The LabelHash Server

Top 100 matches

For each match you can click on the "[pdb]" link to download a PDB file with the matching chain aligned with the motif.
Download a zip file with PDB files for all the matches and the motif itself.

PDB ID	LRMSD / p-value	Matching Residues	EC	Gene Ontology annotations
1kpgB	[pdb]	0.0832184 6.55934e-05	17^ASP 72^GLY 74^GLY 75^TRP 76^GLY 200^PHE	2.1.1.79	cytoplasm cytoplasm	lipid biosynthetic process lipid biosynthetic process	transferase activity methyltransferase activity cyclopropane-fatty-acyl-phospholipid synthase activity transferase activity methyltransferase activity cyclopropane-fatty-acyl-phospholipid synthase activity
1tpyA	[pdb]	0.0949709 7.27558e-05	17^ASP 72^GLY 74^GLY 75^TRP 76^GLY 200^PHE	0.0.0.0		lipid biosynthetic process	transferase activity methyltransferase activity cyclopropane-fatty-acyl-phospholipid synthase activity
1kpiA	[pdb]	0.205384 0.000127917	25^ASP 80^GLY 82^GLY 83^TRP 84^GLY 215^PHE	2.1.1.79	cytoplasm	lipid biosynthetic process	transferase activity methyltransferase activity cyclopropane-fatty-acyl-phospholipid synthase activity
1l1eB	[pdb]	1.06623 0.000219926	17^ASP 72^GLY 74^GLY 75^TRP 76^GLY 200^PHE	0.0.0.0		lipid biosynthetic process	transferase activity cyclopropane-fatty-acyl-phospholipid synthase activity
2fk7A	[pdb]	1.35196 0.000411574	29^ASP 81^GLY 83^GLY 84^TRP 85^GLY 209^PHE	0.0.0.0		lipid biosynthetic process	transferase activity methyltransferase activity cyclopropane-fatty-acyl-phospholipid synthase activity
3f06A	[pdb]	1.37856 0.00046064	139^GLY 141^TRP 183^ASP 207^PHE 265^GLY 303^GLY	3.5.1.98	chromatin modification regulation of transcription DNA-dependent transcription chromatin assembly or disassembly negative regulation of transcription from RNA polymerase II promoter histone deacetylation regulation of transcription	nucleus histone deacetylase complex cytoplasm nuclear chromosome	transcription factor binding histone deacetylase activity hydrolase activity
2hhgA	[pdb]	1.3799 0.000460659	27^ASP 88^PHE 95^GLY 119^GLY 121^GLY 123^TRP	0.0.0.0
2id3A	[pdb]	1.41755 0.000533164	59^TRP 60^GLY 63^GLY 64^GLY 72^ASP 130^PHE	0.0.0.0		DNA binding transcription regulator activity transcription factor activity	regulation of transcription DNA-dependent transcription regulation of transcription
2rdyA	[pdb]	1.42988 0.000549435	621^ASP 626^TRP 629^GLY 638^PHE 682^GLY 689^GLY	0.0.0.0			catalytic activity
1n6fF	[pdb]	1.44894 0.00060198	208^GLY 966^ASP 988^TRP 989^GLY 1011^PHE 1021^GLY		cytoplasm	hydrolase activity serine-type peptidase activity peptidase activity protein binding	proteolysis
2yxvB	[pdb]	1.47772 0.000679755	67^TRP 68^GLY 155^GLY 197^ASP 210^PHE 218^GLY	0.0.0.0	metal ion binding oxidoreductase activity copper ion binding	oxidation reduction	periplasmic space
2fqgA	[pdb]	1.51627 0.000795744	67^TRP 68^GLY 155^GLY 197^ASP 210^PHE 218^GLY	0.0.0.0	metal ion binding oxidoreductase activity copper ion binding	oxidation reduction	periplasmic space
3bgtA	[pdb]	1.52806 0.000821526	27^PHE 107^GLY 108^GLY 112^TRP 113^GLY 235^ASP	4.1.1.4			carboxy-lyase activity lyase activity acetoacetate decarboxylase activity
1xqeA	[pdb]	1.53899 0.000875042	31^PHE 244^GLY 245^TRP 264^GLY 268^GLY 313^ASP	0.0.0.0	ammonia transporter activity ammonium transmembrane transporter activity	carbon dioxide transport ammonium transport transport	plasma membrane integral to membrane membrane
2o1oA	[pdb]	1.58295 0.00106708	76^GLY 95^ASP 101^GLY 102^TRP 161^PHE 223^GLY	0.0.0.0		isoprenoid biosynthetic process	transferase activity
1kb0A	[pdb]	1.62495 0.00126553	68^GLY 456^PHE 497^ASP 541^TRP 542^GLY 546^GLY		metal ion binding oxidoreductase activity calcium ion binding iron ion binding heme binding oxidoreductase activity acting on CH-OH group of donors electron carrier activity	oxidation reduction	periplasmic space outer membrane-bounded periplasmic space membrane
1t3tA	[pdb]	1.64658 0.00140795	305^TRP 369^GLY 372^GLY 373^GLY 473^ASP 1094^PHE	6.3.5.3	cytoplasm	ligase activity ATP binding phosphoribosylformylglycinamidine synthase activity catalytic activity nucleotide binding	purine nucleotide biosynthetic process 'de novo' IMP biosynthetic process glutamine metabolic process
1rwiB	[pdb]	1.65914 0.0015106	112^GLY 146^PHE 154^GLY 169^ASP 195^TRP 196^GLY	2.7.11.1		protein amino acid phosphorylation	transferase activity kinase activity ATP binding protein serine/threonine kinase activity nucleotide binding protein kinase activity
2fheB	[pdb]	1.66809 0.00156578	11^GLY 35^ASP 41^PHE 204^GLY 205^TRP 211^GLY	2.5.1.18		metabolic process	transferase activity glutathione transferase activity
1kkcX	[pdb]	1.67085 0.00156594	125^PHE 135^GLY 140^GLY 141^TRP 142^GLY 154^ASP	1.15.1.1	metal ion binding manganese ion binding oxidoreductase activity superoxide dismutase activity	mitochondrial matrix mitochondrion	oxidation reduction superoxide metabolic process
1jfrA	[pdb]	1.67874 0.00162367	38^PHE 94^ASP 129^GLY 134^GLY 155^GLY 156^TRP	0.0.0.0			hydrolase activity
2qzsA	[pdb]	1.68408 0.00168393	114^GLY 115^TRP 117^GLY 141^GLY 169^PHE 176^ASP	2.4.1.21		glycogen biosynthetic process glucan biosynthetic process biosynthetic process	transferase activity transferring glycosyl groups transferase activity starch synthase activity protein binding
2va1D	[pdb]	1.68541 0.00168402	19^ASP 25^PHE 49^GLY 50^GLY 54^TRP 73^GLY	0.0.0.0	cytoplasm	pyrimidine nucleotide biosynthetic process cellular amino acid biosynthetic process 'de novo' pyrimidine base biosynthetic process	transferase activity kinase activity ATP binding nucleotide binding UMP kinase activity uridylate kinase activity
2oz3B	[pdb]	1.70096 0.00181326	20^ASP 127^GLY 293^GLY 294^TRP 296^GLY 353^PHE	0.0.0.0		catalytic activity	cellular amino acid catabolic process metabolic process
1kitA	[pdb]	1.7158 0.00194975	361^GLY 362^TRP 364^GLY 390^ASP 440^PHE 479^GLY	3.2.1.18	extracellular region extracellular region	hydrolase activity acting on glycosyl bonds hydrolase activity calcium ion binding exo-alpha-sialidase activity hydrolase activity acting on glycosyl bonds hydrolase activity calcium ion binding exo-alpha-sialidase activity	metabolic process metabolic process
1a0eA	[pdb]	1.72827 0.00209668	138^TRP 183^GLY 292^GLY 333^GLY 338^ASP 362^PHE	5.3.1.5	carbohydrate metabolic process D-xylose metabolic process pentose-phosphate shunt	cytoplasm	xylose isomerase activity magnesium ion binding cobalt ion binding metal ion binding isomerase activity
1eg1C	[pdb]	1.73497 0.00217485	154^GLY 169^GLY 172^ASP 180^TRP 183^GLY 317^PHE	3.2.1.4	cellulose catabolic process metabolic process carbohydrate metabolic process polysaccharide catabolic process	extracellular region	hydrolase activity acting on glycosyl bonds hydrolase activity cellulase activity cellulose binding hydrolase activity hydrolyzing O-glycosyl compounds
2dtnB	[pdb]	1.73546 0.00217489	14^GLY 182^GLY 183^GLY 207^TRP 214^ASP 222^PHE	2.5.1.31		cell division peptidoglycan biosynthetic process regulation of cell shape cell cycle cell wall organization metabolic process	transferase activity transferring alkyl or aryl (other than methyl) groups transferase activity di-trans,poly-cis-decaprenylcistransferase activity
1o7dA	[pdb]	1.75128 0.00234107	153^GLY 154^GLY 155^TRP 159^ASP 175^GLY 218^PHE	3.2.1.24	lysosome	metabolic process mannose metabolic process carbohydrate metabolic process learning or memory	metal ion binding hydrolase activity acting on glycosyl bonds hydrolase activity zinc ion binding alpha-mannosidase activity carbohydrate binding mannosidase activity catalytic activity hydrolase activity hydrolyzing O-glycosyl compounds
2e8zB	[pdb]	1.75632 0.00242882	409^GLY 436^GLY 437^TRP 461^GLY 465^ASP 564^PHE	0.0.0.0		carbohydrate metabolic process metabolic process	cation binding hydrolase activity hydrolyzing O-glycosyl compounds catalytic activity hydrolase activity hydrolase activity acting on glycosyl bonds
1sgtA	[pdb]	1.7618 0.00242931	184^GLY 194^ASP 200^PHE 215^TRP 216^GLY 226^GLY	3.4.21.4		hydrolase activity serine-type peptidase activity peptidase activity serine-type endopeptidase activity catalytic activity	proteolysis
1u79B	[pdb]	1.7715 0.0026098	7^PHE 62^GLY 70^TRP 73^GLY 76^GLY 122^ASP	5.2.1.8	chloroplast thylakoid lumen plastid chloroplast thylakoid lumen thylakoid	peptidyl-prolyl cis-trans isomerase activity isomerase activity	protein folding
1ub2A	[pdb]	1.77682 0.0026103	115^PHE 123^ASP 277^GLY 282^GLY 291^GLY 292^TRP	1.11.1.6, 1.11.1.7		metal ion binding oxidoreductase activity iron ion binding peroxidase activity catalase activity heme binding	oxidation reduction hydrogen peroxide catabolic process response to oxidative stress
1ua7A	[pdb]	1.78049 0.00270465	269^ASP 280^TRP 303^PHE 310^GLY 311^GLY 313^GLY	3.2.1.1	extracellular region	metabolic process carbohydrate metabolic process	metal ion binding hydrolase activity acting on glycosyl bonds hydrolase activity calcium ion binding alpha-amylase activity cation binding catalytic activity
3gpdR	[pdb]	1.78261 0.00270486	34^ASP 86^TRP 87^GLY 101^PHE 113^GLY 114^GLY	1.2.1.12	glycolysis oxidation reduction metabolic process glucose metabolic process	perinuclear region of cytoplasm cytoplasm membrane	protein binding glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) activity oxidoreductase activity NAD or NADH binding glyceraldehyde-3-phosphate dehydrogenase activity binding catalytic activity
2d5jA	[pdb]	1.78303 0.0027049	41^ASP 45^GLY 47^TRP 49^GLY 81^PHE 90^GLY		cytoplasm	hydrolase activity catalytic activity hydrolase activity acting on glycosyl bonds	metabolic process carbohydrate metabolic process polysaccharide catabolic process
1vrqB	[pdb]	1.78803 0.00280277	54^ALA 55^GLU 58^VAL 59^HIS 173^ILE 357^PHE	0.0.0.0	cytoplasm	oxidoreductase activity electron carrier activity sarcosine oxidase activity binding aminomethyltransferase activity catalytic activity oxidoreductase activity sarcosine oxidase activity sarcosine oxidase activity	tetrahydrofolate metabolic process metabolic process glycine catabolic process oxidation reduction tetrahydrofolate metabolic process tetrahydrofolate metabolic process
2ps2C	[pdb]	1.78981 0.00280295	49^GLY 50^TRP 51^GLY 56^PHE 275^GLY 302^ASP	0.0.0.0		catalytic activity	metabolic process
1wueB	[pdb]	1.79288 0.00290405	2098^TRP 2100^GLY 2239^ASP 2268^GLY 2269^GLY 2279^PHE	0.0.0.0		catalytic activity	metabolic process
2fr1A	[pdb]	1.79503 0.00290427	1593^TRP 1594^GLY 1596^GLY 1798^PHE 1812^GLY 1821^ASP	2.3.1.94		antibiotic biosynthetic process biosynthetic process metabolic process	transferase activity acyltransferase activity catalytic activity erythronolide synthase activity cofactor binding phosphopantetheine binding oxidoreductase activity binding acyl carrier activity
3beuA	[pdb]	1.79837 0.00290462	184^GLY 194^ASP 200^PHE 215^TRP 216^GLY 226^GLY	3.4.21.4		hydrolase activity serine-type peptidase activity peptidase activity serine-type endopeptidase activity catalytic activity	proteolysis
1o9bB	[pdb]	1.79923 0.00290471	108^GLY 110^GLY 120^PHE 254^ASP 261^TRP 263^GLY	1.1.1.282	cytoplasm cytoplasm	oxidation reduction aromatic amino acid family biosynthetic process cellular amino acid biosynthetic process metabolic process oxidation reduction aromatic amino acid family biosynthetic process cellular amino acid biosynthetic process metabolic process	oxidoreductase activity quinate/shikimate dehydrogenase activity binding shikimate 5-dehydrogenase activity catalytic activity quinate 5-dehydrogenase activity oxidoreductase activity quinate/shikimate dehydrogenase activity binding shikimate 5-dehydrogenase activity catalytic activity protein binding quinate 5-dehydrogenase activity
2gagB	[pdb]	1.80348 0.00300941	55^GLU 56^ARG 59^HIS 60^ALA 174^ARG 358^PHE	0.0.0.0	cytoplasm	electron carrier activity oxidoreductase activity oxidoreductase activity sarcosine oxidase activity sarcosine oxidase activity binding aminomethyltransferase activity catalytic activity sarcosine oxidase activity	tetrahydrofolate metabolic process metabolic process glycine catabolic process tetrahydrofolate metabolic process tetrahydrofolate metabolic process
2p9qB	[pdb]	1.80967 0.00311781	288^GLY 292^ASP 298^GLY 309^GLY 310^TRP 342^PHE	2.7.2.3	cytoplasm	phosphoglycerate kinase activity ATP binding transferase activity kinase activity nucleotide binding	phosphorylation glycolysis
2gbxC	[pdb]	1.80997 0.00311784	205^GLY 209^GLY 210^TRP 228^GLY 350^PHE 359^ASP	0.0.0.0		oxidation reduction cellular aromatic compound metabolic process aromatic compound catabolic process oxidation reduction cellular aromatic compound metabolic process	oxidoreductase activity acting on single donors with incorporation of molecular oxygen incorporation of two atoms of oxygen 2 iron 2 sulfur cluster binding oxidoreductase activity electron carrier activity iron ion binding oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen NADH or NADPH as one donor and incorporation of two atoms of oxygen into one donor metal ion binding iron-sulfur cluster binding oxidoreductase activity acting on single donors with incorporation of molecular oxygen incorporation of two atoms of oxygen catalytic activity
3cwvA	[pdb]	1.81414 0.00311831	39^ASP 66^PHE 85^GLY 94^GLY 96^GLY 97^TRP	0.0.0.0	ATP binding DNA topoisomerase (ATP-hydrolyzing) activity DNA binding nucleotide binding DNA topoisomerase activity isomerase activity	DNA topological change	chromosome
2e9aA	[pdb]	1.81745 0.00322992	27^GLY 196^GLY 197^GLY 221^TRP 228^ASP 236^PHE	2.5.1.31		cell division peptidoglycan biosynthetic process regulation of cell shape cell cycle cell wall organization metabolic process	transferase activity transferring alkyl or aryl (other than methyl) groups transferase activity di-trans,poly-cis-decaprenylcistransferase activity
3cn7A	[pdb]	1.81944 0.00323015	21^GLY 66^TRP 88^ASP 111^GLY 115^GLY 124^PHE	0.0.0.0			hydrolase activity
1wpxB	[pdb]	1.82459 0.00334376	597^ASP 688^TRP 689^GLY 696^GLY 698^GLY 713^PHE	0.0.0.0	cytoplasm fungal-type vacuole membrane fungal-type vacuole lumen vacuole endoplasmic reticulum cytoplasm fungal-type vacuole lumen fungal-type vacuole	regulation of proteolysis phytochelatin biosynthetic process vacuolar protein catabolic process proteolysis	serine-type endopeptidase inhibitor activity endopeptidase inhibitor activity peptidase inhibitor activity hydrolase activity peptidase activity carboxypeptidase activity glutathione gamma-glutamylcysteinyltransferase activity serine-type carboxypeptidase activity protein binding
1ipdA	[pdb]	1.82957 0.00334433	10^GLY 39^PHE 47^ASP 73^GLY 74^GLY 77^TRP	1.1.1.85	NAD or NADH binding metal ion binding manganese ion binding oxidoreductase activity magnesium ion binding 3-isopropylmalate dehydrogenase activity oxidoreductase activity acting on the CH-OH group of donors NAD or NADP as acceptor	cytoplasm	oxidation reduction leucine biosynthetic process branched chain family amino acid biosynthetic process cellular amino acid biosynthetic process metabolic process
1fiwA	[pdb]	1.83405 0.00345968	21^ASP 117^PHE 140^GLY 141^TRP 193^GLY 197^GLY	3.4.21.10	acrosomal vesicle	activation of adenylate cyclase activity penetration of zona pellucida acrosome reaction single fertilization proteolysis	drug binding fucose binding protein binding amidase activity mannose binding serine-type endopeptidase activity hydrolase activity serine-type peptidase activity peptidase activity catalytic activity
1yeyC	[pdb]	1.83827 0.00357857	14^PHE 22^GLY 29^ASP 193^GLY 194^TRP 353^GLY	0.0.0.0		catalytic activity	metabolic process
2gjxF	[pdb]	1.84415 0.0035793	293^SER 352^GLU 353^SER 380^LYS 405^GLU 410^ALA	3.2.1.52	hydrolase activity acting on glycosyl bonds hydrolase activity beta-N-acetylhexosaminidase activity protein heterodimerization activity cation binding catalytic activity protein binding hydrolase activity acting on glycosyl bonds hydrolase activity beta-N-acetylhexosaminidase activity protein heterodimerization activity protein homodimerization activity cation binding catalytic activity hydrolase activity hydrolyzing O-glycosyl compounds hydrolase activity hydrolyzing O-glycosyl compounds	lysosome membrane lysosome membrane acrosomal vesicle	metabolic process carbohydrate metabolic process neuromuscular process controlling balance neuromuscular process controlling posture myelination glycosaminoglycan metabolic process sexual reproduction lipid storage adult walking behavior locomotory behavior sensory perception of sound lysosome organization ganglioside catabolic process skeletal system development metabolic process carbohydrate metabolic process neuromuscular process neuromuscular process controlling balance oogenesis cellular protein metabolic process myelination regulation of cellular metabolic process glycosaminoglycan metabolic process sexual reproduction lipid storage oligosaccharide catabolic process phospholipid biosynthetic process male courtship behavior locomotory behavior sensory perception of sound penetration of zona pellucida single fertilization lysosome organization cellular calcium ion homeostasis ganglioside catabolic process glycosphingolipid metabolic process skeletal system development
1itxA	[pdb]	1.84454 0.00357934	280^ASP 337^PHE 341^GLY 342^TRP 359^GLY 363^GLY	3.2.1.14	extracellular region	hydrolase activity acting on glycosyl bonds hydrolase activity chitinase activity cation binding carbohydrate binding hydrolase activity hydrolyzing O-glycosyl compounds catalytic activity	metabolic process chitin catabolic process carbohydrate metabolic process polysaccharide catabolic process
2gjxA	[pdb]	1.84517 0.00370141	261^GLY 320^GLY 321^GLY 348^PHE 373^TRP 378^ASP	3.2.1.52	hydrolase activity acting on glycosyl bonds hydrolase activity beta-N-acetylhexosaminidase activity protein heterodimerization activity cation binding catalytic activity protein binding hydrolase activity acting on glycosyl bonds hydrolase activity beta-N-acetylhexosaminidase activity protein heterodimerization activity protein homodimerization activity cation binding catalytic activity hydrolase activity hydrolyzing O-glycosyl compounds hydrolase activity hydrolyzing O-glycosyl compounds	lysosome membrane lysosome membrane acrosomal vesicle	metabolic process carbohydrate metabolic process neuromuscular process controlling balance neuromuscular process controlling posture myelination glycosaminoglycan metabolic process sexual reproduction lipid storage adult walking behavior locomotory behavior sensory perception of sound lysosome organization ganglioside catabolic process skeletal system development metabolic process carbohydrate metabolic process neuromuscular process neuromuscular process controlling balance oogenesis cellular protein metabolic process myelination regulation of cellular metabolic process glycosaminoglycan metabolic process sexual reproduction lipid storage oligosaccharide catabolic process phospholipid biosynthetic process male courtship behavior locomotory behavior sensory perception of sound penetration of zona pellucida single fertilization lysosome organization cellular calcium ion homeostasis ganglioside catabolic process glycosphingolipid metabolic process skeletal system development
1btpA	[pdb]	1.84676 0.00370162	43^GLY 71^ASP 82^PHE 140^GLY 141^TRP 142^GLY	3.4.21.4	digestion proteolysis	extracellular region extracellular space	metal ion binding hydrolase activity serine-type peptidase activity peptidase activity calcium ion binding serine-type endopeptidase activity catalytic activity protein binding
1zyoA	[pdb]	1.84949 0.00370196	165^GLY 216^ASP 282^GLY 283^TRP 285^GLY 314^PHE	0.0.0.0			catalytic activity
2z5lA	[pdb]	1.8521 0.00370229	145^TRP 146^GLY 148^GLY 368^PHE 381^GLY 391^ASP	0.0.0.0		biosynthetic process metabolic process	cofactor binding phosphopantetheine binding transferase activity oxidoreductase activity binding catalytic activity acyl carrier activity
2z8fA	[pdb]	1.8552 0.00382832	213^GLY 217^GLY 218^TRP 233^ASP 241^PHE 311^GLY	0.0.0.0		transport	transporter activity
1yobA	[pdb]	1.85671 0.00382852	95^GLY 126^GLY 128^TRP 131^ASP 135^PHE 148^GLY			electron transport chain nitrogen fixation transport	oxidoreductase activity FMN binding electron carrier activity iron ion binding
3dc0A	[pdb]	1.87094 0.00409274	269^ASP 280^TRP 303^PHE 310^GLY 311^GLY 313^GLY	0.0.0.0		carbohydrate metabolic process	cation binding catalytic activity
1y0gA	[pdb]	1.87471 0.00409326	28^ASP 59^PHE 144^GLY 148^TRP 149^GLY 150^GLY				periplasmic space
1zoiA	[pdb]	1.87574 0.00423018	30^GLY 31^TRP 71^ASP 95^GLY 99^GLY 208^PHE	0.0.0.0			hydrolase activity
1a88A	[pdb]	1.87656 0.00423029	29^GLY 30^TRP 70^ASP 94^GLY 98^GLY 207^PHE	1.11.1.10		catalytic activity hydrolase activity chloride ion binding oxidoreductase activity peroxidase activity chloride peroxidase activity	oxidation reduction
3c3yA	[pdb]	1.88035 0.00423082	154^ASP 184^TRP 185^GLY 227^GLY 229^GLY 232^PHE	0.0.0.0			transferase activity methyltransferase activity caffeoyl-CoA O-methyltransferase activity O-methyltransferase activity
3c8oB	[pdb]	1.88813 0.0043706	26^PHE 33^GLY 56^GLY 87^TRP 89^GLY 106^ASP			regulation of RNA metabolic process	ribonuclease inhibitor activity
1a8sA	[pdb]	1.89085 0.00451159	27^GLY 28^TRP 68^ASP 92^GLY 96^GLY 205^PHE	1.11.1.10		catalytic activity hydrolase activity chloride ion binding oxidoreductase activity peroxidase activity chloride peroxidase activity	oxidation reduction
1mg5B	[pdb]	1.90706 0.00480683	2^PHE 87^ASP 123^TRP 129^GLY 131^GLY 174^GLY	1.1.1.1	alcohol catabolic process oxidation reduction metabolic process alcohol metabolic process behavioral response to ethanol	alcohol dehydrogenase (NAD) activity oxidoreductase activity binding catalytic activity	cellular_component lipid particle
1r76A	[pdb]	1.91067 0.00480738	291^GLY 293^GLY 343^GLY 346^TRP 383^ASP 389^PHE	0.0.0.0			lyase activity
2ghsA	[pdb]	1.91234 0.00480764	24^PHE 236^TRP 237^GLY 239^GLY 242^ASP 258^GLY	0.0.0.0
1dx9A	[pdb]	1.91633 0.00496063	87^GLY 118^GLY 120^TRP 123^ASP 127^PHE 140^GLY			FMN binding protein binding electron carrier activity oxidoreductase activity oxidoreductase activity FMN binding electron carrier activity	oxidation reduction cellular response to iron ion starvation electron transport chain transport electron transport chain transport
3dcmX	[pdb]	1.91691 0.00496072	109^PHE 141^GLY 143^GLY 144^TRP 145^GLY 148^ASP
2ecfA	[pdb]	1.92037 0.0051177	541^ASP 556^PHE 608^GLY 609^TRP 613^GLY 630^GLY	0.0.0.0	membrane	proteolysis	serine-type peptidase activity
1iryA	[pdb]	1.92073 0.00511776	21^GLY 32^TRP 34^GLY 36^GLY 119^ASP 133^PHE	0.0.0.0	cytoplasm	hydrolase activity GTPase activity 8-oxo-7,8-dihydroguanine triphosphatase activity protein binding	response to oxidative stress DNA repair
1lquB	[pdb]	1.92209 0.00511798	47^GLY 105^GLY 109^ASP 138^PHE 358^GLY 359^TRP	1.18.1.2		oxidation reduction	oxidoreductase activity ferredoxin-NADP+ reductase activity electron carrier activity
1op2A	[pdb]	1.9242 0.00511832	23^ASP 29^PHE 140^GLY 141^TRP 142^GLY 197^GLY		extracellular region	hydrolase activity serine-type peptidase activity peptidase activity serine-type endopeptidase activity catalytic activity	pathogenesis proteolysis
2vrkA	[pdb]	1.92793 0.00527951	131^GLY 178^TRP 179^GLY 181^GLY 191^ASP 196^PHE	0.0.0.0		hydrolase activity acting on glycosyl bonds hydrolase activity alpha-N-arabinofuranosidase activity	metabolic process L-arabinose metabolic process
2z3zA	[pdb]	1.92794 0.00527951	538^ASP 549^PHE 601^GLY 602^TRP 623^GLY 626^GLY	0.0.0.0	aminopeptidase activity serine-type peptidase activity	membrane	proteolysis
1yiqA	[pdb]	1.92823 0.00527956	61^GLY 495^ASP 539^TRP 540^GLY 618^GLY 683^PHE	0.0.0.0	heme binding oxidoreductase activity acting on CH-OH group of donors electron carrier activity calcium ion binding iron ion binding	membrane	oxidation reduction
2iucA	[pdb]	1.93136 0.00528008	44^GLY 46^GLY 83^ASP 91^PHE 260^TRP 261^GLY	0.0.0.0		metabolic process	phosphatase activity catalytic activity
2nymF	[pdb]	1.93303 0.00528036	57^ASP 82^PHE 168^GLY 169^GLY 200^TRP 217^GLY	3.1.3.16	protein phosphatase type 2A complex nucleus membrane soluble fraction soluble fraction protein phosphatase type 2A complex membrane mitochondrion cytosol nucleus microtubule cytoskeleton chromosome centromeric region spindle nucleus microtubule cytoskeleton cytosol mitochondrion protein phosphatase type 2A complex cytoplasm plasma membrane	protein phosphatase type 2A regulator activity protein binding binding metal ion binding protein heterodimerization activity protein binding antigen binding protein phosphatase type 2A regulator activity binding protein heterodimerization activity manganese ion binding hydrolase activity iron ion binding phosphoprotein phosphatase activity protein binding	signal transduction regulation of cell adhesion regulation of Wnt receptor signaling pathway regulation of DNA replication RNA splicing ceramide metabolic process regulation of DNA replication mesoderm development negative regulation of cell growth regulation of growth second-messenger-mediated signaling protein complex assembly negative regulation of tyrosine phosphorylation of Stat3 protein inactivation of MAPK activity regulation of cell differentiation RNA splicing regulation of transcription induction of apoptosis ceramide metabolic process response to organic substance protein amino acid dephosphorylation proteasomal ubiquitin-dependent protein catabolic process regulation of cell differentiation negative regulation of cell growth regulation of transcription negative regulation of tyrosine phosphorylation of Stat3 protein regulation of growth regulation of cell adhesion regulation of Wnt receptor signaling pathway second-messenger-mediated signaling response to organic substance induction of apoptosis protein amino acid dephosphorylation inactivation of MAPK activity
1hl9B	[pdb]	1.93777 0.00544601	35^TRP 36^GLY 130^ASP 142^PHE 326^GLY 329^GLY	0.0.0.0		cation binding alpha-L-fucosidase activity catalytic activity	fucose metabolic process carbohydrate metabolic process
1elvA	[pdb]	1.9379 0.00544603	417^PHE 426^GLY 430^ASP 554^GLY 555^TRP 556^GLY	3.4.21.42	extracellular region	innate immune response complement activation classical pathway immune response proteolysis	metal ion binding hydrolase activity serine-type peptidase activity peptidase activity calcium ion binding serine-type endopeptidase activity catalytic activity
2puhA	[pdb]	1.94193 0.00544671	20^PHE 83^ASP 87^GLY 114^GLY 139^GLY 216^TRP	3.7.1.8		aromatic compound catabolic process	catalytic activity 2-hydroxy-6-ketonona-2,4-dienedoic acid hydrolase activity 2,6-dioxo-6-phenylhexa-3-enoate hydrolase activity hydrolase activity hydrolase activity acting on acid carbon-carbon bonds in ketonic substances
1q5xA	[pdb]	1.9424 0.00544679	26^PHE 33^GLY 56^GLY 87^TRP 89^GLY 106^ASP			regulation of RNA metabolic process	ribonuclease inhibitor activity
2pz1A	[pdb]	1.9426 0.00544682	234^GLY 239^GLY 241^GLY 242^TRP 521^PHE 539^ASP	0.0.0.0	cellular_component cytoplasm cell projection membrane plasma membrane intracellular	intracellular signaling cascade regulation of Rho protein signal transduction	protein domain specific binding Rho guanyl-nucleotide exchange factor activity guanyl-nucleotide exchange factor activity protein binding
1qutA	[pdb]	1.94896 0.00561495	166^GLY 199^PHE 208^ASP 215^GLY 222^GLY 247^TRP		cell outer membrane membrane plasma membrane	cell wall organization	lyase activity carbon-oxygen lyase activity acting on polysaccharides
1xkvA	[pdb]	1.94952 0.00561505	351^GLY 430^GLY 431^GLY 467^PHE 489^TRP 496^ASP	4.1.1.49	calcium ion binding metal ion binding carboxy-lyase activity lyase activity ATP binding nucleotide binding phosphoenolpyruvate carboxykinase (ATP) activity purine nucleotide binding phosphoenolpyruvate carboxykinase activity	cytoplasm	gluconeogenesis
2g6wA	[pdb]	1.95015 0.00561516	105^PHE 204^ASP 210^GLY 213^GLY 218^GLY 221^TRP	2.3.1.47		biotin biosynthetic process biosynthetic process metabolic process	transferase activity 8-amino-7-oxononanoate synthase activity pyridoxal phosphate binding transferase activity transferring nitrogenous groups catalytic activity
1tz9B	[pdb]	1.95224 0.00578482	3^TRP 4^GLY 28^GLY 63^GLY 244^PHE 317^ASP	4.2.1.8		glucuronate catabolic process	lyase activity mannonate dehydratase activity
1sg3B	[pdb]	1.95252 0.00578487	216^GLY 234^TRP 265^ASP 276^PHE 333^GLY 334^GLY	3.5.3.4		hydrolase activity allantoicase activity protein binding	purine base metabolic process allantoin catabolic process
1cx8D	[pdb]	1.95679 0.00578562	184^ASP 306^GLY 316^PHE 453^TRP 456^GLY 462^GLY		cellular iron ion homeostasis endocytosis interspecies interaction between organisms	membrane extracellular region melanosome plasma membrane integral to membrane integral to plasma membrane endosome cytoplasmic membrane-bounded vesicle perinuclear region of cytoplasm	transferrin receptor activity receptor activity
1a0cA	[pdb]	1.95916 0.00595988	187^TRP 188^GLY 189^GLY 192^GLY 245^ASP 252^PHE	5.3.1.5	D-xylose metabolic process pentose-phosphate shunt carbohydrate metabolic process	cobalt ion binding metal ion binding isomerase activity xylose isomerase activity magnesium ion binding	cytoplasm
1pq7A	[pdb]	1.96078 0.00596017	26^ASP 29^PHE 137^GLY 138^TRP 139^GLY 197^GLY	3.4.21.4	extracellular region	hydrolase activity serine-type peptidase activity peptidase activity serine-type endopeptidase activity catalytic activity	proteolysis
1xvyA	[pdb]	1.96187 0.00596037	95^TRP 97^GLY 224^PHE 229^GLY 231^GLY 290^ASP		iron ion transport ion transport transport	metal ion binding iron ion binding transporter activity	periplasmic space
2iouD	[pdb]	1.96221 0.00596043	214^VAL 304^ASP 342^ILE 343^GLU 345^GLY 364^ALA	0.0.0.0	cell outer membrane membrane plasma membrane outer membrane	pathogenesis cell adhesion	protein binding
1fwiC	[pdb]	1.96716 0.00613987	137^TRP 158^GLY 160^GLY 164^GLY 271^PHE 360^ASP	3.5.1.5	cytoplasm cytoplasm cytoplasm	metal ion binding hydrolase activity nickel ion binding urease activity hydrolase activity acting on carbon-nitrogen (but not peptide) bonds hydrolase activity urease activity nickel ion binding hydrolase activity urease activity nickel ion binding	urea metabolic process nitrogen compound metabolic process nitrogen compound metabolic process urea metabolic process nitrogen compound metabolic process
1q3xA	[pdb]	1.96816 0.00614006	572^GLY 573^TRP 574^GLY 589^ASP 634^GLY 648^PHE	3.4.21.104	extracellular region	innate immune response complement activation classical pathway immune response complement activation lectin pathway complement activation proteolysis	protein binding calcium-dependent protein binding metal ion binding hydrolase activity serine-type peptidase activity peptidase activity calcium ion binding serine-type endopeptidase activity catalytic activity
1zatA	[pdb]	1.9714 0.00614065	348^ASP 371^GLY 382^PHE 434^TRP 438^GLY 441^GLY	0.0.0.0
2z37B	[pdb]	1.97545 0.00632482	206^PHE 216^GLY 217^TRP 219^GLY 223^GLY 360^ASP	0.0.0.0		cell wall macromolecule catabolic process chitin catabolic process	chitin binding chitinase activity

PDB ID

LRMSD /
p-value

Matching Residues

Gene Ontology annotations

Biological Process

Cellular Component

Molecular Function

1kpgB

[pdb]

0.0832184
6.55934e-05

17^ASP 72^GLY 74^GLY 75^TRP 76^GLY 200^PHE

2.1.1.79

cytoplasm
cytoplasm

lipid biosynthetic process
lipid biosynthetic process

transferase activity
methyltransferase activity
cyclopropane-fatty-acyl-phospholipid synthase activity
transferase activity
methyltransferase activity
cyclopropane-fatty-acyl-phospholipid synthase activity

1tpyA

[pdb]

0.0949709
7.27558e-05

17^ASP 72^GLY 74^GLY 75^TRP 76^GLY 200^PHE

0.0.0.0

lipid biosynthetic process

transferase activity
methyltransferase activity
cyclopropane-fatty-acyl-phospholipid synthase activity

1kpiA

[pdb]

0.205384
0.000127917

25^ASP 80^GLY 82^GLY 83^TRP 84^GLY 215^PHE

2.1.1.79

cytoplasm

lipid biosynthetic process

transferase activity
methyltransferase activity
cyclopropane-fatty-acyl-phospholipid synthase activity

1l1eB

[pdb]

1.06623
0.000219926

17^ASP 72^GLY 74^GLY 75^TRP 76^GLY 200^PHE

0.0.0.0

lipid biosynthetic process

transferase activity
cyclopropane-fatty-acyl-phospholipid synthase activity

2fk7A

[pdb]

1.35196
0.000411574

29^ASP 81^GLY 83^GLY 84^TRP 85^GLY 209^PHE

0.0.0.0

lipid biosynthetic process

transferase activity
methyltransferase activity
cyclopropane-fatty-acyl-phospholipid synthase activity

3f06A

[pdb]

1.37856
0.00046064

139^GLY 141^TRP 183^ASP 207^PHE 265^GLY 303^GLY

3.5.1.98

chromatin modification
regulation of transcription
DNA-dependent
transcription
chromatin assembly or disassembly
negative regulation of transcription from RNA polymerase II promoter
histone deacetylation
regulation of transcription

nucleus
histone deacetylase complex
cytoplasm
nuclear chromosome

transcription factor binding
histone deacetylase activity
hydrolase activity

2hhgA

[pdb]

1.3799
0.000460659

27^ASP 88^PHE 95^GLY 119^GLY 121^GLY 123^TRP

0.0.0.0

2id3A

[pdb]

1.41755
0.000533164

59^TRP 60^GLY 63^GLY 64^GLY 72^ASP 130^PHE

0.0.0.0

DNA binding
transcription regulator activity
transcription factor activity

regulation of transcription
DNA-dependent
transcription
regulation of transcription

2rdyA

[pdb]

1.42988
0.000549435

621^ASP 626^TRP 629^GLY 638^PHE 682^GLY 689^GLY

0.0.0.0

catalytic activity

1n6fF

[pdb]

1.44894
0.00060198

208^GLY 966^ASP 988^TRP 989^GLY 1011^PHE 1021^GLY

cytoplasm

hydrolase activity
serine-type peptidase activity
peptidase activity
protein binding

proteolysis

2yxvB

[pdb]

1.47772
0.000679755

67^TRP 68^GLY 155^GLY 197^ASP 210^PHE 218^GLY

0.0.0.0

metal ion binding
oxidoreductase activity
copper ion binding

oxidation reduction

periplasmic space

2fqgA

[pdb]

1.51627
0.000795744

67^TRP 68^GLY 155^GLY 197^ASP 210^PHE 218^GLY

0.0.0.0

metal ion binding
oxidoreductase activity
copper ion binding

oxidation reduction

periplasmic space

3bgtA

[pdb]

1.52806
0.000821526

27^PHE 107^GLY 108^GLY 112^TRP 113^GLY 235^ASP

4.1.1.4

carboxy-lyase activity
lyase activity
acetoacetate decarboxylase activity

1xqeA

[pdb]

1.53899
0.000875042

31^PHE 244^GLY 245^TRP 264^GLY 268^GLY 313^ASP

0.0.0.0

ammonia transporter activity
ammonium transmembrane transporter activity

carbon dioxide transport
ammonium transport
transport

plasma membrane
integral to membrane
membrane

2o1oA

[pdb]

1.58295
0.00106708

76^GLY 95^ASP 101^GLY 102^TRP 161^PHE 223^GLY

0.0.0.0

isoprenoid biosynthetic process

transferase activity

1kb0A

[pdb]

1.62495
0.00126553

68^GLY 456^PHE 497^ASP 541^TRP 542^GLY 546^GLY

metal ion binding
oxidoreductase activity
calcium ion binding
iron ion binding
heme binding
oxidoreductase activity
acting on CH-OH group of donors
electron carrier activity

oxidation reduction

periplasmic space
outer membrane-bounded periplasmic space
membrane

1t3tA

[pdb]

1.64658
0.00140795

305^TRP 369^GLY 372^GLY 373^GLY 473^ASP 1094^PHE

6.3.5.3

cytoplasm

ligase activity
ATP binding
phosphoribosylformylglycinamidine synthase activity
catalytic activity
nucleotide binding

purine nucleotide biosynthetic process
'de novo' IMP biosynthetic process
glutamine metabolic process

1rwiB

[pdb]

1.65914
0.0015106

112^GLY 146^PHE 154^GLY 169^ASP 195^TRP 196^GLY

2.7.11.1

protein amino acid phosphorylation

transferase activity
kinase activity
ATP binding
protein serine/threonine kinase activity
nucleotide binding
protein kinase activity

2fheB

[pdb]

1.66809
0.00156578

11^GLY 35^ASP 41^PHE 204^GLY 205^TRP 211^GLY

2.5.1.18

metabolic process

transferase activity
glutathione transferase activity

1kkcX

[pdb]

1.67085
0.00156594

125^PHE 135^GLY 140^GLY 141^TRP 142^GLY 154^ASP

1.15.1.1

metal ion binding
manganese ion binding
oxidoreductase activity
superoxide dismutase activity

mitochondrial matrix
mitochondrion

oxidation reduction
superoxide metabolic process

1jfrA

[pdb]

1.67874
0.00162367

38^PHE 94^ASP 129^GLY 134^GLY 155^GLY 156^TRP

0.0.0.0

hydrolase activity

2qzsA

[pdb]

1.68408
0.00168393

114^GLY 115^TRP 117^GLY 141^GLY 169^PHE 176^ASP

2.4.1.21

glycogen biosynthetic process
glucan biosynthetic process
biosynthetic process

transferase activity
transferring glycosyl groups
transferase activity
starch synthase activity
protein binding

2va1D

[pdb]

1.68541
0.00168402

19^ASP 25^PHE 49^GLY 50^GLY 54^TRP 73^GLY

0.0.0.0

cytoplasm

pyrimidine nucleotide biosynthetic process
cellular amino acid biosynthetic process
'de novo' pyrimidine base biosynthetic process

transferase activity
kinase activity
ATP binding
nucleotide binding
UMP kinase activity
uridylate kinase activity

2oz3B

[pdb]

1.70096
0.00181326

20^ASP 127^GLY 293^GLY 294^TRP 296^GLY 353^PHE

0.0.0.0

catalytic activity

cellular amino acid catabolic process
metabolic process

1kitA

[pdb]

1.7158
0.00194975

361^GLY 362^TRP 364^GLY 390^ASP 440^PHE 479^GLY

3.2.1.18

extracellular region
extracellular region

hydrolase activity
acting on glycosyl bonds
hydrolase activity
calcium ion binding
exo-alpha-sialidase activity
hydrolase activity
acting on glycosyl bonds
hydrolase activity
calcium ion binding
exo-alpha-sialidase activity

metabolic process
metabolic process

1a0eA

[pdb]

1.72827
0.00209668

138^TRP 183^GLY 292^GLY 333^GLY 338^ASP 362^PHE

5.3.1.5

carbohydrate metabolic process
D-xylose metabolic process
pentose-phosphate shunt

cytoplasm

xylose isomerase activity
magnesium ion binding
cobalt ion binding
metal ion binding
isomerase activity

1eg1C

[pdb]

1.73497
0.00217485

154^GLY 169^GLY 172^ASP 180^TRP 183^GLY 317^PHE

3.2.1.4

cellulose catabolic process
metabolic process
carbohydrate metabolic process
polysaccharide catabolic process

extracellular region

hydrolase activity
acting on glycosyl bonds
hydrolase activity
cellulase activity
cellulose binding
hydrolase activity
hydrolyzing O-glycosyl compounds

2dtnB

[pdb]

1.73546
0.00217489

14^GLY 182^GLY 183^GLY 207^TRP 214^ASP 222^PHE

2.5.1.31

cell division
peptidoglycan biosynthetic process
regulation of cell shape
cell cycle
cell wall organization
metabolic process

transferase activity
transferring alkyl or aryl (other than methyl) groups
transferase activity
di-trans,poly-cis-decaprenylcistransferase activity

1o7dA

[pdb]

1.75128
0.00234107

153^GLY 154^GLY 155^TRP 159^ASP 175^GLY 218^PHE

3.2.1.24

lysosome

metabolic process
mannose metabolic process
carbohydrate metabolic process
learning or memory

metal ion binding
hydrolase activity
acting on glycosyl bonds
hydrolase activity
zinc ion binding
alpha-mannosidase activity
carbohydrate binding
mannosidase activity
catalytic activity
hydrolase activity
hydrolyzing O-glycosyl compounds

2e8zB

[pdb]

1.75632
0.00242882

409^GLY 436^GLY 437^TRP 461^GLY 465^ASP 564^PHE

0.0.0.0

carbohydrate metabolic process
metabolic process

cation binding
hydrolase activity
hydrolyzing O-glycosyl compounds
catalytic activity
hydrolase activity
hydrolase activity
acting on glycosyl bonds

1sgtA

[pdb]

1.7618
0.00242931

184^GLY 194^ASP 200^PHE 215^TRP 216^GLY 226^GLY

3.4.21.4

hydrolase activity
serine-type peptidase activity
peptidase activity
serine-type endopeptidase activity
catalytic activity

proteolysis

1u79B

[pdb]

1.7715
0.0026098

7^PHE 62^GLY 70^TRP 73^GLY 76^GLY 122^ASP

5.2.1.8

chloroplast
thylakoid lumen
plastid
chloroplast thylakoid lumen
thylakoid

peptidyl-prolyl cis-trans isomerase activity
isomerase activity

protein folding

1ub2A

[pdb]

1.77682
0.0026103

115^PHE 123^ASP 277^GLY 282^GLY 291^GLY 292^TRP

1.11.1.6, 1.11.1.7

metal ion binding
oxidoreductase activity
iron ion binding
peroxidase activity
catalase activity
heme binding

oxidation reduction
hydrogen peroxide catabolic process
response to oxidative stress

1ua7A

[pdb]

1.78049
0.00270465

269^ASP 280^TRP 303^PHE 310^GLY 311^GLY 313^GLY

3.2.1.1

extracellular region

metabolic process
carbohydrate metabolic process

metal ion binding
hydrolase activity
acting on glycosyl bonds
hydrolase activity
calcium ion binding
alpha-amylase activity
cation binding
catalytic activity

3gpdR

[pdb]

1.78261
0.00270486

34^ASP 86^TRP 87^GLY 101^PHE 113^GLY 114^GLY

1.2.1.12

glycolysis
oxidation reduction
metabolic process
glucose metabolic process

perinuclear region of cytoplasm
cytoplasm
membrane

protein binding
glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) activity
oxidoreductase activity
NAD or NADH binding
glyceraldehyde-3-phosphate dehydrogenase activity
binding
catalytic activity

2d5jA

[pdb]

1.78303
0.0027049

41^ASP 45^GLY 47^TRP 49^GLY 81^PHE 90^GLY

cytoplasm

hydrolase activity
catalytic activity
hydrolase activity
acting on glycosyl bonds

metabolic process
carbohydrate metabolic process
polysaccharide catabolic process

1vrqB

[pdb]

1.78803
0.00280277

54^ALA 55^GLU 58^VAL 59^HIS 173^ILE 357^PHE

0.0.0.0

cytoplasm

oxidoreductase activity
electron carrier activity
sarcosine oxidase activity
binding
aminomethyltransferase activity
catalytic activity
oxidoreductase activity
sarcosine oxidase activity
sarcosine oxidase activity

tetrahydrofolate metabolic process
metabolic process
glycine catabolic process
oxidation reduction
tetrahydrofolate metabolic process
tetrahydrofolate metabolic process

2ps2C

[pdb]

1.78981
0.00280295

49^GLY 50^TRP 51^GLY 56^PHE 275^GLY 302^ASP

0.0.0.0

catalytic activity

metabolic process

1wueB

[pdb]

1.79288
0.00290405

2098^TRP 2100^GLY 2239^ASP 2268^GLY 2269^GLY 2279^PHE

0.0.0.0

catalytic activity

metabolic process

2fr1A

[pdb]

1.79503
0.00290427

1593^TRP 1594^GLY 1596^GLY 1798^PHE 1812^GLY 1821^ASP

2.3.1.94

antibiotic biosynthetic process
biosynthetic process
metabolic process

transferase activity
acyltransferase activity
catalytic activity
erythronolide synthase activity
cofactor binding
phosphopantetheine binding
oxidoreductase activity
binding
acyl carrier activity

3beuA

[pdb]

1.79837
0.00290462

184^GLY 194^ASP 200^PHE 215^TRP 216^GLY 226^GLY

3.4.21.4

hydrolase activity
serine-type peptidase activity
peptidase activity
serine-type endopeptidase activity
catalytic activity

proteolysis

1o9bB

[pdb]

1.79923
0.00290471

108^GLY 110^GLY 120^PHE 254^ASP 261^TRP 263^GLY

1.1.1.282

cytoplasm
cytoplasm

oxidation reduction
aromatic amino acid family biosynthetic process
cellular amino acid biosynthetic process
metabolic process
oxidation reduction
aromatic amino acid family biosynthetic process
cellular amino acid biosynthetic process
metabolic process

oxidoreductase activity
quinate/shikimate dehydrogenase activity
binding
shikimate 5-dehydrogenase activity
catalytic activity
quinate 5-dehydrogenase activity
oxidoreductase activity
quinate/shikimate dehydrogenase activity
binding
shikimate 5-dehydrogenase activity
catalytic activity
protein binding
quinate 5-dehydrogenase activity

2gagB

[pdb]

1.80348
0.00300941

55^GLU 56^ARG 59^HIS 60^ALA 174^ARG 358^PHE

0.0.0.0

cytoplasm

electron carrier activity
oxidoreductase activity
oxidoreductase activity
sarcosine oxidase activity
sarcosine oxidase activity
binding
aminomethyltransferase activity
catalytic activity
sarcosine oxidase activity

tetrahydrofolate metabolic process
metabolic process
glycine catabolic process
tetrahydrofolate metabolic process
tetrahydrofolate metabolic process

2p9qB

[pdb]

1.80967
0.00311781

288^GLY 292^ASP 298^GLY 309^GLY 310^TRP 342^PHE

2.7.2.3

cytoplasm

phosphoglycerate kinase activity
ATP binding
transferase activity
kinase activity
nucleotide binding

phosphorylation
glycolysis

2gbxC

[pdb]

1.80997
0.00311784

205^GLY 209^GLY 210^TRP 228^GLY 350^PHE 359^ASP

0.0.0.0

oxidation reduction
cellular aromatic compound metabolic process
aromatic compound catabolic process
oxidation reduction
cellular aromatic compound metabolic process

oxidoreductase activity
acting on single donors with incorporation of molecular oxygen
incorporation of two atoms of oxygen
2 iron
2 sulfur cluster binding
oxidoreductase activity
electron carrier activity
iron ion binding
oxidoreductase activity
acting on paired donors
with incorporation or reduction of molecular oxygen
oxidoreductase activity
acting on paired donors
with incorporation or reduction of molecular oxygen
NADH or NADPH as one donor
and incorporation of two atoms of oxygen into one donor
metal ion binding
iron-sulfur cluster binding
oxidoreductase activity
acting on single donors with incorporation of molecular oxygen
incorporation of two atoms of oxygen
catalytic activity

3cwvA

[pdb]

1.81414
0.00311831

39^ASP 66^PHE 85^GLY 94^GLY 96^GLY 97^TRP

0.0.0.0

ATP binding
DNA topoisomerase (ATP-hydrolyzing) activity
DNA binding
nucleotide binding
DNA topoisomerase activity
isomerase activity

DNA topological change

chromosome

2e9aA

[pdb]

1.81745
0.00322992

27^GLY 196^GLY 197^GLY 221^TRP 228^ASP 236^PHE

2.5.1.31

cell division
peptidoglycan biosynthetic process
regulation of cell shape
cell cycle
cell wall organization
metabolic process

transferase activity
transferring alkyl or aryl (other than methyl) groups
transferase activity
di-trans,poly-cis-decaprenylcistransferase activity

3cn7A

[pdb]

1.81944
0.00323015

21^GLY 66^TRP 88^ASP 111^GLY 115^GLY 124^PHE

0.0.0.0

hydrolase activity

1wpxB

[pdb]

1.82459
0.00334376

597^ASP 688^TRP 689^GLY 696^GLY 698^GLY 713^PHE

0.0.0.0

cytoplasm
fungal-type vacuole membrane
fungal-type vacuole lumen
vacuole
endoplasmic reticulum
cytoplasm
fungal-type vacuole lumen
fungal-type vacuole

regulation of proteolysis
phytochelatin biosynthetic process
vacuolar protein catabolic process
proteolysis

serine-type endopeptidase inhibitor activity
endopeptidase inhibitor activity
peptidase inhibitor activity
hydrolase activity
peptidase activity
carboxypeptidase activity
glutathione gamma-glutamylcysteinyltransferase activity
serine-type carboxypeptidase activity
protein binding

1ipdA

[pdb]

1.82957
0.00334433

10^GLY 39^PHE 47^ASP 73^GLY 74^GLY 77^TRP

1.1.1.85

NAD or NADH binding
metal ion binding
manganese ion binding
oxidoreductase activity
magnesium ion binding
3-isopropylmalate dehydrogenase activity
oxidoreductase activity
acting on the CH-OH group of donors
NAD or NADP as acceptor

cytoplasm

oxidation reduction
leucine biosynthetic process
branched chain family amino acid biosynthetic process
cellular amino acid biosynthetic process
metabolic process

1fiwA

[pdb]

1.83405
0.00345968

21^ASP 117^PHE 140^GLY 141^TRP 193^GLY 197^GLY

3.4.21.10

acrosomal vesicle

activation of adenylate cyclase activity
penetration of zona pellucida
acrosome reaction
single fertilization
proteolysis

drug binding
fucose binding
protein binding
amidase activity
mannose binding
serine-type endopeptidase activity
hydrolase activity
serine-type peptidase activity
peptidase activity
catalytic activity

1yeyC

[pdb]

1.83827
0.00357857

14^PHE 22^GLY 29^ASP 193^GLY 194^TRP 353^GLY

0.0.0.0

catalytic activity

metabolic process

2gjxF

[pdb]

1.84415
0.0035793

293^SER 352^GLU 353^SER 380^LYS 405^GLU 410^ALA

3.2.1.52

hydrolase activity
acting on glycosyl bonds
hydrolase activity
beta-N-acetylhexosaminidase activity
protein heterodimerization activity
cation binding
catalytic activity
protein binding
hydrolase activity
acting on glycosyl bonds
hydrolase activity
beta-N-acetylhexosaminidase activity
protein heterodimerization activity
protein homodimerization activity
cation binding
catalytic activity
hydrolase activity
hydrolyzing O-glycosyl compounds
hydrolase activity
hydrolyzing O-glycosyl compounds

lysosome
membrane
lysosome
membrane
acrosomal vesicle

metabolic process
carbohydrate metabolic process
neuromuscular process controlling balance
neuromuscular process controlling posture
myelination
glycosaminoglycan metabolic process
sexual reproduction
lipid storage
adult walking behavior
locomotory behavior
sensory perception of sound
lysosome organization
ganglioside catabolic process
skeletal system development
metabolic process
carbohydrate metabolic process
neuromuscular process
neuromuscular process controlling balance
oogenesis
cellular protein metabolic process
myelination
regulation of cellular metabolic process
glycosaminoglycan metabolic process
sexual reproduction
lipid storage
oligosaccharide catabolic process
phospholipid biosynthetic process
male courtship behavior
locomotory behavior
sensory perception of sound
penetration of zona pellucida
single fertilization
lysosome organization
cellular calcium ion homeostasis
ganglioside catabolic process
glycosphingolipid metabolic process
skeletal system development

1itxA

[pdb]

1.84454
0.00357934

280^ASP 337^PHE 341^GLY 342^TRP 359^GLY 363^GLY

3.2.1.14

extracellular region

hydrolase activity
acting on glycosyl bonds
hydrolase activity
chitinase activity
cation binding
carbohydrate binding
hydrolase activity
hydrolyzing O-glycosyl compounds
catalytic activity

metabolic process
chitin catabolic process
carbohydrate metabolic process
polysaccharide catabolic process

2gjxA

[pdb]

1.84517
0.00370141

261^GLY 320^GLY 321^GLY 348^PHE 373^TRP 378^ASP

3.2.1.52

hydrolase activity
acting on glycosyl bonds
hydrolase activity
beta-N-acetylhexosaminidase activity
protein heterodimerization activity
cation binding
catalytic activity
protein binding
hydrolase activity
acting on glycosyl bonds
hydrolase activity
beta-N-acetylhexosaminidase activity
protein heterodimerization activity
protein homodimerization activity
cation binding
catalytic activity
hydrolase activity
hydrolyzing O-glycosyl compounds
hydrolase activity
hydrolyzing O-glycosyl compounds

lysosome
membrane
lysosome
membrane
acrosomal vesicle

metabolic process
carbohydrate metabolic process
neuromuscular process controlling balance
neuromuscular process controlling posture
myelination
glycosaminoglycan metabolic process
sexual reproduction
lipid storage
adult walking behavior
locomotory behavior
sensory perception of sound
lysosome organization
ganglioside catabolic process
skeletal system development
metabolic process
carbohydrate metabolic process
neuromuscular process
neuromuscular process controlling balance
oogenesis
cellular protein metabolic process
myelination
regulation of cellular metabolic process
glycosaminoglycan metabolic process
sexual reproduction
lipid storage
oligosaccharide catabolic process
phospholipid biosynthetic process
male courtship behavior
locomotory behavior
sensory perception of sound
penetration of zona pellucida
single fertilization
lysosome organization
cellular calcium ion homeostasis
ganglioside catabolic process
glycosphingolipid metabolic process
skeletal system development

1btpA

[pdb]

1.84676
0.00370162

43^GLY 71^ASP 82^PHE 140^GLY 141^TRP 142^GLY

3.4.21.4

digestion
proteolysis

extracellular region
extracellular space

metal ion binding
hydrolase activity
serine-type peptidase activity
peptidase activity
calcium ion binding
serine-type endopeptidase activity
catalytic activity
protein binding

1zyoA

[pdb]

1.84949
0.00370196

165^GLY 216^ASP 282^GLY 283^TRP 285^GLY 314^PHE

0.0.0.0

catalytic activity

2z5lA

[pdb]

1.8521
0.00370229

145^TRP 146^GLY 148^GLY 368^PHE 381^GLY 391^ASP

0.0.0.0

biosynthetic process
metabolic process

cofactor binding
phosphopantetheine binding
transferase activity
oxidoreductase activity
binding
catalytic activity
acyl carrier activity

2z8fA

[pdb]

1.8552
0.00382832

213^GLY 217^GLY 218^TRP 233^ASP 241^PHE 311^GLY

0.0.0.0

transport

transporter activity

1yobA

[pdb]

1.85671
0.00382852

95^GLY 126^GLY 128^TRP 131^ASP 135^PHE 148^GLY

electron transport chain
nitrogen fixation
transport

oxidoreductase activity
FMN binding
electron carrier activity
iron ion binding

3dc0A

[pdb]

1.87094
0.00409274

269^ASP 280^TRP 303^PHE 310^GLY 311^GLY 313^GLY

0.0.0.0

carbohydrate metabolic process

cation binding
catalytic activity

1y0gA

[pdb]

1.87471
0.00409326

28^ASP 59^PHE 144^GLY 148^TRP 149^GLY 150^GLY

periplasmic space

1zoiA

[pdb]

1.87574
0.00423018

30^GLY 31^TRP 71^ASP 95^GLY 99^GLY 208^PHE

0.0.0.0

hydrolase activity

1a88A

[pdb]

1.87656
0.00423029

29^GLY 30^TRP 70^ASP 94^GLY 98^GLY 207^PHE

1.11.1.10

catalytic activity
hydrolase activity
chloride ion binding
oxidoreductase activity
peroxidase activity
chloride peroxidase activity

oxidation reduction

3c3yA

[pdb]

1.88035
0.00423082

154^ASP 184^TRP 185^GLY 227^GLY 229^GLY 232^PHE

0.0.0.0

transferase activity
methyltransferase activity
caffeoyl-CoA O-methyltransferase activity
O-methyltransferase activity

3c8oB

[pdb]

1.88813
0.0043706

26^PHE 33^GLY 56^GLY 87^TRP 89^GLY 106^ASP

regulation of RNA metabolic process

ribonuclease inhibitor activity

1a8sA

[pdb]

1.89085
0.00451159

27^GLY 28^TRP 68^ASP 92^GLY 96^GLY 205^PHE

1.11.1.10

catalytic activity
hydrolase activity
chloride ion binding
oxidoreductase activity
peroxidase activity
chloride peroxidase activity

oxidation reduction

1mg5B

[pdb]

1.90706
0.00480683

2^PHE 87^ASP 123^TRP 129^GLY 131^GLY 174^GLY

1.1.1.1

alcohol catabolic process
oxidation reduction
metabolic process
alcohol metabolic process
behavioral response to ethanol

alcohol dehydrogenase (NAD) activity
oxidoreductase activity
binding
catalytic activity

cellular_component
lipid particle

1r76A

[pdb]

1.91067
0.00480738

291^GLY 293^GLY 343^GLY 346^TRP 383^ASP 389^PHE

0.0.0.0

lyase activity

2ghsA

[pdb]

1.91234
0.00480764

24^PHE 236^TRP 237^GLY 239^GLY 242^ASP 258^GLY

0.0.0.0

1dx9A

[pdb]

1.91633
0.00496063

87^GLY 118^GLY 120^TRP 123^ASP 127^PHE 140^GLY

FMN binding
protein binding
electron carrier activity
oxidoreductase activity
oxidoreductase activity
FMN binding
electron carrier activity

oxidation reduction
cellular response to iron ion starvation
electron transport chain
transport
electron transport chain
transport

3dcmX

[pdb]

1.91691
0.00496072

109^PHE 141^GLY 143^GLY 144^TRP 145^GLY 148^ASP

2ecfA

[pdb]

1.92037
0.0051177

541^ASP 556^PHE 608^GLY 609^TRP 613^GLY 630^GLY

0.0.0.0

membrane

proteolysis

serine-type peptidase activity

1iryA

[pdb]

1.92073
0.00511776

21^GLY 32^TRP 34^GLY 36^GLY 119^ASP 133^PHE

0.0.0.0

cytoplasm

hydrolase activity
GTPase activity
8-oxo-7,8-dihydroguanine triphosphatase activity
protein binding

response to oxidative stress
DNA repair

1lquB

[pdb]

1.92209
0.00511798

47^GLY 105^GLY 109^ASP 138^PHE 358^GLY 359^TRP

1.18.1.2

oxidation reduction

oxidoreductase activity
ferredoxin-NADP+ reductase activity
electron carrier activity

1op2A

[pdb]

1.9242
0.00511832

23^ASP 29^PHE 140^GLY 141^TRP 142^GLY 197^GLY

extracellular region

hydrolase activity
serine-type peptidase activity
peptidase activity
serine-type endopeptidase activity
catalytic activity

pathogenesis
proteolysis

2vrkA

[pdb]

1.92793
0.00527951

131^GLY 178^TRP 179^GLY 181^GLY 191^ASP 196^PHE

0.0.0.0

hydrolase activity
acting on glycosyl bonds
hydrolase activity
alpha-N-arabinofuranosidase activity

metabolic process
L-arabinose metabolic process

2z3zA

[pdb]

1.92794
0.00527951

538^ASP 549^PHE 601^GLY 602^TRP 623^GLY 626^GLY

0.0.0.0

aminopeptidase activity
serine-type peptidase activity

membrane

proteolysis

1yiqA

[pdb]

1.92823
0.00527956

61^GLY 495^ASP 539^TRP 540^GLY 618^GLY 683^PHE

0.0.0.0

heme binding
oxidoreductase activity
acting on CH-OH group of donors
electron carrier activity
calcium ion binding
iron ion binding

membrane

oxidation reduction

2iucA

[pdb]

1.93136
0.00528008

44^GLY 46^GLY 83^ASP 91^PHE 260^TRP 261^GLY

0.0.0.0

metabolic process

phosphatase activity
catalytic activity

2nymF

[pdb]

1.93303
0.00528036

57^ASP 82^PHE 168^GLY 169^GLY 200^TRP 217^GLY

3.1.3.16

protein phosphatase type 2A complex
nucleus
membrane
soluble fraction
soluble fraction
protein phosphatase type 2A complex
membrane
mitochondrion
cytosol
nucleus
microtubule cytoskeleton
chromosome
centromeric region
spindle
nucleus
microtubule cytoskeleton
cytosol
mitochondrion
protein phosphatase type 2A complex
cytoplasm
plasma membrane

protein phosphatase type 2A regulator activity
protein binding
binding
metal ion binding
protein heterodimerization activity
protein binding
antigen binding
protein phosphatase type 2A regulator activity
binding
protein heterodimerization activity
manganese ion binding
hydrolase activity
iron ion binding
phosphoprotein phosphatase activity
protein binding

signal transduction
regulation of cell adhesion
regulation of Wnt receptor signaling pathway
regulation of DNA replication
RNA splicing
ceramide metabolic process
regulation of DNA replication
mesoderm development
negative regulation of cell growth
regulation of growth
second-messenger-mediated signaling
protein complex assembly
negative regulation of tyrosine phosphorylation of Stat3 protein
inactivation of MAPK activity
regulation of cell differentiation
RNA splicing
regulation of transcription
induction of apoptosis
ceramide metabolic process
response to organic substance
protein amino acid dephosphorylation
proteasomal ubiquitin-dependent protein catabolic process
regulation of cell differentiation
negative regulation of cell growth
regulation of transcription
negative regulation of tyrosine phosphorylation of Stat3 protein
regulation of growth
regulation of cell adhesion
regulation of Wnt receptor signaling pathway
second-messenger-mediated signaling
response to organic substance
induction of apoptosis
protein amino acid dephosphorylation
inactivation of MAPK activity

1hl9B

[pdb]

1.93777
0.00544601

35^TRP 36^GLY 130^ASP 142^PHE 326^GLY 329^GLY

0.0.0.0

cation binding
alpha-L-fucosidase activity
catalytic activity

fucose metabolic process
carbohydrate metabolic process

1elvA

[pdb]

1.9379
0.00544603

417^PHE 426^GLY 430^ASP 554^GLY 555^TRP 556^GLY

3.4.21.42

extracellular region

innate immune response
complement activation
classical pathway
immune response
proteolysis

metal ion binding
hydrolase activity
serine-type peptidase activity
peptidase activity
calcium ion binding
serine-type endopeptidase activity
catalytic activity

2puhA

[pdb]

1.94193
0.00544671

20^PHE 83^ASP 87^GLY 114^GLY 139^GLY 216^TRP

3.7.1.8

aromatic compound catabolic process

catalytic activity
2-hydroxy-6-ketonona-2,4-dienedoic acid hydrolase activity
2,6-dioxo-6-phenylhexa-3-enoate hydrolase activity
hydrolase activity
hydrolase activity
acting on acid carbon-carbon bonds
in ketonic substances

1q5xA

[pdb]

1.9424
0.00544679

26^PHE 33^GLY 56^GLY 87^TRP 89^GLY 106^ASP

regulation of RNA metabolic process

ribonuclease inhibitor activity

2pz1A

[pdb]

1.9426
0.00544682

234^GLY 239^GLY 241^GLY 242^TRP 521^PHE 539^ASP

0.0.0.0

cellular_component
cytoplasm
cell projection
membrane
plasma membrane
intracellular

intracellular signaling cascade
regulation of Rho protein signal transduction

protein domain specific binding
Rho guanyl-nucleotide exchange factor activity
guanyl-nucleotide exchange factor activity
protein binding

1qutA

[pdb]

1.94896
0.00561495

166^GLY 199^PHE 208^ASP 215^GLY 222^GLY 247^TRP

cell outer membrane
membrane
plasma membrane

cell wall organization

lyase activity
carbon-oxygen lyase activity
acting on polysaccharides

1xkvA

[pdb]

1.94952
0.00561505

351^GLY 430^GLY 431^GLY 467^PHE 489^TRP 496^ASP

4.1.1.49

calcium ion binding
metal ion binding
carboxy-lyase activity
lyase activity
ATP binding
nucleotide binding
phosphoenolpyruvate carboxykinase (ATP) activity
purine nucleotide binding
phosphoenolpyruvate carboxykinase activity

cytoplasm

gluconeogenesis

2g6wA

[pdb]

1.95015
0.00561516

105^PHE 204^ASP 210^GLY 213^GLY 218^GLY 221^TRP

2.3.1.47

biotin biosynthetic process
biosynthetic process
metabolic process

transferase activity
8-amino-7-oxononanoate synthase activity
pyridoxal phosphate binding
transferase activity
transferring nitrogenous groups
catalytic activity

1tz9B

[pdb]

1.95224
0.00578482

3^TRP 4^GLY 28^GLY 63^GLY 244^PHE 317^ASP

4.2.1.8

glucuronate catabolic process

lyase activity
mannonate dehydratase activity

1sg3B

[pdb]

1.95252
0.00578487

216^GLY 234^TRP 265^ASP 276^PHE 333^GLY 334^GLY

3.5.3.4

hydrolase activity
allantoicase activity
protein binding

purine base metabolic process
allantoin catabolic process

1cx8D

[pdb]

1.95679
0.00578562

184^ASP 306^GLY 316^PHE 453^TRP 456^GLY 462^GLY

cellular iron ion homeostasis
endocytosis
interspecies interaction between organisms

membrane
extracellular region
melanosome
plasma membrane
integral to membrane
integral to plasma membrane
endosome
cytoplasmic membrane-bounded vesicle
perinuclear region of cytoplasm

transferrin receptor activity
receptor activity

1a0cA

[pdb]

1.95916
0.00595988

187^TRP 188^GLY 189^GLY 192^GLY 245^ASP 252^PHE

5.3.1.5

D-xylose metabolic process
pentose-phosphate shunt
carbohydrate metabolic process

cobalt ion binding
metal ion binding
isomerase activity
xylose isomerase activity
magnesium ion binding

cytoplasm

1pq7A

[pdb]

1.96078
0.00596017

26^ASP 29^PHE 137^GLY 138^TRP 139^GLY 197^GLY

3.4.21.4

extracellular region

hydrolase activity
serine-type peptidase activity
peptidase activity
serine-type endopeptidase activity
catalytic activity

proteolysis

1xvyA

[pdb]

1.96187
0.00596037

95^TRP 97^GLY 224^PHE 229^GLY 231^GLY 290^ASP

iron ion transport
ion transport
transport

metal ion binding
iron ion binding
transporter activity

periplasmic space

2iouD

[pdb]

1.96221
0.00596043

214^VAL 304^ASP 342^ILE 343^GLU 345^GLY 364^ALA

0.0.0.0

cell outer membrane
membrane
plasma membrane
outer membrane

pathogenesis
cell adhesion

protein binding

1fwiC

[pdb]

1.96716
0.00613987

137^TRP 158^GLY 160^GLY 164^GLY 271^PHE 360^ASP

3.5.1.5

cytoplasm
cytoplasm
cytoplasm

metal ion binding
hydrolase activity
nickel ion binding
urease activity
hydrolase activity
acting on carbon-nitrogen (but not peptide) bonds
hydrolase activity
urease activity
nickel ion binding
hydrolase activity
urease activity
nickel ion binding

urea metabolic process
nitrogen compound metabolic process
nitrogen compound metabolic process
urea metabolic process
nitrogen compound metabolic process

1q3xA

[pdb]

1.96816
0.00614006

572^GLY 573^TRP 574^GLY 589^ASP 634^GLY 648^PHE

3.4.21.104

extracellular region

innate immune response
complement activation
classical pathway
immune response
complement activation
lectin pathway
complement activation
proteolysis

protein binding
calcium-dependent protein binding
metal ion binding
hydrolase activity
serine-type peptidase activity
peptidase activity
calcium ion binding
serine-type endopeptidase activity
catalytic activity

1zatA

[pdb]

1.9714
0.00614065

348^ASP 371^GLY 382^PHE 434^TRP 438^GLY 441^GLY

0.0.0.0

2z37B

[pdb]

1.97545
0.00632482

206^PHE 216^GLY 217^TRP 219^GLY 223^GLY 360^ASP

0.0.0.0

cell wall macromolecule catabolic process
chitin catabolic process

chitin binding
chitinase activity