytic activity RNA binding magnesium ion binding isocitrate dehydrogenase (NAD+) activity oxidoreductase activity acting on the CH-OH group of donors NAD or NADP as acceptor protein binding metal ion binding manganese ion binding oxidoreductase activity catalytic activity RNA binding magnesium ion binding isocitrate dehydrogenase (NAD+) activity protein binding oxidoreductase activity acting on the CH-OH group of donors NAD or NADP as acceptor NAD or NADH binding NAD or NADH binding	mitochondrion mitochondrial isocitrate dehydrogenase complex (NAD+) mitochondrial matrix mitochondrion mitochondrial nucleoid mitochondrial isocitrate dehydrogenase complex (NAD+) mitochondrial matrix	oxidation reduction tricarboxylic acid cycle glutamate biosynthetic process isocitrate metabolic process metabolic process oxidation reduction tricarboxylic acid cycle glutamate biosynthetic process isocitrate metabolic process metabolic process
1wfiA	[pdb]	1.80341 0.00149517	1^GLY 7^GLY 9^ASN 11^ARG 106^LYS 109^PRO		cell division mitosis cell cycle	nucleus microtubule cytoskeleton cytoplasm	protein binding
1po0A	[pdb]	1.81028 0.0015156	86^GLY 348^PRO 353^LYS 355^ASN 390^ARG 407^GLY		cell outer membrane membrane plasma membrane outer membrane	iron ion binding receptor activity siderophore-iron transmembrane transporter activity transporter activity	iron ion transport ion transport transport siderophore transport
1zkmC	[pdb]	1.81688 0.0015371	37^GLY 67^ASN 70^ARG 82^PRO 83^LYS 191^GLY			nucleotidyltransferase activity transferase activity binding catalytic activity	thiamin biosynthetic process metabolic process
3ffjB	[pdb]	1.83891 0.0016087	59^GLY 61^ASN 63^ARG 64^GLY 433^LYS 436^PRO	0.0.0.0		carbohydrate metabolic process	hydrolase activity hydrolyzing O-glycosyl compounds
2h9uA	[pdb]	1.88292 0.00181707	12^GLY 14^LYS 15^PRO 41^GLY 42^ARG 43^ASN	0.0.0.0		RNA binding DNA binding nucleic acid binding double-stranded DNA binding	cytoplasm
2ho1B	[pdb]	1.90265 0.00197142	1208^ASN 1210^ARG 1215^GLY 1232^GLY 1236^LYS 1240^PRO	0.0.0.0			binding
2j9pA	[pdb]	1.91668 0.00205732	294^PRO 297^LYS 379^ASN 392^GLY 406^GLY 409^ARG	3.4.16.4	cell division peptidoglycan biosynthetic process regulation of cell shape cell cycle cell wall organization proteolysis	extracellular region	hydrolase activity serine-type D-Ala-D-Ala carboxypeptidase activity serine-type carboxypeptidase activity
2hs6B	[pdb]	1.92611 0.00210363	131^LYS 132^PRO 199^GLY 201^ASN 203^ARG 209^GLY	1.3.1.42	12-oxophytodienoate reductase activity oxidoreductase activity FMN binding catalytic activity	oxidation reduction oxylipin biosynthetic process lipid biosynthetic process fatty acid biosynthetic process metabolic process	peroxisome
2uxyA	[pdb]	1.93232 0.00215205	46^LYS 50^PRO 92^ARG 95^ASN 98^GLY 126^GLY	3.5.1.4		hydrolase activity amidase activity hydrolase activity acting on carbon-nitrogen (but not peptide) bonds	nitrogen compound metabolic process
1ehaA	[pdb]	1.93493 0.00220262	381^ASN 384^LYS 424^PRO 443^GLY 444^ARG 449^GLY	0.0.0.0		cation binding hydrolase activity hydrolyzing O-glycosyl compounds catalytic activity	trehalose biosynthetic process carbohydrate metabolic process
2qmrA	[pdb]	1.93854 0.00220281	107^ARG 111^GLY 143^ASN 150^GLY 188^PRO 189^LYS	0.0.0.0	cytoplasm nucleus nuclear pore	interspecies interaction between organisms protein transport transport protein import into nucleus translocation intracellular protein transport protein import into nucleus docking	nuclear localization sequence binding protein transporter activity binding protein binding
2z83A	[pdb]	1.93952 0.00220287	396^PRO 399^LYS 417^ASN 419^GLY 461^ARG 463^GLY	0.0.0.0	hydrolase activity ATP binding helicase activity nucleotide binding ATP-dependent helicase activity structural molecule activity serine-type endopeptidase activity RNA-directed RNA polymerase activity catalytic activity double-stranded RNA binding RNA helicase activity RNA binding nucleic acid binding methyltransferase activity methyltransferase activity hydrolase activity nucleotidyltransferase activity transferase activity ATP binding structural molecule activity helicase activity RNA-directed RNA polymerase activity nucleotide binding ATP-dependent helicase activity serine-type endopeptidase activity catalytic activity double-stranded RNA binding RNA helicase activity RNA binding nucleic acid binding	transcription RNA-dependent viral genome replication viral infectious cycle RNA metabolic process viral reproduction methylation methylation transcription RNA-dependent viral genome replication viral infectious cycle RNA metabolic process viral reproduction	viral envelope virion integral to membrane membrane virion part viral capsid membrane viral envelope viral capsid viral nucleocapsid virion integral to membrane virion part
2czgA	[pdb]	1.95534 0.00236982	26^GLY 28^GLY 50^ARG 53^ASN 378^LYS 379^PRO			metal ion binding transferase activity ATP binding magnesium ion binding nucleotide binding hydroxymethyl- formyl- and related transferase activity catalytic activity phosphoribosylglycinamide formyltransferase 2 activity	purine nucleotide biosynthetic process purine base biosynthetic process
1wflA	[pdb]	1.9555 0.00236983	23^PRO 24^LYS 39^GLY 46^ASN 50^GLY 53^ARG			in utero embryonic development vasculature development respiratory system process fibroblast migration platelet-derived growth factor receptor signaling pathway skeletal system morphogenesis smooth muscle tissue development face development	metal ion binding zinc ion binding DNA binding
2h4mA	[pdb]	1.9652 0.00249013	107^ARG 111^GLY 143^ASN 150^GLY 188^PRO 189^LYS		RNA binding nucleic acid binding nucleotide binding protein binding single-stranded DNA binding single-stranded RNA binding nuclear localization sequence binding protein transporter activity binding protein binding	cytoplasm nucleus ribonucleoprotein complex spliceosomal complex heterogeneous nuclear ribonucleoprotein complex nucleoplasm cytoplasm nucleus nuclear pore nucleolus	mRNA transport RNA splicing transport mRNA processing nuclear mRNA splicing via spliceosome RNA export from nucleus nuclear export nuclear import interspecies interaction between organisms protein transport transport protein import into nucleus translocation intracellular protein transport protein import into nucleus docking
1bpwB	[pdb]	1.97028 0.00249046	13^GLY 47^ARG 338^GLY 342^LYS 343^PRO 378^ASN	1.2.1.3, 1.2.1.8	cytoplasm	oxidation reduction metabolic process	oxidoreductase activity betaine-aldehyde dehydrogenase activity aldehyde dehydrogenase (NAD) activity
1zpdE	[pdb]	1.97446 0.00255396	62^ARG 65^GLY 91^ASN 219^LYS 224^GLY 285^PRO	4.1.1.1			metal ion binding carboxy-lyase activity lyase activity magnesium ion binding pyruvate decarboxylase activity thiamin pyrophosphate binding transferase activity catalytic activity
1t3qE	[pdb]	1.97779 0.00262017	146^VAL 153^LYS 156^TYR 164^GLU 364^LYS 366^PRO	0.0.0.0			oxidoreductase activity electron carrier activity FAD binding oxidoreductase activity electron carrier activity catalytic activity iron-sulfur cluster binding metal ion binding oxidoreductase activity electron carrier activity iron ion binding 2 iron 2 sulfur cluster binding
1xa0B	[pdb]	1.98288 0.00262053	43^ASN 160^GLY 308^PRO 312^LYS 317^GLY 322^ARG	0.0.0.0
1qkiD	[pdb]	1.98331 0.00268938	359^GLY 363^ASN 366^LYS 396^PRO 487^ARG 488^GLY	1.1.1.49	intracellular membrane-bounded organelle centrosome cytoplasm cytosol internal side of plasma membrane	oxidation reduction glucose metabolic process carbohydrate metabolic process metabolic process erythrocyte development regulation of multicellular organism growth interleukin-12 production interleukin-10 production pentose biosynthetic process response to oxidative stress glutathione metabolic process NADP biosynthetic process vasodilation by angiotensin involved in regulation of systemic arterial blood pressure angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure cytokine production erythrocyte maturation cellular response to oxidative stress negative regulation of protein amino acid glutathionylation NADPH regeneration pentose-phosphate shunt glucose 6-phosphate utilization ribose phosphate biosynthetic process lipid metabolic process cholesterol biosynthetic process pentose-phosphate shunt oxidative branch	oxidoreductase activity glucose-6-phosphate dehydrogenase activity binding catalytic activity protein homodimerization activity glucose binding NADP or NADPH binding
1jqvA	[pdb]	1.98368 0.0026894	225^LYS 226^PRO 231^ASN 233^ARG 247^GLY 264^GLY	1.3.3.1	cytoplasm cytoplasm	oxidation reduction pyrimidine nucleotide biosynthetic process metabolic process UMP biosynthetic process 'de novo' pyrimidine base biosynthetic process pyrimidine nucleotide biosynthetic process metabolic process UMP biosynthetic process 'de novo' pyrimidine base biosynthetic process oxidation reduction	oxidoreductase activity dihydroorotate oxidase activity dihydroorotate dehydrogenase activity catalytic activity oxidoreductase activity dihydroorotate oxidase activity dihydroorotate dehydrogenase activity catalytic activity
1yb5A	[pdb]	1.98555 0.00268954	170^ARG 173^GLY 192^ASN 293^GLY 296^LYS 297^PRO	1.6.5.5	cytoplasm	oxidation reduction visual perception metabolic process	oxidoreductase activity NADPH:quinone reductase activity zinc ion binding binding catalytic activity
3bohB	[pdb]	1.98625 0.00268959	79^ASN 80^ARG 81^GLY 130^GLY 198^PRO 199^LYS	0.0.0.0
2gw2A	[pdb]	1.99848 0.00283689	76^GLY 83^ASN 85^ARG 87^GLY 164^LYS 165^PRO	5.2.1.8	nuclear speck nuclear matrix nucleus nucleoplasm	peptide binding isomerase activity peptidyl-prolyl cis-trans isomerase activity cyclosporin A binding	protein folding RNA splicing
1ul1Z	[pdb]	2.00141 0.00283712	28^TRP 77^LYS 80^LYS 81^CYS 332^ARG 334^GLY		DNA repair DNA replication phosphoinositide-mediated signaling UV protection double-strand break repair base-excision repair gap-filling DNA replication DNA repair phosphoinositide-mediated signaling nucleotide-excision repair DNA gap filling cell proliferation regulation of DNA replication intracellular protein transport mismatch repair DNA replication removal of RNA primer	nucleus DNA replication factor C complex nucleus nucleoplasm PCNA complex replication fork nuclear lamina cyclin-dependent protein kinase holoenzyme complex mitochondrion	protein binding ribonuclease H activity 5'-3' exonuclease activity 5'-flap endonuclease activity DNA binding hydrolase activity exonuclease activity endonuclease activity nuclease activity double-stranded DNA specific exodeoxyribonuclease activity double-stranded DNA binding damaged DNA binding catalytic activity flap endonuclease activity manganese ion binding magnesium ion binding MutLalpha complex binding protein binding DNA binding DNA polymerase processivity factor activity purine-specific mismatch base pair DNA N-glycosylase activity dinucleotide insertion or deletion binding metal ion binding
1iokD	[pdb]	2.01498 0.00307901	33^PRO 34^LYS 452^ARG 457^ASN 459^GLY 462^GLY	0.0.0.0	ATP binding nucleotide binding protein binding unfolded protein binding	cytoplasm	protein folding cellular protein metabolic process protein refolding
1tdhA	[pdb]	2.02168 0.00316348	2^PRO 53^GLY 54^LYS 134^GLY 169^ARG 172^ASN	4.2.99.18	cytoplasm nucleus	hydrolase activity acting on glycosyl bonds protein C-terminus binding lyase activity hydrolase activity catalytic activity DNA binding DNA-(apurinic or apyrimidinic site) lyase activity hydrolase activity hydrolyzing N-glycosyl compounds zinc ion binding damaged DNA binding nucleic acid binding DNA N-glycosylase activity	response to oxidative stress negative regulation of nuclease activity base-excision repair metabolic process response to DNA damage stimulus DNA repair nucleotide-excision repair
2r6iA	[pdb]	2.02246 0.00316355	0^GLY 62^LYS 63^PRO 95^ARG 98^ASN 103^GLY	0.0.0.0
1mroC	[pdb]	2.02739 0.00325104	151^ARG 152^GLY 188^LYS 189^ASN 192^GLY 198^PRO	2.8.4.1		methanogenesis methanogenesis methanogenesis	transferase activity coenzyme-B sulfoethylthiotransferase activity transferase activity coenzyme-B sulfoethylthiotransferase activity metal ion binding transferase activity nickel ion binding coenzyme-B sulfoethylthiotransferase activity
1y7eA	[pdb]	2.02782 0.00325108	88^GLY 90^ASN 274^PRO 276^LYS 420^GLY 422^ARG	0.0.0.0	metal ion binding hydrolase activity zinc ion binding metallopeptidase activity peptidase activity aminopeptidase activity aminopeptidase activity peptidase activity metallopeptidase activity zinc ion binding hydrolase activity metal ion binding aminopeptidase activity peptidase activity metallopeptidase activity zinc ion binding hydrolase activity metal ion binding	proteolysis proteolysis proteolysis	vacuole vacuole vacuole
1f76E	[pdb]	2.02851 0.00325114	90^ARG 119^GLY 141^GLY 142^LYS 143^ASN 147^PRO	1.3.3.1	oxidation reduction pyrimidine nucleotide biosynthetic process metabolic process UMP biosynthetic process 'de novo' pyrimidine base biosynthetic process	oxidoreductase activity dihydroorotate oxidase activity dihydroorotate dehydrogenase activity catalytic activity	plasma membrane membrane
2ct6A	[pdb]	2.03263 0.00325152	59^ASN 62^PRO 64^LYS 79^GLY 81^ARG 84^GLY			SH3 domain binding	nucleus
2simA	[pdb]	2.03829 0.00334231	276^ARG 279^GLY 302^ASN 332^PRO 333^LYS 341^GLY	3.2.1.18		hydrolase activity acting on glycosyl bonds hydrolase activity exo-alpha-sialidase activity	metabolic process pathogenesis
2ccdB	[pdb]	2.03901 0.00334238	589^PRO 590^LYS 596^ASN 599^GLY 676^GLY 693^ARG	1.11.1.7, 1.11.1.6		heme binding peroxidase activity catalase activity metal ion binding oxidoreductase activity iron ion binding	response to oxidative stress oxidation reduction hydrogen peroxide catabolic process
2g5wA	[pdb]	2.03903 0.00334238	131^LYS 132^PRO 200^GLY 202^ASN 204^ARG 210^GLY	1.3.1.42	12-oxophytodienoate reductase activity oxidoreductase activity FMN binding catalytic activity	peroxisome	response to fungus response to ozone jasmonic acid biosynthetic process oxidation reduction oxylipin biosynthetic process lipid biosynthetic process fatty acid biosynthetic process metabolic process
2qbwA	[pdb]	2.04658 0.00353341	13^VAL 15^HOH 17^HOH 25^HOH 43^PRO 46^LYS	0.0.0.0	cytoplasm hemidesmosome nucleus basal plasma membrane cell junction basement membrane	integrin-mediated signaling pathway intermediate filament cytoskeleton organization establishment or maintenance of epithelial cell apical/basal polarity basal protein localization epidermal growth factor receptor signaling pathway cell cycle cell growth cell adhesion signal transduction	protein binding ErbB-2 class receptor binding integrin binding structural constituent of cytoskeleton
2nteB	[pdb]	2.05798 0.00373819	627^GLY 656^GLY 659^ARG 663^ASN 669^PRO 670^LYS	0.0.0.0	BRCA1-A complex BRCA1-BARD1 complex ubiquitin ligase complex nucleus cytoplasm intracellular	DNA repair modification-dependent protein catabolic process cell cycle arrest positive regulation of apoptosis regulation of phosphorylation tissue homeostasis protein ubiquitination positive regulation of protein catabolic process negative regulation of protein export from nucleus negative regulation of mRNA 3'-end processing response to DNA damage stimulus negative regulation of apoptosis	ligase activity RNA binding protein binding kinase binding ubiquitin-protein ligase activity protein heterodimerization activity protein homodimerization activity metal ion binding zinc ion binding
2f2lA	[pdb]	2.06004 0.00373841	376^VAL 431^GLY 432^ILE 435^ILE 479^THR 484^GLU		integral to plasma membrane membrane integral to membrane integral to membrane membrane	peptidoglycan binding N-acetylmuramoyl-L-alanine amidase activity protein binding Gram-negative bacterial binding peptidoglycan receptor activity N-acetylmuramoyl-L-alanine amidase activity protein binding protein dimerization activity peptidoglycan binding pattern recognition receptor activity	peptidoglycan catabolic process innate immune response immune response antibacterial humoral response innate immune response immune response peptidoglycan catabolic process defense response to Gram-negative bacterium antimicrobial humoral response response to bacterium positive regulation of antibacterial peptide biosynthetic process phagocytosis
3dmcB	[pdb]	2.0603 0.00373844	103^PRO 105^LYS 107^ARG 127^GLY 130^GLY 133^ASN	0.0.0.0
2vy0A	[pdb]	2.06305 0.00373874	159^ASN 161^ARG 164^GLY 169^GLY 256^LYS 257^PRO	0.0.0.0		carbohydrate metabolic process	hydrolase activity hydrolyzing O-glycosyl compounds
2dreB	[pdb]	2.06501 0.00384582	80^ASN 115^PRO 116^LYS 118^GLY 123^ARG 142^GLY	0.0.0.0			endopeptidase inhibitor activity
2yybB	[pdb]	2.06898 0.00384626	109^ASN 114^ARG 117^GLY 123^PRO 129^LYS 130^GLY	0.0.0.0
2v6oA	[pdb]	2.07126 0.00395509	413^GLY 414^ARG 435^ASN 437^GLY 438^LYS 439^PRO	0.0.0.0	cell redox homeostasis oxidation reduction	cytoplasm	thioredoxin-disulfide reductase activity FAD binding oxidoreductase activity protein disulfide oxidoreductase activity electron carrier activity NADP or NADPH binding
2i3yA	[pdb]	2.07426 0.00395542	105^GLY 106^LYS 109^PRO 164^GLY 180^ARG 182^ASN	1.11.1.9	extracellular region	oxidation reduction lipid metabolic process response to oxidative stress	oxidoreductase activity peroxidase activity glutathione peroxidase activity
1yzcA	[pdb]	2.07582 0.0039556	56^PRO 59^LYS 64^GLY 98^GLY 99^ARG 102^ASN	0.0.0.0	electron transport chain transport	metal ion binding iron ion binding heme binding electron carrier activity	periplasmic space
2ywoA	[pdb]	2.07722 0.00406607	133^GLY 134^ARG 136^ASN 140^LYS 142^PRO 172^GLY	0.0.0.0		cell redox homeostasis	isomerase activity oxidoreductase activity antioxidant activity
2f3oA	[pdb]	2.07777 0.00406613	590^PRO 591^LYS 593^GLY 594^ASN 667^ARG 669^GLY	0.0.0.0	cytoplasm	lyase activity formate C-acetyltransferase activity catalytic activity	metabolic process glucose metabolic process
1n8wA	[pdb]	2.08963 0.00429853	296^LYS 375^GLY 384^PRO 387^ASN 389^ARG 391^GLY	2.3.3.9	cytoplasm	transferase activity magnesium ion binding malate synthase activity catalytic activity	tricarboxylic acid cycle glyoxylate cycle
3f7sA	[pdb]	2.09197 0.00429881	90^ASN 91^ARG 93^GLY 102^GLY 140^LYS 141^PRO	0.0.0.0
1a65A	[pdb]	2.09304 0.00429894	175^ARG 179^GLY 262^PRO 264^LYS 268^GLY 278^ASN	0.0.0.0		metal ion binding oxidoreductase activity copper ion binding laccase activity	oxidation reduction
2d3qB	[pdb]	2.09697 0.00442018	102^GLY 311^LYS 314^PRO 368^ARG 373^ASN 395^GLY	0.0.0.0
3c2uD	[pdb]	2.09764 0.00442026	419^ASN 493^PRO 496^LYS 503^ARG 506^GLY 510^GLY	0.0.0.0		carbohydrate metabolic process	hydrolase activity hydrolyzing O-glycosyl compounds
1fj2B	[pdb]	2.09932 0.00442047	150^GLY 153^GLY 157^ARG 185^LYS 189^ASN 190^PRO		cytoplasm	fatty acid metabolic process lipid metabolic process	hydrolase activity lysophospholipase activity
2o7jA	[pdb]	2.10059 0.00442063	270^ASN 273^LYS 274^PRO 419^GLY 459^GLY 463^ARG	0.0.0.0		transport	transporter activity
2e9fA	[pdb]	2.10171 0.00454505	119^ARG 124^GLY 194^ASN 220^GLY 222^LYS 224^PRO	4.3.2.1	cellular amino acid biosynthetic process arginine biosynthetic process arginine biosynthetic process via ornithine	cytoplasm	lyase activity argininosuccinate lyase activity catalytic activity
2w0jA	[pdb]	2.10336 0.00454527	342^GLY 403^GLY 405^ASN 406^ARG 471^PRO 472^LYS	2.7.11.1	DNA damage response signal transduction resulting in induction of apoptosis DNA damage checkpoint response to DNA damage stimulus cell cycle DNA damage response signal transduction protein amino acid phosphorylation	PML body nucleus	protein binding protein serine/threonine kinase activity metal ion binding transferase activity kinase activity ATP binding magnesium ion binding nucleotide binding protein kinase activity
3eynA	[pdb]	2.10414 0.00454537	41^PRO 43^LYS 45^ASN 128^ARG 130^GLY 211^GLY		fatty acid metabolic process lipid metabolic process metabolic process	metal ion binding ligase activity ATP binding magnesium ion binding nucleotide binding butyrate-CoA ligase activity catalytic activity	mitochondrial matrix mitochondrion
1kkoA	[pdb]	2.10492 0.00454547	76^GLY 78^GLY 80^ARG 281^LYS 282^PRO 311^ASN	0.0.0.0			lyase activity
2cdcA	[pdb]	2.10872 0.00467379	90^ARG 102^GLY 113^GLY 307^ASN 310^LYS 311^PRO	0.0.0.0		oxidation reduction metabolic process	oxidoreductase activity glucose 1-dehydrogenase activity zinc ion binding binding catalytic activity
2jwnA	[pdb]	2.11126 0.00467413	43^ASN 47^GLY 77^PRO 78^LYS 104^GLY 105^ARG		biological_process	cytoplasm	nucleic acid binding nucleotide binding poly(A) RNA binding RNA binding
3bs0A	[pdb]	2.11127 0.00467413	140^GLY 220^GLY 222^ARG 240^ASN 242^LYS 278^PRO	0.0.0.0
2avwB	[pdb]	2.1136 0.00467444	182^ASN 199^GLY 201^LYS 203^PRO 214^ARG 215^GLY	0.0.0.0			peptidase activity
2h3lB	[pdb]	2.1155 0.00480611	1342^GLY 1343^ARG 1345^ASN 1353^GLY 1371^PRO 1374^LYS		cytoplasm hemidesmosome nucleus basal plasma membrane cell junction basement membrane	integrin-mediated signaling pathway intermediate filament cytoskeleton organization establishment or maintenance of epithelial cell apical/basal polarity basal protein localization epidermal growth factor receptor signaling pathway cell cycle cell growth cell adhesion signal transduction	protein binding ErbB-2 class receptor binding integrin binding structural constituent of cytoskeleton
2gya2	[pdb]	2.11784 0.00480643	57^GLU 60^LYS 134^ALA 163^TYR 199^SER 200^ASP		rRNA binding RNA binding structural constituent of ribosome protein binding structural constituent of ribosome protein binding structural constituent of ribosome protein binding rRNA binding RNA binding structural constituent of ribosome protein binding rRNA binding RNA binding structural constituent of ribosome protein binding rRNA binding RNA binding structural constituent of ribosome rRNA binding RNA binding structural constituent of ribosome protein binding structural constituent of ribosome rRNA binding RNA binding structural constituent of ribosome protein binding rRNA binding RNA binding structural constituent of ribosome protein binding rRNA binding RNA binding transferase activity structural constituent of ribosome protein binding structural constituent of ribosome structural constituent of ribosome rRNA binding RNA binding structural constituent of ribosome rRNA binding RNA binding 5S rRNA binding structural constituent of ribosome protein binding RNA binding tRNA binding structural constituent of ribosome rRNA binding RNA binding tRNA binding structural constituent of ribosome structural constituent of ribosome rRNA binding RNA binding tRNA binding structural constituent of ribosome rRNA binding RNA binding nucleotide binding protein binding rRNA binding RNA binding tRNA binding structural constituent of ribosome rRNA binding RNA binding structural constituent of ribosome rRNA binding RNA binding structural constituent of ribosome protein binding rRNA binding RNA binding structural constituent of ribosome rRNA binding RNA binding structural constituent of ribosome rRNA binding RNA binding tRNA binding structural constituent of ribosome protein binding rRNA binding RNA binding structural constituent of ribosome protein binding	ribonucleoprotein complex ribosome intracellular ribonucleoprotein complex ribosome intracellular ribonucleoprotein complex ribosome large ribosomal subunit ribonucleoprotein complex ribosome intracellular ribonucleoprotein complex ribosome large ribosomal subunit intracellular ribonucleoprotein complex ribosome intracellular ribonucleoprotein complex ribosome intracellular intracellular ribonucleoprotein complex ribosome intracellular ribonucleoprotein complex ribosome large ribosomal subunit intracellular ribonucleoprotein complex ribosome large ribosomal subunit intracellular ribonucleoprotein complex ribosome intracellular ribonucleoprotein complex ribosome large ribosomal subunit intracellular ribonucleoprotein complex ribosome intracellular ribonucleoprotein complex ribosome intracellular ribonucleoprotein complex ribosome intracellular ribonucleoprotein complex ribosome intracellular ribonucleoprotein complex ribosome intracellular ribonucleoprotein complex ribosome intracellular ribonucleoprotein complex ribosome ribonucleoprotein complex ribosome intracellular ribonucleoprotein complex ribosome intracellular ribonucleoprotein complex ribosome intracellular ribonucleoprotein complex ribosome intracellular ribonucleoprotein complex ribosome large ribosomal subunit intracellular ribonucleoprotein complex ribosome large ribosomal subunit intracellular ribonucleoprotein complex ribosome intracellular	translation translation translation translation translation translation response to antibiotic translation regulation of transcription translation response to antibiotic translation translation translation translation translation translation translation translation translation translation translation translation translation translation translation ribosomal large subunit assembly translation regulation of translation translation RNA processing response to antibiotic regulation of translation regulation of transcription DNA-dependent transcription termination transcription translation
3bocA	[pdb]	2.12041 0.00494181	289^ASN 290^ARG 291^GLY 340^GLY 408^PRO 409^LYS	0.0.0.0
1iaxB	[pdb]	2.12576 0.00494255	56^ASN 278^LYS 283^PRO 338^ARG 340^GLY 363^GLY	4.4.1.14		lyase activity 1-aminocyclopropane-1-carboxylate synthase activity pyridoxal phosphate binding transferase activity transferring nitrogenous groups catalytic activity	ripening ethylene biosynthetic process biosynthetic process
1ua4A	[pdb]	2.13873 0.00536228	109^ARG 111^GLY 377^ASN 432^PRO 433^LYS 437^GLY	2.7.1.147	cytoplasm	glycolysis glucose metabolic process carbohydrate metabolic process	metal ion binding transferase activity kinase activity magnesium ion binding ADP-specific glucokinase activity phosphotransferase activity alcohol group as acceptor glucokinase activity
2gn2A	[pdb]	2.13976 0.00536243	20^ARG 23^GLY 64^ASN 156^PRO 157^LYS 161^GLY	4.3.1.19		lyase activity catalytic activity L-threonine ammonia-lyase activity pyridoxal phosphate binding	metabolic process cellular amino acid metabolic process
1pe4A	[pdb]	2.14311 0.00536292	5^PRO 9^ASN 12^LYS 58^GLY 63^GLY 66^ARG		extracellular region	ion channel inhibitor activity sodium channel inhibitor activity	pathogenesis defense response
2k46A	[pdb]	2.14334 0.00536296	15^ASN 18^GLY 31^LYS 33^PRO 45^GLY 65^ARG		carbohydrate binding	membrane endoplasmic reticulum endoplasmic reticulum membrane integral to membrane	protein amino acid terminal N-glycosylation carbohydrate metabolic process
1q1zA	[pdb]	2.14417 0.00536308	69^PRO 70^LYS 148^ASN 150^ARG 276^GLY 279^GLY	2.8.2.2	cytosol cytoplasm	steroid metabolic process lipid metabolic process	steroid sulfotransferase activity transferase activity alcohol sulfotransferase activity sulfotransferase activity protein binding
2v4jD	[pdb]	2.14457 0.00536314	165^ILE 168^GLU 170^PHE 172^ASP 211^PRO 213^ILE	1.8.99.3	4 iron 4 sulfur cluster binding iron-sulfur cluster binding metal ion binding oxidoreductase activity iron ion binding heme binding hydrogensulfite reductase activity electron carrier activity 4 iron 4 sulfur cluster binding iron-sulfur cluster binding metal ion binding oxidoreductase activity iron ion binding hydrogensulfite reductase activity heme binding electron carrier activity oxidoreductase activity hydrogensulfite reductase activity	cytoplasm	oxidation reduction oxidation reduction oxidation reduction
1rfeA	[pdb]	2.14744 0.00550958	106^GLY 122^LYS 123^PRO 130^ASN 132^ARG 134^GLY	0.0.0.0			FMN binding

PDB ID

LRMSD /
p-value

Matching Residues

Gene Ontology annotations

Biological Process

Cellular Component

Molecular Function

3b54B

[pdb]

1.22993
9.26107e-05

13^LYS 14^PRO 93^GLY 106^ARG 116^ASN 120^GLY

2.7.4.6

metal ion binding
transferase activity
kinase activity
ATP binding
magnesium ion binding
nucleotide binding
nucleoside diphosphate kinase activity
protein binding
identical protein binding

mitochondrial intermembrane space
cytoplasm
mitochondrion
cytosol

nucleotide metabolic process
nucleoside triphosphate biosynthetic process
response to DNA damage stimulus
nucleoside diphosphate phosphorylation
CTP biosynthetic process
UTP biosynthetic process
GTP biosynthetic process
DNA repair

1ndlC

[pdb]

1.32392
0.000297675

13^LYS 14^PRO 93^GLY 106^ARG 116^ASN 120^GLY

2.7.4.6

CTP biosynthetic process
UTP biosynthetic process
GTP biosynthetic process
nucleotide metabolic process
protein amino acid autophosphorylation
peptidyl-serine phosphorylation
epithelial cell migration
open tracheal system
open tracheal system development
mitosis
microtubule-based process
protein amino acid phosphorylation
nucleoside diphosphate phosphorylation

kinase activity
magnesium ion binding
ATP binding
nucleoside diphosphate kinase activity
metal ion binding
transferase activity
nucleotide binding
microtubule binding
GTP binding

nuclear microtubule
cytoplasm
microtubule
cytoskeleton

1zs6D

[pdb]

1.3331
0.000335478

29^LYS 30^PRO 109^GLY 122^ARG 132^ASN 136^GLY

2.7.4.6

cytosol

metal ion binding
transferase activity
kinase activity
ATP binding
magnesium ion binding
nucleotide binding
nucleoside diphosphate kinase activity

nucleotide metabolic process
apoptosis
induction of apoptosis
CTP biosynthetic process
UTP biosynthetic process
GTP biosynthetic process

3bbcF

[pdb]

1.33765
0.000355157

12^LYS 13^PRO 92^GLY 105^ARG 115^ASN 119^GLY

2.7.4.6

nucleus
cytoplasm
lamellipodium
ruffle

regulation of transcription
regulation of transcription
DNA-dependent
nucleoside triphosphate biosynthetic process
negative regulation of cell proliferation
negative regulation of cell cycle
nucleotide metabolic process
cell cycle
transcription
CTP biosynthetic process
UTP biosynthetic process
GTP biosynthetic process
positive regulation of epithelial cell proliferation
regulation of epidermis development
positive regulation of keratinocyte differentiation
negative regulation of apoptosis
cell adhesion

transcription factor activity
ATP binding
nucleoside diphosphate kinase activity
metal ion binding
transferase activity
kinase activity
DNA binding
magnesium ion binding
nucleotide binding
protein binding

1w7wF

[pdb]

1.33818
0.000355168

11^LYS 12^PRO 91^GLY 104^ARG 114^ASN 118^GLY

0.0.0.0

CTP biosynthetic process
UTP biosynthetic process
GTP biosynthetic process

transferase activity
kinase activity
nucleoside diphosphate kinase activity
ATP binding
nucleotide binding

1sp3A

[pdb]

1.34761
0.000375401

70^ASN 73^ARG 114^GLY 348^PRO 349^LYS 352^GLY

0.0.0.0

1xiqB

[pdb]

1.34884
0.000375426

9^LYS 10^PRO 89^GLY 102^ARG 112^ASN 116^GLY

0.0.0.0

CTP biosynthetic process
UTP biosynthetic process
GTP biosynthetic process

transferase activity
kinase activity
ATP binding
nucleoside diphosphate kinase activity
nucleotide binding

1nclA

[pdb]

1.35734
0.000416674

16^LYS 17^PRO 96^GLY 109^ARG 119^ASN 123^GLY

2.7.4.6

cytoplasm

metal ion binding
transferase activity
kinase activity
ATP binding
magnesium ion binding
nucleotide binding
nucleoside diphosphate kinase activity

nucleotide metabolic process
CTP biosynthetic process
UTP biosynthetic process
GTP biosynthetic process

1u8wB

[pdb]

1.36178
0.000416767

9^LYS 10^PRO 89^GLY 102^ARG 112^ASN 116^GLY

2.7.4.6

apoplast
chloroplast
plasma membrane
vacuole

metal ion binding
transferase activity
kinase activity
ATP binding
magnesium ion binding
nucleotide binding
nucleoside diphosphate kinase activity

response to cadmium ion
response to salt stress
nucleotide metabolic process
CTP biosynthetic process
UTP biosynthetic process
GTP biosynthetic process

1nb2A

[pdb]

1.36494
0.000437622

10^LYS 11^PRO 90^GLY 103^ARG 113^ASN 117^GLY

0.0.0.0

ATP binding
nucleoside diphosphate kinase activity

CTP biosynthetic process
UTP biosynthetic process
GTP biosynthetic process

2vu5A

[pdb]

1.36918
0.000458789

9^LYS 10^PRO 89^GLY 102^ARG 112^ASN 116^GLY

0.0.0.0

cytoplasm

metal ion binding
transferase activity
kinase activity
ATP binding
magnesium ion binding
nucleotide binding
nucleoside diphosphate kinase activity

nucleotide metabolic process
CTP biosynthetic process
UTP biosynthetic process
GTP biosynthetic process

1bhnE

[pdb]

1.37092
0.000458827

12^LYS 13^PRO 92^GLY 105^ARG 115^ASN 119^GLY

2.7.4.6

metal ion binding
transferase activity
kinase activity
ATP binding
magnesium ion binding
nucleotide binding
nucleoside diphosphate kinase activity
protein binding

nucleotide metabolic process
CTP biosynthetic process
UTP biosynthetic process
GTP biosynthetic process
endocytosis
nervous system development
cell differentiation

plasma membrane
cytoplasm
membrane
nucleus
mitochondrion

1wklB

[pdb]

1.37675
0.000480258

9^LYS 10^PRO 89^GLY 102^ARG 112^ASN 116^GLY

2.7.4.6

cytoplasm

metal ion binding
transferase activity
kinase activity
ATP binding
magnesium ion binding
nucleotide binding
nucleoside diphosphate kinase activity

nucleotide metabolic process
CTP biosynthetic process
UTP biosynthetic process
GTP biosynthetic process

2hveB

[pdb]

1.39206
0.000523656

12^LYS 13^PRO 92^GLY 105^ARG 115^ASN 119^GLY

2.7.4.6

cytoplasm
nucleus

positive regulation of DNA binding
regulation of apoptosis
negative regulation of cell proliferation
negative regulation of cell cycle
nucleotide metabolic process
cell cycle
CTP biosynthetic process
UTP biosynthetic process
positive regulation of epithelial cell proliferation
endocytosis
nervous system development
cell differentiation
GTP biosynthetic process

protein binding
GTP binding
magnesium ion binding
DNA binding
deoxyribonuclease activity
ATP binding
nucleoside diphosphate kinase activity
metal ion binding
transferase activity
kinase activity
nucleotide binding
identical protein binding

2az3E

[pdb]

1.41167
0.000610362

13^LYS 14^PRO 93^GLY 106^ARG 116^ASN 120^GLY

2.7.4.6

cytoplasm

metal ion binding
transferase activity
kinase activity
ATP binding
magnesium ion binding
nucleotide binding
nucleoside diphosphate kinase activity

nucleotide metabolic process
CTP biosynthetic process
UTP biosynthetic process
GTP biosynthetic process

1pkuD

[pdb]

1.45039
0.000735482

12^LYS 13^PRO 92^GLY 105^ARG 115^ASN 119^GLY

2.7.4.6

metal ion binding
transferase activity
kinase activity
ATP binding
magnesium ion binding
nucleotide binding
nucleoside diphosphate kinase activity

nucleotide metabolic process
CTP biosynthetic process
UTP biosynthetic process
GTP biosynthetic process

1s57A

[pdb]

1.464
0.000774397

91^LYS 92^PRO 171^GLY 184^ARG 194^ASN 198^GLY

2.7.4.6

chloroplast envelope
thylakoid
chloroplast stroma
chloroplast
cytoplasm
nucleus
plastid

protein binding
nucleoside diphosphate kinase activity
metal ion binding
transferase activity
kinase activity
ATP binding
magnesium ion binding
identical protein binding
nucleotide binding

response to hydrogen peroxide
auxin mediated signaling pathway
red
far-red light phototransduction
response to UV
nucleotide metabolic process
CTP biosynthetic process
UTP biosynthetic process
GTP biosynthetic process

2nckL

[pdb]

1.46738
0.000774461

11^LYS 12^PRO 91^GLY 104^ARG 114^ASN 118^GLY

2.7.4.6

cytoplasm

metal ion binding
transferase activity
kinase activity
ATP binding
magnesium ion binding
nucleotide binding
nucleoside diphosphate kinase activity

nucleotide metabolic process
CTP biosynthetic process
UTP biosynthetic process
GTP biosynthetic process

2hurC

[pdb]

1.50378
0.000881242

11^LYS 12^PRO 91^GLY 104^ARG 114^ASN 118^GLY

2.7.4.6

cytoplasm

metal ion binding
transferase activity
kinase activity
ATP binding
magnesium ion binding
nucleotide binding
nucleoside diphosphate kinase activity
protein binding

nucleotide metabolic process
CTP biosynthetic process
UTP biosynthetic process
GTP biosynthetic process

2ha1A

[pdb]

1.50688
0.000897123

16^ASN 62^GLY 64^LYS 65^PRO 141^GLY 143^ARG

ER-Golgi intermediate compartment
proteinaceous extracellular matrix
extracellular region
platelet alpha granule lumen
fibrinogen complex

collagen binding
protein binding
extracellular matrix structural constituent
heparin binding

transmembrane receptor protein tyrosine kinase signaling pathway
response to wounding
cell migration
cell adhesion
regulation of cell shape
acute-phase response
peptide cross-linking
substrate adhesion-dependent cell spreading

1k44B

[pdb]

1.52194
0.000927676

10^LYS 11^PRO 90^GLY 104^ARG 114^ASN 118^GLY

2.7.4.6

cytoplasm

metal ion binding
transferase activity
kinase activity
ATP binding
magnesium ion binding
nucleotide binding
nucleoside diphosphate kinase activity

nucleotide metabolic process
CTP biosynthetic process
UTP biosynthetic process
GTP biosynthetic process

2d3aH

[pdb]

1.62496
0.00112791

237^LYS 238^PRO 244^ASN 247^GLY 295^ARG 312^GLY

6.3.1.2

cytoplasm

nitrogen compound metabolic process
glutamine biosynthetic process

nucleotide binding
ATP binding
ligase activity
glutamate-ammonia ligase activity
catalytic activity

2vf7B

[pdb]

1.65178
0.00116635

620^PRO 623^LYS 626^GLY 628^ASN 631^ARG 638^GLY

0.0.0.0

SOS response
response to DNA damage stimulus
DNA repair
nucleotide-excision repair

cytoplasm
excinuclease repair complex

metal ion binding
zinc ion binding
ATP binding
nuclease activity
DNA binding
nucleotide binding
ATPase activity
excinuclease ABC activity

2v8oA

[pdb]

1.6617
0.00118555

396^PRO 399^LYS 417^ASN 419^GLY 461^ARG 463^GLY

2.7.7.48, 3.4.21.91

membrane
viral envelope
viral capsid
viral nucleocapsid
virion
integral to membrane
virion part

methylation
transcription
RNA-dependent
viral genome replication
viral infectious cycle
RNA metabolic process
viral reproduction

methyltransferase activity
hydrolase activity
nucleotidyltransferase activity
transferase activity
ATP binding
structural molecule activity
helicase activity
RNA-directed RNA polymerase activity
nucleotide binding
ATP-dependent helicase activity
serine-type endopeptidase activity
catalytic activity
double-stranded RNA binding
RNA helicase activity
RNA binding
nucleic acid binding

1ud1C

[pdb]

1.77859
0.00142068

77^GLY 79^GLY 116^ASN 118^ARG 247^LYS 248^PRO

nutrient reservoir activity

1llwA

[pdb]

1.79025
0.0014384

1376^ASN 1378^ARG 1398^GLY 1414^GLY 1475^PRO 1476^LYS

1.4.7.1

metabolic process
nitrogen compound metabolic process
glutamate biosynthetic process
cellular amino acid biosynthetic process
glutamine metabolic process
oxidation reduction

oxidoreductase activity
glutamate synthase activity
catalytic activity
protein binding
3 iron
4 sulfur cluster binding
iron-sulfur cluster binding
metal ion binding
iron ion binding
glutamate synthase (ferredoxin) activity

3blvG

[pdb]

1.79274
0.00145683

129^VAL 131^LEU 134^ILE 157^ILE 158^LYS 240^SER

0.0.0.0

metal ion binding
manganese ion binding
oxidoreductase activity
catalytic activity
RNA binding
magnesium ion binding
isocitrate dehydrogenase (NAD+) activity
oxidoreductase activity
acting on the CH-OH group of donors
NAD or NADP as acceptor
protein binding
metal ion binding
manganese ion binding
oxidoreductase activity
catalytic activity
RNA binding
magnesium ion binding
isocitrate dehydrogenase (NAD+) activity
protein binding
oxidoreductase activity
acting on the CH-OH group of donors
NAD or NADP as acceptor
NAD or NADH binding
NAD or NADH binding

mitochondrion
mitochondrial isocitrate dehydrogenase complex (NAD+)
mitochondrial matrix
mitochondrion
mitochondrial nucleoid
mitochondrial isocitrate dehydrogenase complex (NAD+)
mitochondrial matrix

oxidation reduction
tricarboxylic acid cycle
glutamate biosynthetic process
isocitrate metabolic process
metabolic process
oxidation reduction
tricarboxylic acid cycle
glutamate biosynthetic process
isocitrate metabolic process
metabolic process

1wfiA

[pdb]

1.80341
0.00149517

1^GLY 7^GLY 9^ASN 11^ARG 106^LYS 109^PRO

cell division
mitosis
cell cycle

nucleus
microtubule
cytoskeleton
cytoplasm

protein binding

1po0A

[pdb]

1.81028
0.0015156

86^GLY 348^PRO 353^LYS 355^ASN 390^ARG 407^GLY

cell outer membrane
membrane
plasma membrane
outer membrane

iron ion binding
receptor activity
siderophore-iron transmembrane transporter activity
transporter activity

iron ion transport
ion transport
transport
siderophore transport

1zkmC

[pdb]

1.81688
0.0015371

37^GLY 67^ASN 70^ARG 82^PRO 83^LYS 191^GLY

nucleotidyltransferase activity
transferase activity
binding
catalytic activity

thiamin biosynthetic process
metabolic process

3ffjB

[pdb]

1.83891
0.0016087

59^GLY 61^ASN 63^ARG 64^GLY 433^LYS 436^PRO

0.0.0.0

carbohydrate metabolic process

hydrolase activity
hydrolyzing O-glycosyl compounds

2h9uA

[pdb]

1.88292
0.00181707

12^GLY 14^LYS 15^PRO 41^GLY 42^ARG 43^ASN

0.0.0.0

RNA binding
DNA binding
nucleic acid binding
double-stranded DNA binding

cytoplasm

2ho1B

[pdb]

1.90265
0.00197142

1208^ASN 1210^ARG 1215^GLY 1232^GLY 1236^LYS 1240^PRO

0.0.0.0

binding

2j9pA

[pdb]

1.91668
0.00205732

294^PRO 297^LYS 379^ASN 392^GLY 406^GLY 409^ARG

3.4.16.4

cell division
peptidoglycan biosynthetic process
regulation of cell shape
cell cycle
cell wall organization
proteolysis

extracellular region

hydrolase activity
serine-type D-Ala-D-Ala carboxypeptidase activity
serine-type carboxypeptidase activity

2hs6B

[pdb]

1.92611
0.00210363

131^LYS 132^PRO 199^GLY 201^ASN 203^ARG 209^GLY

1.3.1.42

12-oxophytodienoate reductase activity
oxidoreductase activity
FMN binding
catalytic activity

oxidation reduction
oxylipin biosynthetic process
lipid biosynthetic process
fatty acid biosynthetic process
metabolic process

peroxisome

2uxyA

[pdb]

1.93232
0.00215205

46^LYS 50^PRO 92^ARG 95^ASN 98^GLY 126^GLY

3.5.1.4

hydrolase activity
amidase activity
hydrolase activity
acting on carbon-nitrogen (but not peptide) bonds

nitrogen compound metabolic process

1ehaA

[pdb]

1.93493
0.00220262

381^ASN 384^LYS 424^PRO 443^GLY 444^ARG 449^GLY

0.0.0.0

cation binding
hydrolase activity
hydrolyzing O-glycosyl compounds
catalytic activity

trehalose biosynthetic process
carbohydrate metabolic process

2qmrA

[pdb]

1.93854
0.00220281

107^ARG 111^GLY 143^ASN 150^GLY 188^PRO 189^LYS

0.0.0.0

cytoplasm
nucleus
nuclear pore

interspecies interaction between organisms
protein transport
transport
protein import into nucleus
translocation
intracellular protein transport
protein import into nucleus
docking

nuclear localization sequence binding
protein transporter activity
binding
protein binding

2z83A

[pdb]

1.93952
0.00220287

396^PRO 399^LYS 417^ASN 419^GLY 461^ARG 463^GLY

0.0.0.0

hydrolase activity
ATP binding
helicase activity
nucleotide binding
ATP-dependent helicase activity
structural molecule activity
serine-type endopeptidase activity
RNA-directed RNA polymerase activity
catalytic activity
double-stranded RNA binding
RNA helicase activity
RNA binding
nucleic acid binding
methyltransferase activity
methyltransferase activity
hydrolase activity
nucleotidyltransferase activity
transferase activity
ATP binding
structural molecule activity
helicase activity
RNA-directed RNA polymerase activity
nucleotide binding
ATP-dependent helicase activity
serine-type endopeptidase activity
catalytic activity
double-stranded RNA binding
RNA helicase activity
RNA binding
nucleic acid binding

transcription
RNA-dependent
viral genome replication
viral infectious cycle
RNA metabolic process
viral reproduction
methylation
methylation
transcription
RNA-dependent
viral genome replication
viral infectious cycle
RNA metabolic process
viral reproduction

viral envelope
virion
integral to membrane
membrane
virion part
viral capsid
membrane
viral envelope
viral capsid
viral nucleocapsid
virion
integral to membrane
virion part

2czgA

[pdb]

1.95534
0.00236982

26^GLY 28^GLY 50^ARG 53^ASN 378^LYS 379^PRO

metal ion binding
transferase activity
ATP binding
magnesium ion binding
nucleotide binding
hydroxymethyl-
formyl- and related transferase activity
catalytic activity
phosphoribosylglycinamide formyltransferase 2 activity

purine nucleotide biosynthetic process
purine base biosynthetic process

1wflA

[pdb]

1.9555
0.00236983

23^PRO 24^LYS 39^GLY 46^ASN 50^GLY 53^ARG

in utero embryonic development
vasculature development
respiratory system process
fibroblast migration
platelet-derived growth factor receptor signaling pathway
skeletal system morphogenesis
smooth muscle tissue development
face development

metal ion binding
zinc ion binding
DNA binding

2h4mA

[pdb]

1.9652
0.00249013

107^ARG 111^GLY 143^ASN 150^GLY 188^PRO 189^LYS

RNA binding
nucleic acid binding
nucleotide binding
protein binding
single-stranded DNA binding
single-stranded RNA binding
nuclear localization sequence binding
protein transporter activity
binding
protein binding

cytoplasm
nucleus
ribonucleoprotein complex
spliceosomal complex
heterogeneous nuclear ribonucleoprotein complex
nucleoplasm
cytoplasm
nucleus
nuclear pore
nucleolus

mRNA transport
RNA splicing
transport
mRNA processing
nuclear mRNA splicing
via spliceosome
RNA export from nucleus
nuclear export
nuclear import
interspecies interaction between organisms
protein transport
transport
protein import into nucleus
translocation
intracellular protein transport
protein import into nucleus
docking

1bpwB

[pdb]

1.97028
0.00249046

13^GLY 47^ARG 338^GLY 342^LYS 343^PRO 378^ASN

1.2.1.3, 1.2.1.8

cytoplasm

oxidation reduction
metabolic process

oxidoreductase activity
betaine-aldehyde dehydrogenase activity
aldehyde dehydrogenase (NAD) activity

1zpdE

[pdb]

1.97446
0.00255396

62^ARG 65^GLY 91^ASN 219^LYS 224^GLY 285^PRO

4.1.1.1

metal ion binding
carboxy-lyase activity
lyase activity
magnesium ion binding
pyruvate decarboxylase activity
thiamin pyrophosphate binding
transferase activity
catalytic activity

1t3qE

[pdb]

1.97779
0.00262017

146^VAL 153^LYS 156^TYR 164^GLU 364^LYS 366^PRO

0.0.0.0

oxidoreductase activity
electron carrier activity
FAD binding
oxidoreductase activity
electron carrier activity
catalytic activity
iron-sulfur cluster binding
metal ion binding
oxidoreductase activity
electron carrier activity
iron ion binding
2 iron
2 sulfur cluster binding

1xa0B

[pdb]

1.98288
0.00262053

43^ASN 160^GLY 308^PRO 312^LYS 317^GLY 322^ARG

0.0.0.0

1qkiD

[pdb]

1.98331
0.00268938

359^GLY 363^ASN 366^LYS 396^PRO 487^ARG 488^GLY

1.1.1.49

intracellular membrane-bounded organelle
centrosome
cytoplasm
cytosol
internal side of plasma membrane

oxidation reduction
glucose metabolic process
carbohydrate metabolic process
metabolic process
erythrocyte development
regulation of multicellular organism growth
interleukin-12 production
interleukin-10 production
pentose biosynthetic process
response to oxidative stress
glutathione metabolic process
NADP biosynthetic process
vasodilation by angiotensin involved in regulation of systemic arterial blood pressure
angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure
cytokine production
erythrocyte maturation
cellular response to oxidative stress
negative regulation of protein amino acid glutathionylation
NADPH regeneration
pentose-phosphate shunt
glucose 6-phosphate utilization
ribose phosphate biosynthetic process
lipid metabolic process
cholesterol biosynthetic process
pentose-phosphate shunt
oxidative branch

oxidoreductase activity
glucose-6-phosphate dehydrogenase activity
binding
catalytic activity
protein homodimerization activity
glucose binding
NADP or NADPH binding

1jqvA

[pdb]

1.98368
0.0026894

225^LYS 226^PRO 231^ASN 233^ARG 247^GLY 264^GLY

1.3.3.1

cytoplasm
cytoplasm

oxidation reduction
pyrimidine nucleotide biosynthetic process
metabolic process
UMP biosynthetic process
'de novo' pyrimidine base biosynthetic process
pyrimidine nucleotide biosynthetic process
metabolic process
UMP biosynthetic process
'de novo' pyrimidine base biosynthetic process
oxidation reduction

oxidoreductase activity
dihydroorotate oxidase activity
dihydroorotate dehydrogenase activity
catalytic activity
oxidoreductase activity
dihydroorotate oxidase activity
dihydroorotate dehydrogenase activity
catalytic activity

1yb5A

[pdb]

1.98555
0.00268954

170^ARG 173^GLY 192^ASN 293^GLY 296^LYS 297^PRO

1.6.5.5

cytoplasm

oxidation reduction
visual perception
metabolic process

oxidoreductase activity
NADPH:quinone reductase activity
zinc ion binding
binding
catalytic activity

3bohB

[pdb]

1.98625
0.00268959

79^ASN 80^ARG 81^GLY 130^GLY 198^PRO 199^LYS

0.0.0.0

2gw2A

[pdb]

1.99848
0.00283689

76^GLY 83^ASN 85^ARG 87^GLY 164^LYS 165^PRO

5.2.1.8

nuclear speck
nuclear matrix
nucleus
nucleoplasm

peptide binding
isomerase activity
peptidyl-prolyl cis-trans isomerase activity
cyclosporin A binding

protein folding
RNA splicing

1ul1Z

[pdb]

2.00141
0.00283712

28^TRP 77^LYS 80^LYS 81^CYS 332^ARG 334^GLY

DNA repair
DNA replication
phosphoinositide-mediated signaling
UV protection
double-strand break repair
base-excision repair
gap-filling
DNA replication
DNA repair
phosphoinositide-mediated signaling
nucleotide-excision repair
DNA gap filling
cell proliferation
regulation of DNA replication
intracellular protein transport
mismatch repair
DNA replication
removal of RNA primer

nucleus
DNA replication factor C complex
nucleus
nucleoplasm
PCNA complex
replication fork
nuclear lamina
cyclin-dependent protein kinase holoenzyme complex
mitochondrion

protein binding
ribonuclease H activity
5'-3' exonuclease activity
5'-flap endonuclease activity
DNA binding
hydrolase activity
exonuclease activity
endonuclease activity
nuclease activity
double-stranded DNA specific exodeoxyribonuclease activity
double-stranded DNA binding
damaged DNA binding
catalytic activity
flap endonuclease activity
manganese ion binding
magnesium ion binding
MutLalpha complex binding
protein binding
DNA binding
DNA polymerase processivity factor activity
purine-specific mismatch base pair DNA N-glycosylase activity
dinucleotide insertion or deletion binding
metal ion binding

1iokD

[pdb]

2.01498
0.00307901

33^PRO 34^LYS 452^ARG 457^ASN 459^GLY 462^GLY

0.0.0.0

ATP binding
nucleotide binding
protein binding
unfolded protein binding

cytoplasm

protein folding
cellular protein metabolic process
protein refolding

1tdhA

[pdb]

2.02168
0.00316348

2^PRO 53^GLY 54^LYS 134^GLY 169^ARG 172^ASN

4.2.99.18

cytoplasm
nucleus

hydrolase activity
acting on glycosyl bonds
protein C-terminus binding
lyase activity
hydrolase activity
catalytic activity
DNA binding
DNA-(apurinic or apyrimidinic site) lyase activity
hydrolase activity
hydrolyzing N-glycosyl compounds
zinc ion binding
damaged DNA binding
nucleic acid binding
DNA N-glycosylase activity

response to oxidative stress
negative regulation of nuclease activity
base-excision repair
metabolic process
response to DNA damage stimulus
DNA repair
nucleotide-excision repair

2r6iA

[pdb]

2.02246
0.00316355

0^GLY 62^LYS 63^PRO 95^ARG 98^ASN 103^GLY

0.0.0.0

1mroC

[pdb]

2.02739
0.00325104

151^ARG 152^GLY 188^LYS 189^ASN 192^GLY 198^PRO

2.8.4.1

methanogenesis
methanogenesis
methanogenesis

transferase activity
coenzyme-B sulfoethylthiotransferase activity
transferase activity
coenzyme-B sulfoethylthiotransferase activity
metal ion binding
transferase activity
nickel ion binding
coenzyme-B sulfoethylthiotransferase activity

1y7eA

[pdb]

2.02782
0.00325108

88^GLY 90^ASN 274^PRO 276^LYS 420^GLY 422^ARG

0.0.0.0

metal ion binding
hydrolase activity
zinc ion binding
metallopeptidase activity
peptidase activity
aminopeptidase activity
aminopeptidase activity
peptidase activity
metallopeptidase activity
zinc ion binding
hydrolase activity
metal ion binding
aminopeptidase activity
peptidase activity
metallopeptidase activity
zinc ion binding
hydrolase activity
metal ion binding

proteolysis
proteolysis
proteolysis

vacuole
vacuole
vacuole

1f76E

[pdb]

2.02851
0.00325114

90^ARG 119^GLY 141^GLY 142^LYS 143^ASN 147^PRO

1.3.3.1

oxidation reduction
pyrimidine nucleotide biosynthetic process
metabolic process
UMP biosynthetic process
'de novo' pyrimidine base biosynthetic process

oxidoreductase activity
dihydroorotate oxidase activity
dihydroorotate dehydrogenase activity
catalytic activity

plasma membrane
membrane

2ct6A

[pdb]

2.03263
0.00325152

59^ASN 62^PRO 64^LYS 79^GLY 81^ARG 84^GLY

SH3 domain binding

nucleus

2simA

[pdb]

2.03829
0.00334231

276^ARG 279^GLY 302^ASN 332^PRO 333^LYS 341^GLY

3.2.1.18

hydrolase activity
acting on glycosyl bonds
hydrolase activity
exo-alpha-sialidase activity

metabolic process
pathogenesis

2ccdB

[pdb]

2.03901
0.00334238

589^PRO 590^LYS 596^ASN 599^GLY 676^GLY 693^ARG

1.11.1.7, 1.11.1.6

heme binding
peroxidase activity
catalase activity
metal ion binding
oxidoreductase activity
iron ion binding

response to oxidative stress
oxidation reduction
hydrogen peroxide catabolic process

2g5wA

[pdb]

2.03903
0.00334238

131^LYS 132^PRO 200^GLY 202^ASN 204^ARG 210^GLY

1.3.1.42

12-oxophytodienoate reductase activity
oxidoreductase activity
FMN binding
catalytic activity

peroxisome

response to fungus
response to ozone
jasmonic acid biosynthetic process
oxidation reduction
oxylipin biosynthetic process
lipid biosynthetic process
fatty acid biosynthetic process
metabolic process

2qbwA

[pdb]

2.04658
0.00353341

13^VAL 15^HOH 17^HOH 25^HOH 43^PRO 46^LYS

0.0.0.0

cytoplasm
hemidesmosome
nucleus
basal plasma membrane
cell junction
basement membrane

integrin-mediated signaling pathway
intermediate filament cytoskeleton organization
establishment or maintenance of epithelial cell apical/basal polarity
basal protein localization
epidermal growth factor receptor signaling pathway
cell cycle
cell growth
cell adhesion
signal transduction

protein binding
ErbB-2 class receptor binding
integrin binding
structural constituent of cytoskeleton

2nteB

[pdb]

2.05798
0.00373819

627^GLY 656^GLY 659^ARG 663^ASN 669^PRO 670^LYS

0.0.0.0

BRCA1-A complex
BRCA1-BARD1 complex
ubiquitin ligase complex
nucleus
cytoplasm
intracellular

DNA repair
modification-dependent protein catabolic process
cell cycle arrest
positive regulation of apoptosis
regulation of phosphorylation
tissue homeostasis
protein ubiquitination
positive regulation of protein catabolic process
negative regulation of protein export from nucleus
negative regulation of mRNA 3'-end processing
response to DNA damage stimulus
negative regulation of apoptosis

ligase activity
RNA binding
protein binding
kinase binding
ubiquitin-protein ligase activity
protein heterodimerization activity
protein homodimerization activity
metal ion binding
zinc ion binding

2f2lA

[pdb]

2.06004
0.00373841

376^VAL 431^GLY 432^ILE 435^ILE 479^THR 484^GLU

integral to plasma membrane
membrane
integral to membrane
integral to membrane
membrane

peptidoglycan binding
N-acetylmuramoyl-L-alanine amidase activity
protein binding
Gram-negative bacterial binding
peptidoglycan receptor activity
N-acetylmuramoyl-L-alanine amidase activity
protein binding
protein dimerization activity
peptidoglycan binding
pattern recognition receptor activity

peptidoglycan catabolic process
innate immune response
immune response
antibacterial humoral response
innate immune response
immune response
peptidoglycan catabolic process
defense response to Gram-negative bacterium
antimicrobial humoral response
response to bacterium
positive regulation of antibacterial peptide biosynthetic process
phagocytosis

3dmcB

[pdb]

2.0603
0.00373844

103^PRO 105^LYS 107^ARG 127^GLY 130^GLY 133^ASN

0.0.0.0

2vy0A

[pdb]

2.06305
0.00373874

159^ASN 161^ARG 164^GLY 169^GLY 256^LYS 257^PRO

0.0.0.0

carbohydrate metabolic process

hydrolase activity
hydrolyzing O-glycosyl compounds

2dreB

[pdb]

2.06501
0.00384582

80^ASN 115^PRO 116^LYS 118^GLY 123^ARG 142^GLY

0.0.0.0

endopeptidase inhibitor activity

2yybB

[pdb]

2.06898
0.00384626

109^ASN 114^ARG 117^GLY 123^PRO 129^LYS 130^GLY

0.0.0.0

2v6oA

[pdb]

2.07126
0.00395509

413^GLY 414^ARG 435^ASN 437^GLY 438^LYS 439^PRO

0.0.0.0

cell redox homeostasis
oxidation reduction

cytoplasm

thioredoxin-disulfide reductase activity
FAD binding
oxidoreductase activity
protein disulfide oxidoreductase activity
electron carrier activity
NADP or NADPH binding

2i3yA

[pdb]

2.07426
0.00395542

105^GLY 106^LYS 109^PRO 164^GLY 180^ARG 182^ASN

1.11.1.9

extracellular region

oxidation reduction
lipid metabolic process
response to oxidative stress

oxidoreductase activity
peroxidase activity
glutathione peroxidase activity

1yzcA

[pdb]

2.07582
0.0039556

56^PRO 59^LYS 64^GLY 98^GLY 99^ARG 102^ASN

0.0.0.0

electron transport chain
transport

metal ion binding
iron ion binding
heme binding
electron carrier activity

periplasmic space

2ywoA

[pdb]

2.07722
0.00406607

133^GLY 134^ARG 136^ASN 140^LYS 142^PRO 172^GLY

0.0.0.0

cell redox homeostasis

isomerase activity
oxidoreductase activity
antioxidant activity

2f3oA

[pdb]

2.07777
0.00406613

590^PRO 591^LYS 593^GLY 594^ASN 667^ARG 669^GLY

0.0.0.0

cytoplasm

lyase activity
formate C-acetyltransferase activity
catalytic activity

metabolic process
glucose metabolic process

1n8wA

[pdb]

2.08963
0.00429853

296^LYS 375^GLY 384^PRO 387^ASN 389^ARG 391^GLY

2.3.3.9

cytoplasm

transferase activity
magnesium ion binding
malate synthase activity
catalytic activity

tricarboxylic acid cycle
glyoxylate cycle

3f7sA

[pdb]

2.09197
0.00429881

90^ASN 91^ARG 93^GLY 102^GLY 140^LYS 141^PRO

0.0.0.0

1a65A

[pdb]

2.09304
0.00429894

175^ARG 179^GLY 262^PRO 264^LYS 268^GLY 278^ASN

0.0.0.0

metal ion binding
oxidoreductase activity
copper ion binding
laccase activity

oxidation reduction

2d3qB

[pdb]

2.09697
0.00442018

102^GLY 311^LYS 314^PRO 368^ARG 373^ASN 395^GLY

0.0.0.0

3c2uD

[pdb]

2.09764
0.00442026

419^ASN 493^PRO 496^LYS 503^ARG 506^GLY 510^GLY

0.0.0.0

carbohydrate metabolic process

hydrolase activity
hydrolyzing O-glycosyl compounds

1fj2B

[pdb]

2.09932
0.00442047

150^GLY 153^GLY 157^ARG 185^LYS 189^ASN 190^PRO

cytoplasm

fatty acid metabolic process
lipid metabolic process

hydrolase activity
lysophospholipase activity

2o7jA

[pdb]

2.10059
0.00442063

270^ASN 273^LYS 274^PRO 419^GLY 459^GLY 463^ARG

0.0.0.0

transport

transporter activity

2e9fA

[pdb]

2.10171
0.00454505

119^ARG 124^GLY 194^ASN 220^GLY 222^LYS 224^PRO

4.3.2.1

cellular amino acid biosynthetic process
arginine biosynthetic process
arginine biosynthetic process via ornithine

cytoplasm

lyase activity
argininosuccinate lyase activity
catalytic activity

2w0jA

[pdb]

2.10336
0.00454527

342^GLY 403^GLY 405^ASN 406^ARG 471^PRO 472^LYS

2.7.11.1

DNA damage response
signal transduction resulting in induction of apoptosis
DNA damage checkpoint
response to DNA damage stimulus
cell cycle
DNA damage response
signal transduction
protein amino acid phosphorylation

PML body
nucleus

protein binding
protein serine/threonine kinase activity
metal ion binding
transferase activity
kinase activity
ATP binding
magnesium ion binding
nucleotide binding
protein kinase activity

3eynA

[pdb]

2.10414
0.00454537

41^PRO 43^LYS 45^ASN 128^ARG 130^GLY 211^GLY

fatty acid metabolic process
lipid metabolic process
metabolic process

metal ion binding
ligase activity
ATP binding
magnesium ion binding
nucleotide binding
butyrate-CoA ligase activity
catalytic activity

mitochondrial matrix
mitochondrion

1kkoA

[pdb]

2.10492
0.00454547

76^GLY 78^GLY 80^ARG 281^LYS 282^PRO 311^ASN

0.0.0.0

lyase activity

2cdcA

[pdb]

2.10872
0.00467379

90^ARG 102^GLY 113^GLY 307^ASN 310^LYS 311^PRO

0.0.0.0

oxidation reduction
metabolic process

oxidoreductase activity
glucose 1-dehydrogenase activity
zinc ion binding
binding
catalytic activity

2jwnA

[pdb]

2.11126
0.00467413

43^ASN 47^GLY 77^PRO 78^LYS 104^GLY 105^ARG

biological_process

cytoplasm

nucleic acid binding
nucleotide binding
poly(A) RNA binding
RNA binding

3bs0A

[pdb]

2.11127
0.00467413

140^GLY 220^GLY 222^ARG 240^ASN 242^LYS 278^PRO

0.0.0.0

2avwB

[pdb]

2.1136
0.00467444

182^ASN 199^GLY 201^LYS 203^PRO 214^ARG 215^GLY

0.0.0.0

peptidase activity

2h3lB

[pdb]

2.1155
0.00480611

1342^GLY 1343^ARG 1345^ASN 1353^GLY 1371^PRO 1374^LYS

cytoplasm
hemidesmosome
nucleus
basal plasma membrane
cell junction
basement membrane

integrin-mediated signaling pathway
intermediate filament cytoskeleton organization
establishment or maintenance of epithelial cell apical/basal polarity
basal protein localization
epidermal growth factor receptor signaling pathway
cell cycle
cell growth
cell adhesion
signal transduction

protein binding
ErbB-2 class receptor binding
integrin binding
structural constituent of cytoskeleton

2gya2

[pdb]

2.11784
0.00480643

57^GLU 60^LYS 134^ALA 163^TYR 199^SER 200^ASP

rRNA binding
RNA binding
structural constituent of ribosome
protein binding
structural constituent of ribosome
protein binding
structural constituent of ribosome
protein binding
rRNA binding
RNA binding
structural constituent of ribosome
protein binding
rRNA binding
RNA binding
structural constituent of ribosome
protein binding
rRNA binding
RNA binding
structural constituent of ribosome
rRNA binding
RNA binding
structural constituent of ribosome
protein binding
structural constituent of ribosome
rRNA binding
RNA binding
structural constituent of ribosome
protein binding
rRNA binding
RNA binding
structural constituent of ribosome
protein binding
rRNA binding
RNA binding
transferase activity
structural constituent of ribosome
protein binding
structural constituent of ribosome
structural constituent of ribosome
rRNA binding
RNA binding
structural constituent of ribosome
rRNA binding
RNA binding
5S rRNA binding
structural constituent of ribosome
protein binding
RNA binding
tRNA binding
structural constituent of ribosome
rRNA binding
RNA binding
tRNA binding
structural constituent of ribosome
structural constituent of ribosome
rRNA binding
RNA binding
tRNA binding
structural constituent of ribosome
rRNA binding
RNA binding
nucleotide binding
protein binding
rRNA binding
RNA binding
tRNA binding
structural constituent of ribosome
rRNA binding
RNA binding
structural constituent of ribosome
rRNA binding
RNA binding
structural constituent of ribosome
protein binding
rRNA binding
RNA binding
structural constituent of ribosome
rRNA binding
RNA binding
structural constituent of ribosome
rRNA binding
RNA binding
tRNA binding
structural constituent of ribosome
protein binding
rRNA binding
RNA binding
structural constituent of ribosome
protein binding

ribonucleoprotein complex
ribosome
intracellular
ribonucleoprotein complex
ribosome
intracellular
ribonucleoprotein complex
ribosome
large ribosomal subunit
ribonucleoprotein complex
ribosome
intracellular
ribonucleoprotein complex
ribosome
large ribosomal subunit
intracellular
ribonucleoprotein complex
ribosome
intracellular
ribonucleoprotein complex
ribosome
intracellular
intracellular
ribonucleoprotein complex
ribosome
intracellular
ribonucleoprotein complex
ribosome
large ribosomal subunit
intracellular
ribonucleoprotein complex
ribosome
large ribosomal subunit
intracellular
ribonucleoprotein complex
ribosome
intracellular
ribonucleoprotein complex
ribosome
large ribosomal subunit
intracellular
ribonucleoprotein complex
ribosome
intracellular
ribonucleoprotein complex
ribosome
intracellular
ribonucleoprotein complex
ribosome
intracellular
ribonucleoprotein complex
ribosome
intracellular
ribonucleoprotein complex
ribosome
intracellular
ribonucleoprotein complex
ribosome
intracellular
ribonucleoprotein complex
ribosome
ribonucleoprotein complex
ribosome
intracellular
ribonucleoprotein complex
ribosome
intracellular
ribonucleoprotein complex
ribosome
intracellular
ribonucleoprotein complex
ribosome
intracellular
ribonucleoprotein complex
ribosome
large ribosomal subunit
intracellular
ribonucleoprotein complex
ribosome
large ribosomal subunit
intracellular
ribonucleoprotein complex
ribosome
intracellular

translation
translation
translation
translation
translation
translation
response to antibiotic
translation
regulation of transcription
translation
response to antibiotic
translation
translation
translation
translation
translation
translation
translation
translation
translation
translation
translation
translation
translation
translation
translation
ribosomal large subunit assembly
translation
regulation of translation
translation
RNA processing
response to antibiotic
regulation of translation
regulation of transcription
DNA-dependent
transcription termination
transcription
translation

3bocA

[pdb]

2.12041
0.00494181

289^ASN 290^ARG 291^GLY 340^GLY 408^PRO 409^LYS

0.0.0.0

1iaxB

[pdb]

2.12576
0.00494255

56^ASN 278^LYS 283^PRO 338^ARG 340^GLY 363^GLY

4.4.1.14

lyase activity
1-aminocyclopropane-1-carboxylate synthase activity
pyridoxal phosphate binding
transferase activity
transferring nitrogenous groups
catalytic activity

ripening
ethylene biosynthetic process
biosynthetic process

1ua4A

[pdb]

2.13873
0.00536228

109^ARG 111^GLY 377^ASN 432^PRO 433^LYS 437^GLY

2.7.1.147

cytoplasm

glycolysis
glucose metabolic process
carbohydrate metabolic process

metal ion binding
transferase activity
kinase activity
magnesium ion binding
ADP-specific glucokinase activity
phosphotransferase activity
alcohol group as acceptor
glucokinase activity

2gn2A

[pdb]

2.13976
0.00536243

20^ARG 23^GLY 64^ASN 156^PRO 157^LYS 161^GLY

4.3.1.19

lyase activity
catalytic activity
L-threonine ammonia-lyase activity
pyridoxal phosphate binding

metabolic process
cellular amino acid metabolic process

1pe4A

[pdb]

2.14311
0.00536292

5^PRO 9^ASN 12^LYS 58^GLY 63^GLY 66^ARG

extracellular region

ion channel inhibitor activity
sodium channel inhibitor activity

pathogenesis
defense response

2k46A

[pdb]

2.14334
0.00536296

15^ASN 18^GLY 31^LYS 33^PRO 45^GLY 65^ARG

carbohydrate binding

membrane
endoplasmic reticulum
endoplasmic reticulum membrane
integral to membrane

protein amino acid terminal N-glycosylation
carbohydrate metabolic process

1q1zA

[pdb]

2.14417
0.00536308

69^PRO 70^LYS 148^ASN 150^ARG 276^GLY 279^GLY

2.8.2.2

cytosol
cytoplasm

steroid metabolic process
lipid metabolic process

steroid sulfotransferase activity
transferase activity
alcohol sulfotransferase activity
sulfotransferase activity
protein binding

2v4jD

[pdb]

2.14457
0.00536314

165^ILE 168^GLU 170^PHE 172^ASP 211^PRO 213^ILE

1.8.99.3

4 iron
4 sulfur cluster binding
iron-sulfur cluster binding
metal ion binding
oxidoreductase activity
iron ion binding
heme binding
hydrogensulfite reductase activity
electron carrier activity
4 iron
4 sulfur cluster binding
iron-sulfur cluster binding
metal ion binding
oxidoreductase activity
iron ion binding
hydrogensulfite reductase activity
heme binding
electron carrier activity
oxidoreductase activity
hydrogensulfite reductase activity

cytoplasm

oxidation reduction
oxidation reduction
oxidation reduction

1rfeA

[pdb]

2.14744
0.00550958

106^GLY 122^LYS 123^PRO 130^ASN 132^ARG 134^GLY

0.0.0.0

FMN binding