The LabelHash Server

Top 100 matches

For each match you can click on the "[pdb]" link to download a PDB file with the matching chain aligned with the motif.
Download a zip file with PDB files for all the matches and the motif itself.

PDB ID	LRMSD / p-value	Matching Residues	EC	Gene Ontology annotations
1czfA	[pdb]	0 2.47974e-05	178^ASN 180^ASP 201^ASP 256^ARG 258^LYS 291^TYR	3.2.1.15	extracellular region	hydrolase activity acting on glycosyl bonds hydrolase activity polygalacturonase activity	metabolic process cell wall organization carbohydrate metabolic process
2iq7C	[pdb]	0.255393 0.000100461	176^ASN 178^ASP 199^ASP 254^ARG 256^LYS 289^TYR	0.0.0.0		hydrolase activity acting on glycosyl bonds hydrolase activity polygalacturonase activity	metabolic process cell wall organization carbohydrate metabolic process
1nhcF	[pdb]	0.273977 0.000106636	184^ASN 186^ASP 207^ASP 262^ARG 264^LYS 297^TYR	3.2.1.15	extracellular region	hydrolase activity acting on glycosyl bonds hydrolase activity polygalacturonase activity	metabolic process cell wall organization carbohydrate metabolic process
1hg8A	[pdb]	0.488638 0.00019915	189^ASN 191^ASP 212^ASP 267^ARG 269^LYS 302^TYR	3.2.1.15	extracellular region	hydrolase activity acting on glycosyl bonds hydrolase activity polygalacturonase activity	metabolic process cell wall organization carbohydrate metabolic process
1ib4B	[pdb]	0.538464 0.000219561	157^ASN 159^ASP 180^ASP 235^ARG 237^LYS 270^TYR	3.2.1.15	extracellular region	hydrolase activity acting on glycosyl bonds hydrolase activity polygalacturonase activity	metabolic process cell wall organization carbohydrate metabolic process
1kcdA	[pdb]	0.681293 0.000278992	151^ASN 153^ASP 173^ASP 226^ARG 228^LYS 262^TYR	0.0.0.0		hydrolase activity acting on glycosyl bonds hydrolase activity polygalacturonase activity	metabolic process cell wall organization carbohydrate metabolic process
1bheA	[pdb]	1.02332 0.000342173	200^ASN 202^ASP 223^ASP 280^ARG 282^LYS 314^TYR	3.2.1.15	extracellular region	hydrolase activity hydrolase activity acting on glycosyl bonds polygalacturonase activity	metabolic process cell wall organization carbohydrate metabolic process
1xbfB	[pdb]	1.37068 0.000425148	7^TYR 13^ASN 14^ASP 15^ASP 44^HIS 126^LYS	0.0.0.0
1vmhA	[pdb]	1.4371 0.000471687	7^TYR 13^ASN 14^ASP 15^ASP 44^HIS 126^LYS	0.0.0.0
2uvfB	[pdb]	1.49938 0.000553498	379^ASN 381^ASP 402^ASP 466^ARG 468^LYS 501^TYR	0.0.0.0		carbohydrate metabolic process	polygalacturonase activity
1d5rA	[pdb]	1.5322 0.000602257	49^ASN 51^ASP 52^ASP 61^HIS 66^LYS 68^TYR	3.1.3.48, 3.1.3.67, 3.1.3.16	apoptosis endothelial cell migration neuron projection development angiogenesis regulation of cyclin-dependent protein kinase activity negative regulation of cell cycle cell cycle negative regulation of protein kinase B signaling cascade negative regulation of focal adhesion formation phosphoinositide dephosphorylation inositol phosphate dephosphorylation regulation of protein stability negative regulation of cell migration negative regulation of cell proliferation protein amino acid dephosphorylation cardiac muscle tissue development platelet-derived growth factor receptor signaling pathway negative regulation of apoptosis cell migration central nervous system development induction of apoptosis heart development cell proliferation lipid metabolic process	cytosol nucleus cytoplasm	protein tyrosine/serine/threonine phosphatase activity phosphatidylinositol-3-phosphatase activity protein serine/threonine phosphatase activity phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity PDZ domain binding magnesium ion binding protein binding platelet-derived growth factor receptor binding inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity protein tyrosine phosphatase activity hydrolase activity lipid binding phosphoprotein phosphatase activity
2gafD	[pdb]	1.56436 0.000662204	233^LYS 240^TYR 245^ASP 248^ASP 249^ASN 467^HIS	2.7.7.19		mRNA processing mRNA capping transcription regulation of mRNA 3'-end processing viral transcription mRNA processing transcription	transferase activity methyltransferase activity mRNA (nucleoside-2'-O-)-methyltransferase activity transferase activity polynucleotide adenylyltransferase activity nucleotide binding ATP binding
4ptdA	[pdb]	1.58164 0.000714317	116^LYS 118^TYR 163^ARG 180^ASP 181^ASN 198^ASP	4.6.1.13	extracellular region	lipid catabolic process intracellular signaling cascade lipid metabolic process	lyase activity phosphatidylinositol diacylglycerol-lyase activity phosphoric diester hydrolase activity phospholipase C activity
1kaeB	[pdb]	1.63244 0.000866667	38^ASP 41^ASP 42^ASN 130^TYR 218^LYS 219^ARG	1.1.1.23		metal ion binding oxidoreductase activity zinc ion binding histidinol dehydrogenase activity NAD or NADH binding	oxidation reduction cellular amino acid biosynthetic process histidine biosynthetic process metabolic process
1ouuD	[pdb]	1.64029 0.000892241	85^TYR 86^LYS 99^ASP 101^ASP 102^ASN 144^ARG		hemoglobin complex hemoglobin complex	metal ion binding iron ion binding oxygen transporter activity heme binding oxygen binding metal ion binding iron ion binding oxygen transporter activity heme binding oxygen binding	oxygen transport transport oxygen transport transport
1nikA	[pdb]	1.65073 0.000918491	368^GLU 399^ASP 438^ASP 439^ASN 440^ASP 465^ASN	2.7.7.6	DNA-directed RNA polymerase III complex nucleus DNA-directed RNA polymerase I complex DNA-directed RNA polymerase III complex DNA-directed RNA polymerase II core complex nucleoplasm nucleus mitochondrion DNA-directed RNA polymerase II core complex nucleolus nucleolus nucleus DNA-directed RNA polymerase I complex DNA-directed RNA polymerase II core complex nucleoplasm nucleus DNA-directed RNA polymerase II core complex nucleoplasm nucleus DNA-directed RNA polymerase II core complex nucleus DNA-directed RNA polymerase I complex DNA-directed RNA polymerase III complex DNA-directed RNA polymerase II core complex nucleoplasm cytoplasm nucleus DNA-directed RNA polymerase I complex DNA-directed RNA polymerase III complex DNA-directed RNA polymerase II core complex nucleoplasm RNA polymerase complex nucleus mitochondrion DNA-directed RNA polymerase II core complex nucleus DNA-directed RNA polymerase II core complex nucleus DNA-directed RNA polymerase I complex DNA-directed RNA polymerase III complex DNA-directed RNA polymerase II core complex nucleoplasm	ribonucleoside binding metal ion binding zinc ion binding DNA-directed RNA polymerase activity DNA binding metal ion binding nucleotidyltransferase activity transferase activity zinc ion binding DNA-directed RNA polymerase activity DNA binding magnesium ion binding protein binding protein binding protein binding protein binding protein binding metal ion binding zinc ion binding DNA-directed RNA polymerase activity DNA binding protein binding metal ion binding zinc ion binding DNA-directed RNA polymerase activity protein dimerization activity DNA binding metal ion binding zinc ion binding DNA-directed RNA polymerase activity transcription regulator activity DNA binding nucleic acid binding protein binding DNA-directed RNA polymerase activity DNA binding protein binding DNA-directed RNA polymerase activity DNA binding metal ion binding nucleotidyltransferase activity transferase activity zinc ion binding DNA-directed RNA polymerase activity magnesium ion binding DNA binding DNA-directed RNA polymerase activity protein dimerization activity DNA binding DNA-directed RNA polymerase activity protein binding	transcription from RNA polymerase II promoter transcription transcription transcription from RNA polymerase II promoter RNA elongation from RNA polymerase II promoter transcription transcription from RNA polymerase II promoter regulation of transcription transcription transcription from RNA polymerase II promoter response to DNA damage stimulus transcription DNA repair response to drug transcription from RNA polymerase II promoter transcription-coupled nucleotide-excision repair regulation of transcription transcription transcription from RNA polymerase II promoter transcription transcription from RNA polymerase II promoter transcription DNA-dependent transcription transcription from RNA polymerase II promoter transcription transcription from RNA polymerase II promoter transcription transcription from RNA polymerase II promoter
2oxaA	[pdb]	1.66093 0.000945963	79^ASP 145^ASN 148^ASP 179^ARG 212^TYR 214^LYS	0.0.0.0		peptidase activity serine-type endopeptidase activity serine-type peptidase activity hydrolase activity	proteolysis
1cm8A	[pdb]	1.66693 0.000974586	135^TYR 139^LYS 142^ARG 153^ASP 158^ASN 171^ASP	2.7.11.24	cell cycle arrest myoblast differentiation cell cycle Ras protein signal transduction intracellular signaling cascade muscle organ development signal transduction DNA damage induced protein phosphorylation protein amino acid phosphorylation	magnesium ion binding protein binding protein serine/threonine kinase activity metal ion binding transferase activity kinase activity ATP binding nucleotide binding MAP kinase activity protein kinase activity	mitochondrion cytoplasm
2j63B	[pdb]	1.69786 0.00110293	169^LYS 200^TYR 204^ARG 335^ASP 337^ASN 411^ASP	0.0.0.0	DNA repair	intracellular	lyase activity endonuclease activity DNA-(apurinic or apyrimidinic site) lyase activity nuclease activity DNA binding
1lp4A	[pdb]	1.7247 0.0012527	138^TYR 142^LYS 148^HIS 156^ASP 161^ASN 175^ASP	2.7.11.1		protein amino acid phosphorylation	transferase activity kinase activity ATP binding protein serine/threonine kinase activity nucleotide binding protein kinase activity
2dgaA	[pdb]	1.72535 0.00125273	266^TYR 340^LYS 341^HIS 353^ASN 355^ASP 356^ASP	0.0.0.0		hydrolase activity acting on glycosyl bonds hydrolase activity beta-glucosidase activity cation binding hydrolase activity hydrolyzing O-glycosyl compounds catalytic activity	metabolic process carbohydrate metabolic process
1bxcD	[pdb]	1.72624 0.00125276	2^TYR 5^LYS 48^HIS 244^ASP 246^ASN 286^ASP	5.3.1.5	D-xylose metabolic process pentose-phosphate shunt carbohydrate metabolic process	cytoplasm	metal ion binding isomerase activity magnesium ion binding xylose isomerase activity
1q7fB	[pdb]	1.7286 0.00125286	766^TYR 769^LYS 792^ASN 793^ASP 808^ASP 1023^ARG		cytoplasm intracellular basal cortex apical cortex	protein binding translation repressor activity metal ion binding zinc ion binding translation regulator activity	rRNA transcription regulation of translation oogenesis segmentation asymmetric cell division negative regulation of cell proliferation brain development negative regulation of neuroblast proliferation neuroblast proliferation ganglion mother cell fate determination phagocytosis engulfment
2zo9C	[pdb]	1.72947 0.00129308	12^ARG 17^LYS 19^TYR 50^ASP 80^ASN 82^ASP	0.0.0.0			hydrolase activity
2rkpA	[pdb]	1.73102 0.00129315	138^TYR 142^LYS 148^HIS 156^ASP 161^ASN 175^ASP	2.7.11.1	Wnt receptor signaling pathway signal transduction protein amino acid phosphorylation	plasma membrane nucleus	protein serine/threonine kinase activity protein N-terminus binding transferase activity kinase activity ATP binding nucleotide binding protein kinase activity protein binding
1hgxA	[pdb]	1.76681 0.00152195	16^ASN 18^ASP 19^ASP 25^ARG 53^TYR 58^LYS		cytoplasm	metal ion binding transferase activity transferring glycosyl groups transferase activity magnesium ion binding hypoxanthine phosphoribosyltransferase activity	purine ribonucleoside salvage nucleoside metabolic process
2icrA	[pdb]	1.76793 0.00152201	6^HIS 10^ASP 11^ASP 36^ASN 82^TYR 84^LYS	0.0.0.0			protein-chromophore linkage bioluminescence
1z57A	[pdb]	1.77836 0.00157355	270^TYR 274^LYS 280^HIS 288^ASP 293^ASN 325^ASP	2.7.12.1	cell proliferation protein amino acid phosphorylation	nucleus	transferase activity kinase activity ATP binding protein tyrosine kinase activity protein serine/threonine kinase activity nucleotide binding non-membrane spanning protein tyrosine kinase activity protein kinase activity
2e6kB	[pdb]	1.78059 0.00157367	52^ASN 55^ASP 57^ASP 76^TYR 100^LYS 109^HIS	0.0.0.0		metabolic process	transferase activity transketolase activity catalytic activity
1bbjH	[pdb]	1.80693 0.00179209	35^HIS 55^ASN 56^ASP 57^ASP 97^LYS 101^TYR		antigen binding	immune response	membrane fraction extracellular region
3f8uC	[pdb]	1.81909 0.00185194	250^LEU 251^ALA 253^ILE 265^GLU 305^GLY 309^GLU	5.3.4.1	microsome Golgi membrane endoplasmic reticulum membrane MHC class I peptide loading complex integral to membrane membrane endoplasmic reticulum endoplasmic reticulum melanosome endoplasmic reticulum lumen	protein binding MHC class I protein binding TAP2 binding TAP1 binding peptide antigen binding unfolded protein binding peptide antigen-transporting ATPase activity isomerase activity protein disulfide isomerase activity phospholipase C activity cysteine-type endopeptidase activity protein binding	retrograde vesicle-mediated transport Golgi to ER peptide antigen stabilization immune response protein complex assembly antigen processing and presentation of endogenous peptide antigen via MHC class I signal transduction protein retention in ER lumen protein import into nucleus cell redox homeostasis positive regulation of apoptosis
1pvwB	[pdb]	1.82668 0.00197702	20^TYR 189^ASP 190^ASP 192^ASN 200^LYS 201^ARG	4.1.99.12		metal ion binding manganese ion binding lyase activity magnesium ion binding 3,4-dihydroxy-2-butanone-4-phosphate synthase activity	riboflavin biosynthetic process
1olpA	[pdb]	1.83256 0.00197741	67^ASP 77^ASN 92^ASP 99^ARG 190^LYS 195^TYR	0.0.0.0			phospholipase C activity hydrolase activity acting on ester bonds zinc ion binding
3ebyA	[pdb]	1.8325 0.00197741	16^ASP 17^ASP 19^ASN 44^TYR 132^ARG 143^LYS	0.0.0.0		cellular aromatic compound metabolic process oxidation reduction	oxidoreductase activity acting on single donors with incorporation of molecular oxygen incorporation of two atoms of oxygen catalytic activity
3e3bX	[pdb]	1.83749 0.00204332	139^TYR 143^LYS 149^HIS 157^ASP 162^ASN 176^ASP	2.7.11.1		Wnt receptor signaling pathway protein amino acid phosphorylation regulation of cell cycle	protein N-terminus binding transferase activity kinase activity ATP binding protein serine/threonine kinase activity nucleotide binding protein kinase activity protein binding
2a1aB	[pdb]	1.84489 0.00211166	300^TYR 304^LYS 307^ARG 414^ASP 419^ASN 432^ASP	2.7.11.1	interspecies interaction between organisms response to virus negative regulation of cell proliferation protein amino acid phosphorylation protein amino acid autophosphorylation endoplasmic reticulum unfolded protein response translation translation translational initiation virus-infected cell apoptosis	intracellular ribosome cytoplasm multi-eIF complex eukaryotic translation initiation factor 2 complex	transferase activity kinase activity ATP binding protein serine/threonine kinase activity RNA binding nucleotide binding protein phosphatase type 2A regulator activity eukaryotic translation initiation factor 2alpha kinase activity protein kinase activity protein binding translation initiation factor activity RNA binding double-stranded RNA binding
2qg7E	[pdb]	1.84789 0.00211187	207^LYS 210^HIS 296^ASP 363^ASP 366^ASN 394^TYR	0.0.0.0			kinase activity
3fi8A	[pdb]	1.85017 0.00218216	211^LYS 213^HIS 288^ASP 317^ASP 320^ASN 357^TYR	0.0.0.0			kinase activity
1dghD	[pdb]	1.85669 0.00225393	144^ASP 218^HIS 231^TYR 233^LYS 335^ASP 338^ASN	1.11.1.6	heme binding catalase activity protein homodimerization activity NADP or NADPH binding oxidoreductase activity acting on peroxide as acceptor metal ion binding oxidoreductase activity growth factor activity iron ion binding peroxidase activity aminoacylase activity	hydrogen peroxide catabolic process UV protection protein tetramerization negative regulation of apoptosis response to reactive oxygen species oxidation reduction cell proliferation response to oxidative stress positive regulation of NF-kappaB transcription factor activity negative regulation of NF-kappaB transcription factor activity hemoglobin metabolic process positive regulation of phosphoinositide 3-kinase cascade aerobic respiration cholesterol metabolic process triglyceride metabolic process	peroxisome peroxisomal membrane mitochondrion
1th4D	[pdb]	1.85667 0.00225393	143^ASP 217^HIS 230^TYR 232^LYS 334^ASP 337^ASN	1.11.1.6	metal ion binding oxidoreductase activity growth factor activity iron ion binding peroxidase activity catalase activity heme binding aminoacylase activity oxidoreductase activity acting on peroxide as acceptor	oxidation reduction hydrogen peroxide catabolic process cell proliferation response to oxidative stress triglyceride metabolic process cholesterol metabolic process aerobic respiration positive regulation of phosphoinositide 3-kinase cascade hemoglobin metabolic process negative regulation of NF-kappaB transcription factor activity positive regulation of NF-kappaB transcription factor activity	peroxisome mitochondrion peroxisomal membrane
2qkwB	[pdb]	1.87169 0.00240246	54^LYS 56^TYR 71^ARG 164^ASP 169^ASN 182^ASP	0.0.0.0		nucleotide binding kinase activity protein serine/threonine kinase activity ATP binding protein kinase activity	protein amino acid phosphorylation
3c5iA	[pdb]	1.87447 0.00240268	141^LYS 143^HIS 218^ASP 247^ASP 250^ASN 287^TYR	0.0.0.0			kinase activity
1e5mA	[pdb]	1.87904 0.00240304	227^ASP 320^ARG 323^LYS 331^TYR 374^ASN 376^ASP	2.3.1.179		lipid biosynthetic process fatty acid biosynthetic process biosynthetic process metabolic process	transferase activity acyltransferase activity beta-ketoacyl-acyl-carrier-protein synthase II activity transferase activity transferring acyl groups other than amino-acyl groups catalytic activity
1x56A	[pdb]	1.88565 0.00248097	337^ASP 339^ASN 340^ASP 368^TYR 370^LYS 374^ARG	6.1.1.22	cytoplasm	ligase activity ATP binding aminoacyl-tRNA ligase activity nucleotide binding asparagine-tRNA ligase activity aspartate-tRNA ligase activity nucleic acid binding	translation aspartyl-tRNA aminoacylation asparaginyl-tRNA aminoacylation tRNA aminoacylation for protein translation
1zrzA	[pdb]	1.88883 0.00256118	253^ARG 256^TYR 258^LYS 330^ASP 373^ASP 374^ASN	2.7.11.13	cytosol polarisome nucleus membrane endosome cytoplasm apical part of cell apical plasma membrane	membrane organization cytoskeleton organization vesicle-mediated transport establishment or maintenance of epithelial cell apical/basal polarity protein targeting to membrane secretion cell-cell junction organization signal transduction protein amino acid phosphorylation intracellular signaling cascade eye photoreceptor cell development establishment of apical/basal cell polarity actin filament organization Golgi vesicle budding cellular response to insulin stimulus positive regulation of glucose import regulation of establishment of protein localization	protein binding phospholipid binding ATP binding transferase activity kinase activity zinc ion binding protein serine/threonine kinase activity nucleotide binding metal ion binding diacylglycerol binding protein kinase C activity protein kinase activity
1qnzH	[pdb]	1.89074 0.00256134	152^ASN 172^TYR 179^LYS 197^ARG 201^ASP 202^ASP			antigen binding antigen binding	viral envelope
3e93A	[pdb]	1.89625 0.00264438	132^TYR 139^LYS 142^HIS 150^ASP 155^ASN 168^ASP	2.7.11.24	MP kinase activity transferase activity kinase activity ATP binding protein serine/threonine kinase activity nucleotide binding MAP kinase activity MAP kinase kinase activity protein kinase activity protein binding	cytoplasm nucleus cytosol nucleoplasm spindle pole cell	response to stress protein kinase cascade Ras protein signal transduction intracellular signaling cascade chemotaxis cell surface receptor linked signal transduction signal transduction cell motion protein amino acid phosphorylation DNA damage checkpoint angiogenesis chondrocyte differentiation glucose metabolic process skeletal muscle tissue development fatty acid oxidation lipopolysaccharide-mediated signaling pathway response to muramyl dipeptide response to lipopolysaccharide positive regulation of erythrocyte differentiation positive regulation of transcription from RNA polymerase II promoter
2ixbA	[pdb]	1.89785 0.00264452	150^ASN 355^TYR 361^LYS 363^HIS 376^ASP 380^ASP			hydrolase activity acting on glycosyl bonds hydrolase activity alpha-N-acetylgalactosaminidase activity oxidoreductase activity binding catalytic activity	metabolic process
2odjB	[pdb]	1.8979 0.00264452	271^TYR 273^LYS 275^HIS 364^ASP 398^ASN 400^ASP		basic amino acid transport ion transport transport	integral to cell outer membrane cell outer membrane integral to membrane membrane plasma membrane	porin activity serine-type peptidase activity hydrolase activity peptidase activity
2eklA	[pdb]	1.90018 0.00264472	47^TYR 70^LYS 80^ASP 81^ASN 83^ASP 90^ARG	0.0.0.0		NAD or NADH binding cofactor binding oxidoreductase activity acting on the CH-OH group of donors NAD or NADP as acceptor binding phosphoglycerate dehydrogenase activity catalytic activity	metabolic process L-serine biosynthetic process oxidation reduction
2oqhD	[pdb]	1.90185 0.00273016	91^TYR 197^ASP 199^ASN 224^ASP 273^LYS 297^HIS	0.0.0.0		isomerase activity catalytic activity	metabolic process
1i2dB	[pdb]	1.90522 0.00273046	200^ASN 234^ASP 236^ASP 378^TYR 383^LYS 386^ARG	2.7.7.4	cysteine biosynthetic process methionine biosynthetic process cellular amino acid biosynthetic process sulfate assimilation	cytoplasm	nucleotidyltransferase activity transferase activity ATP binding catalytic activity nucleotide binding sulfate adenylyltransferase (ATP) activity transferase activity transferring phosphorus-containing groups kinase activity
1lf9A	[pdb]	1.91264 0.00281925	182^LYS 187^TYR 227^ARG 331^ASP 332^ASP 333^ASN	0.0.0.0		hydrolase activity acting on glycosyl bonds hydrolase activity glucan 1,4-alpha-glucosidase activity carbohydrate binding catalytic activity	metabolic process polysaccharide metabolic process carbohydrate metabolic process
2erkA	[pdb]	1.91513 0.00281947	129^TYR 136^LYS 139^HIS 147^ASP 152^ASN 165^ASP	2.7.11.24	nucleoplasm protein complex perikaryon axon part dendrite cytoplasm cytosol nucleus insoluble fraction soluble fraction	sensory perception of pain cell cycle positive regulation of transcription positive regulation of translation response to estrogen stimulus response to chemical stimulus positive regulation of cell migration positive regulation of cell proliferation protein kinase cascade intracellular signaling cascade signal transduction protein amino acid phosphorylation nuclear translocation of MAPK MAPKKK cascade	transferase activity kinase activity ATP binding protein serine/threonine kinase activity nucleotide binding MAP kinase activity mitogen-activated protein kinase kinase kinase binding protein binding protein kinase activity
2r7oA	[pdb]	1.92228 0.0029112	242^LYS 326^TYR 457^ARG 520^ASP 631^ASP 633^ASN	2.7.7.48	RNA-directed RNA polymerase activity RNA binding nucleotide binding magnesium ion binding transferase activity nucleotidyltransferase activity	viral genome replication transcription transcription RNA-dependent	virion viral nucleocapsid
2v62B	[pdb]	1.92613 0.00300413	22^ASP 23^ASP 27^ASN 44^TYR 61^LYS 117^ARG	2.7.11.1	membrane integral to membrane membrane fraction endoplasmic reticulum	protein amino acid phosphorylation protein amino acid autophosphorylation	transferase activity kinase activity ATP binding protein serine/threonine kinase activity nucleotide binding protein kinase activity protein binding
1ftaC	[pdb]	1.93161 0.0030988	209^TYR 218^ASP 220^ASP 229^ARG 230^LYS 267^ASN	3.1.3.11	gluconeogenesis carbohydrate metabolic process fructose metabolic process	hydrolase activity zinc ion binding catalytic activity fructose 1,6-bisphosphate 1-phosphatase activity fructose-2,6-bisphosphate 2-phosphatase activity phosphoric ester hydrolase activity identical protein binding protein binding magnesium ion binding metal ion binding	mitochondrion cytosol
2i6lB	[pdb]	1.93598 0.00309923	134^TYR 141^LYS 144^HIS 152^ASP 157^ASN 171^ASP	2.7.11.24	cell cycle signal transduction protein amino acid phosphorylation	cytoplasm	transferase activity kinase activity ATP binding protein serine/threonine kinase activity nucleotide binding MAP kinase activity protein kinase activity protein binding
1eq2C	[pdb]	1.93636 0.00309927	31^ASP 32^ASN 52^ASP 74^HIS 94^TYR 98^LYS	5.1.3.20	isomerase activity ADP-glyceromanno-heptose 6-epimerase activity coenzyme binding NADP or NADPH binding binding catalytic activity protein binding	lipopolysaccharide biosynthetic process response to stress carbohydrate metabolic process cellular metabolic process metabolic process	membrane cytosol mitochondrion
1nw1B	[pdb]	1.9409 0.00319707	179^LYS 181^HIS 255^ASP 313^ASP 316^ASN 353^TYR	0.0.0.0			kinase activity
1n8vB	[pdb]	1.94368 0.00319735	6^ASP 9^ASP 10^ASN 26^TYR 44^LYS 46^HIS	0.0.0.0
1gq2I	[pdb]	1.95752 0.0034037	31^ASP 90^ASP 92^ASN 194^LYS 196^HIS 558^TYR	1.1.1.40	cytoplasm	metal ion binding oxidoreductase activity malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) activity NAD or NADH binding oxidoreductase activity acting on the CH-OH group of donors NAD or NADP as acceptor binding malic enzyme activity catalytic activity	oxidation reduction metabolic process malate metabolic process
2duoB	[pdb]	1.95942 0.00340391	87^TYR 119^LYS 207^ARG 229^ASP 232^ASP 234^ASN		Golgi membrane integral to membrane membrane Golgi apparatus	protein transport transport	sugar binding calcium ion binding
2r91A	[pdb]	1.96187 0.00351206	128^ARG 132^LYS 133^TYR 149^ASN 157^ASP 159^ASP	0.0.0.0		lyase activity catalytic activity	metabolic process
2no4B	[pdb]	1.96243 0.00351213	11^ASP 58^TYR 149^LYS 156^ARG 178^ASN 181^ASP	3.8.1.2		hydrolase activity (S)-2-haloacid dehalogenase activity hydrolase activity acting on acid halide bonds in C-halide compounds phosphoglycolate phosphatase activity catalytic activity	metabolic process
2w1gA	[pdb]	1.97217 0.003625	246^TYR 250^LYS 256^ASP 261^ASN 274^ASP 280^HIS	2.7.11.1	protein binding transferase activity kinase activity ATP binding protein serine/threonine kinase activity nucleotide binding protein kinase activity ubiquitin protein ligase binding	regulation of protein stability cell cycle spindle organization phosphoinositide-mediated signaling mitosis protein amino acid phosphorylation mitotic cell cycle	spindle centrosome nucleus
2zs1B	[pdb]	1.98399 0.0038624	11^VAL 12^ILE 18^VAL 125^ALA 126^HIS 127^ILE		extracellular region hemoglobin complex extracellular region hemoglobin complex extracellular region hemoglobin complex extracellular region hemoglobin complex	metal ion binding iron ion binding oxygen transporter activity heme binding oxygen binding metal ion binding iron ion binding oxygen transporter activity heme binding oxygen binding metal ion binding iron ion binding oxygen transporter activity heme binding oxygen binding metal ion binding iron ion binding oxygen transporter activity heme binding oxygen binding	oxygen transport transport oxygen transport transport oxygen transport transport oxygen transport transport
2fgtA	[pdb]	1.987 0.00386278	71^HIS 80^ASP 81^ASP 82^ASN 125^LYS 172^TYR			metal ion binding calcium ion binding	plasma membrane integral to membrane membrane
3coiA	[pdb]	1.99428 0.00398837	132^TYR 136^LYS 142^HIS 150^ASP 155^ASN 168^ASP	2.7.11.24		MP kinase activity transferase activity kinase activity ATP binding protein serine/threonine kinase activity nucleotide binding MAP kinase activity protein binding protein kinase activity	protein kinase cascade response to stress cell cycle Ras protein signal transduction intracellular signaling cascade protein amino acid phosphorylation
1ffyA	[pdb]	1.99832 0.00398888	680^TYR 797^LYS 799^ARG 806^ASP 807^ASP 809^ASN	6.1.1.5	cytoplasm	metal ion binding ligase activity zinc ion binding ATP binding aminoacyl-tRNA ligase activity nucleotide binding isoleucine-tRNA ligase activity catalytic activity	translation isoleucyl-tRNA aminoacylation tRNA aminoacylation for protein translation
2zr2B	[pdb]	1.99825 0.00398887	119^ASP 122^ASP 123^ASN 141^ARG 338^TYR 367^LYS	6.1.1.11	cytoplasm	ligase activity ATP binding aminoacyl-tRNA ligase activity nucleotide binding serine-tRNA ligase activity	translation seryl-tRNA aminoacylation tRNA aminoacylation for protein translation selenocysteine biosynthetic process
1ixkA	[pdb]	2.0043 0.00411667	244^TYR 263^ASP 264^ASN 266^ASP 311^LYS 313^ARG	0.0.0.0		S-adenosylmethionine-dependent methyltransferase activity RNA binding methyltransferase activity	rRNA processing
2v05A	[pdb]	2.00529 0.0041168	9^ASP 11^ASP 12^ASN 21^HIS 22^LYS 25^TYR	0.0.0.0
2d40B	[pdb]	2.00739 0.00424656	47^TYR 132^ASN 135^ASP 218^ASP 281^HIS 301^LYS	0.0.0.0			oxidoreductase activity acting on single donors with incorporation of molecular oxygen incorporation of two atoms of oxygen
1n44A	[pdb]	2.0101 0.00424693	48^ARG 62^ASP 65^ASN 66^ASP 84^LYS 89^TYR	0.0.0.0		blood coagulation negative regulation of coagulation response to organic substance protein homooligomerization	calcium-dependent phospholipid binding calcium ion binding protein binding receptor tyrosine kinase binding eukaryotic cell surface binding
1wk1A	[pdb]	2.01029 0.00424695	33^TYR 40^ASP 41^ASP 43^ASN 129^LYS 131^ARG	0.0.0.0			binding
3gfoA	[pdb]	2.01543 0.00438218	90^ASP 92^ASP 93^ASN 101^TYR 137^LYS 140^HIS	0.0.0.0	cobalt ion binding hydrolase activity cobalt ion transmembrane transporter activity ATP binding nucleotide binding nucleoside-triphosphatase activity ATPase activity	cobalt ion transport ion transport transport	plasma membrane membrane Gram-negative-bacterium-type cell wall
1jc9A	[pdb]	2.01607 0.00438227	94^ARG 98^TYR 121^LYS 147^ASP 150^ASN 151^ASP		cell-cell adhesion signal transduction	extracellular region	sugar binding calcium ion binding receptor binding metal ion binding
2eixB	[pdb]	2.01951 0.00438276	65^ARG 118^LYS 120^TYR 194^ASN 196^ASP 197^ASP	0.0.0.0		oxidation reduction	oxidoreductase activity electron carrier activity
11asB	[pdb]	2.02147 0.00452288	77^LYS 78^ARG 93^TYR 219^ASP 220^ASP 233^ASN	6.3.1.1	cellular amino acid biosynthetic process asparagine biosynthetic process tRNA aminoacylation for protein translation translation	cytoplasm	ligase activity aspartate-ammonia ligase activity ATP binding aminoacyl-tRNA ligase activity nucleotide binding protein binding
2f49A	[pdb]	2.03429 0.00467026	119^TYR 126^LYS 129^HIS 137^ASP 142^ASN 155^ASP	2.7.11.24	cell division mitosis cell cycle conjugation negative regulation of MAPKKK cascade cell cycle arrest protein amino acid phosphorylation invasive growth in response to glucose limitation pheromone-dependent signal transduction involved in conjugation with cellular fusion	periplasmic space cytoplasm nucleus mating projection tip mitochondrion	transferase activity kinase activity ATP binding protein serine/threonine kinase activity nucleotide binding MAP kinase activity protein kinase activity protein binding
1dnkA	[pdb]	2.03625 0.00482195	76^TYR 77^LYS 79^ARG 168^ASP 170^ASN 212^ASP	3.1.21.1	apoptosis DNA catabolic process	hydrolase activity calcium ion binding endonuclease activity nuclease activity actin binding deoxyribonuclease I activity deoxyribonuclease activity	nuclear envelope extracellular region nucleus
2iukA	[pdb]	2.04172 0.00482282	445^ARG 453^LYS 455^TYR 482^ASP 484^ASP 485^ASN	1.13.11.12	cytoplasm	metal ion binding oxidoreductase activity acting on single donors with incorporation of molecular oxygen incorporation of two atoms of oxygen oxidoreductase activity iron ion binding lipoxygenase activity electron carrier activity	oxidation reduction oxylipin biosynthetic process lipid biosynthetic process fatty acid biosynthetic process
3cf4A	[pdb]	2.04652 0.00498121	55^VAL 56^LYS 58^SER 678^TYR 801^LYS 802^ARG	1.2.99.2	cytoplasm	iron ion binding metal ion binding catalytic activity oxidoreductase activity carbon-monoxide dehydrogenase (acceptor) activity 4 iron 4 sulfur cluster binding iron-sulfur cluster binding nickel ion binding electron carrier activity catalytic activity	metabolic process oxidation reduction generation of precursor metabolites and energy acetyl-CoA metabolic process
2gfiB	[pdb]	2.04726 0.00498133	382^LYS 383^TYR 392^ARG 416^ASN 417^ASP 420^ASP	0.0.0.0			hydrolase activity 3-phytase activity acid phosphatase activity
2qt3B	[pdb]	2.04817 0.00498148	11^ASN 22^ASP 29^ARG 46^ASP 357^TYR 364^LYS	3.5.99.4		cytoplasm	hydrolase activity N-isopropylammelide isopropylaminohydrolase activity hydrolase activity acting on carbon-nitrogen (but not peptide) bonds
1khoA	[pdb]	2.04996 0.00498178	293^ASP 297^ASN 298^ASP 327^ARG 330^LYS 331^TYR	3.1.4.3	extracellular region	hemolysis by symbiont of host erythrocytes cytolysis pathogenesis	metal ion binding hydrolase activity zinc ion binding calcium ion binding phosphatidylcholine phospholipase C activity hydrolase activity acting on ester bonds phospholipase C activity
2fuvB	[pdb]	2.05151 0.00514618	476^ASP 481^ARG 496^LYS 500^ASP 501^ASN 518^TYR	0.0.0.0		carbohydrate metabolic process	metal ion binding isomerase activity magnesium ion binding phosphoglucomutase activity intramolecular transferase activity phosphotransferases
2eaeA	[pdb]	2.05296 0.00514643	16^ASP 17^ASP 160^ASN 357^TYR 367^LYS 368^ARG	0.0.0.0
3bkbA	[pdb]	2.05997 0.00531864	673^TYR 677^LYS 683^ASP 688^ASN 701^ASP 706^ARG	2.7.10.2	multicellular organismal development cell proliferation protein amino acid phosphorylation peptidyl-tyrosine phosphorylation	nucleus	protein binding transferase activity kinase activity ATP binding protein tyrosine kinase activity nucleotide binding non-membrane spanning protein tyrosine kinase activity protein kinase activity
2esmB	[pdb]	2.07057 0.00549505	84^ARG 105^LYS 150^TYR 160^ASP 202^ASP 203^ASN	2.7.11.1	cytosol intracellular cytoplasm Golgi membrane membrane Golgi apparatus centriole	identical protein binding nucleotide binding protein serine/threonine kinase activity protein kinase activity ATP binding protein binding metal ion binding diacylglycerol binding transferase activity kinase activity zinc ion binding	leukocyte migration Rho protein signal transduction signal transduction actin cytoskeleton organization protein amino acid phosphorylation intracellular signaling cascade cytokinesis negative regulation of neuron apoptosis bleb formation membrane to membrane docking leukocyte adhesion leukocyte tethering or rolling apoptosis
2c7hA	[pdb]	2.07116 0.00549515	11^TYR 12^LYS 64^ASP 65^ASP 66^ASN 78^ARG		metal ion binding zinc ion binding protein binding ubiquitin-protein ligase activity nucleic acid binding	nucleus ubiquitin ligase complex nucleolus	protein ubiquitination
1v4xD	[pdb]	2.07514 0.0056741	685^TYR 699^ASP 701^ASP 702^ASN 744^LYS 746^HIS	0.0.0.0	hemoglobin complex hemoglobin complex	metal ion binding iron ion binding oxygen transporter activity heme binding oxygen binding metal ion binding iron ion binding oxygen transporter activity heme binding oxygen binding	oxygen transport transport oxygen transport transport
1spgB	[pdb]	2.07959 0.00567493	85^TYR 86^LYS 99^ASP 101^ASP 102^ASN 144^ARG		hemoglobin complex hemoglobin complex	metal ion binding iron ion binding oxygen transporter activity heme binding oxygen binding metal ion binding iron ion binding oxygen transporter activity heme binding oxygen binding	oxygen transport transport oxygen transport transport
1e09A	[pdb]	2.08167 0.00586104	25^ASP 27^ASP 28^ASN 66^TYR 68^LYS 69^HIS				response to biotic stimulus defense response
2fvmC	[pdb]	2.08194 0.00586109	318^ASN 320^ASP 321^ASP 362^TYR 373^LYS 374^HIS	3.5.2.2			metal ion binding hydrolase activity zinc ion binding dihydropyrimidinase activity hydrolase activity acting on carbon-nitrogen (but not peptide) bonds
2p3yA	[pdb]	2.08875 0.00605593	369^ASP 371^ASP 373^ASN 382^LYS 384^HIS 435^TYR	0.0.0.0
2r0tB	[pdb]	2.08882 0.00605595	92^TYR 103^LYS 108^ASP 113^ASN 115^ASP 353^HIS	0.0.0.0			pyridoxal phosphate binding catalytic activity
3b95A	[pdb]	2.08988 0.00605616	813^HIS 817^LYS 839^ASP 840^ASP 852^TYR 873^ASN	2.1.1.43	histone methylation chromatin modification	histone-lysine N-methyltransferase activity methyltransferase activity metal ion binding transferase activity zinc ion binding	nucleus
3cs0A	[pdb]	2.09051 0.00605629	104^ASN 131^ASP 135^ASP 257^TYR 261^LYS 262^ARG		hydrolase activity serine-type peptidase activity peptidase activity protein binding serine-type endopeptidase activity catalytic activity	periplasmic space	response to stress proteolysis

PDB ID

LRMSD /
p-value

Matching Residues

Gene Ontology annotations

Biological Process

Cellular Component

Molecular Function

1czfA

[pdb]

0
2.47974e-05

178^ASN 180^ASP 201^ASP 256^ARG 258^LYS 291^TYR

3.2.1.15

extracellular region

hydrolase activity
acting on glycosyl bonds
hydrolase activity
polygalacturonase activity

metabolic process
cell wall organization
carbohydrate metabolic process

2iq7C

[pdb]

0.255393
0.000100461

176^ASN 178^ASP 199^ASP 254^ARG 256^LYS 289^TYR

0.0.0.0

hydrolase activity
acting on glycosyl bonds
hydrolase activity
polygalacturonase activity

metabolic process
cell wall organization
carbohydrate metabolic process

1nhcF

[pdb]

0.273977
0.000106636

184^ASN 186^ASP 207^ASP 262^ARG 264^LYS 297^TYR

3.2.1.15

extracellular region

hydrolase activity
acting on glycosyl bonds
hydrolase activity
polygalacturonase activity

metabolic process
cell wall organization
carbohydrate metabolic process

1hg8A

[pdb]

0.488638
0.00019915

189^ASN 191^ASP 212^ASP 267^ARG 269^LYS 302^TYR

3.2.1.15

extracellular region

hydrolase activity
acting on glycosyl bonds
hydrolase activity
polygalacturonase activity

metabolic process
cell wall organization
carbohydrate metabolic process

1ib4B

[pdb]

0.538464
0.000219561

157^ASN 159^ASP 180^ASP 235^ARG 237^LYS 270^TYR

3.2.1.15

extracellular region

hydrolase activity
acting on glycosyl bonds
hydrolase activity
polygalacturonase activity

metabolic process
cell wall organization
carbohydrate metabolic process

1kcdA

[pdb]

0.681293
0.000278992

151^ASN 153^ASP 173^ASP 226^ARG 228^LYS 262^TYR

0.0.0.0

hydrolase activity
acting on glycosyl bonds
hydrolase activity
polygalacturonase activity

metabolic process
cell wall organization
carbohydrate metabolic process

1bheA

[pdb]

1.02332
0.000342173

200^ASN 202^ASP 223^ASP 280^ARG 282^LYS 314^TYR

3.2.1.15

extracellular region

hydrolase activity
hydrolase activity
acting on glycosyl bonds
polygalacturonase activity

metabolic process
cell wall organization
carbohydrate metabolic process

1xbfB

[pdb]

1.37068
0.000425148

7^TYR 13^ASN 14^ASP 15^ASP 44^HIS 126^LYS

0.0.0.0

1vmhA

[pdb]

1.4371
0.000471687

7^TYR 13^ASN 14^ASP 15^ASP 44^HIS 126^LYS

0.0.0.0

2uvfB

[pdb]

1.49938
0.000553498

379^ASN 381^ASP 402^ASP 466^ARG 468^LYS 501^TYR

0.0.0.0

carbohydrate metabolic process

polygalacturonase activity

1d5rA

[pdb]

1.5322
0.000602257

49^ASN 51^ASP 52^ASP 61^HIS 66^LYS 68^TYR

3.1.3.48, 3.1.3.67, 3.1.3.16

apoptosis
endothelial cell migration
neuron projection development
angiogenesis
regulation of cyclin-dependent protein kinase activity
negative regulation of cell cycle
cell cycle
negative regulation of protein kinase B signaling cascade
negative regulation of focal adhesion formation
phosphoinositide dephosphorylation
inositol phosphate dephosphorylation
regulation of protein stability
negative regulation of cell migration
negative regulation of cell proliferation
protein amino acid dephosphorylation
cardiac muscle tissue development
platelet-derived growth factor receptor signaling pathway
negative regulation of apoptosis
cell migration
central nervous system development
induction of apoptosis
heart development
cell proliferation
lipid metabolic process

cytosol
nucleus
cytoplasm

protein tyrosine/serine/threonine phosphatase activity
phosphatidylinositol-3-phosphatase activity
protein serine/threonine phosphatase activity
phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity
phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity
PDZ domain binding
magnesium ion binding
protein binding
platelet-derived growth factor receptor binding
inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity
protein tyrosine phosphatase activity
hydrolase activity
lipid binding
phosphoprotein phosphatase activity

2gafD

[pdb]

1.56436
0.000662204

233^LYS 240^TYR 245^ASP 248^ASP 249^ASN 467^HIS

2.7.7.19

mRNA processing
mRNA capping
transcription
regulation of mRNA 3'-end processing
viral transcription
mRNA processing
transcription

transferase activity
methyltransferase activity
mRNA (nucleoside-2'-O-)-methyltransferase activity
transferase activity
polynucleotide adenylyltransferase activity
nucleotide binding
ATP binding

4ptdA

[pdb]

1.58164
0.000714317

116^LYS 118^TYR 163^ARG 180^ASP 181^ASN 198^ASP

4.6.1.13

extracellular region

lipid catabolic process
intracellular signaling cascade
lipid metabolic process

lyase activity
phosphatidylinositol diacylglycerol-lyase activity
phosphoric diester hydrolase activity
phospholipase C activity

1kaeB

[pdb]

1.63244
0.000866667

38^ASP 41^ASP 42^ASN 130^TYR 218^LYS 219^ARG

1.1.1.23

metal ion binding
oxidoreductase activity
zinc ion binding
histidinol dehydrogenase activity
NAD or NADH binding

oxidation reduction
cellular amino acid biosynthetic process
histidine biosynthetic process
metabolic process

1ouuD

[pdb]

1.64029
0.000892241

85^TYR 86^LYS 99^ASP 101^ASP 102^ASN 144^ARG

hemoglobin complex
hemoglobin complex

metal ion binding
iron ion binding
oxygen transporter activity
heme binding
oxygen binding
metal ion binding
iron ion binding
oxygen transporter activity
heme binding
oxygen binding

oxygen transport
transport
oxygen transport
transport

1nikA

[pdb]

1.65073
0.000918491

368^GLU 399^ASP 438^ASP 439^ASN 440^ASP 465^ASN

2.7.7.6

DNA-directed RNA polymerase III complex
nucleus
DNA-directed RNA polymerase I complex
DNA-directed RNA polymerase III complex
DNA-directed RNA polymerase II
core complex
nucleoplasm
nucleus
mitochondrion
DNA-directed RNA polymerase II
core complex
nucleolus
nucleolus
nucleus
DNA-directed RNA polymerase I complex
DNA-directed RNA polymerase II
core complex
nucleoplasm
nucleus
DNA-directed RNA polymerase II
core complex
nucleoplasm
nucleus
DNA-directed RNA polymerase II
core complex
nucleus
DNA-directed RNA polymerase I complex
DNA-directed RNA polymerase III complex
DNA-directed RNA polymerase II
core complex
nucleoplasm
cytoplasm
nucleus
DNA-directed RNA polymerase I complex
DNA-directed RNA polymerase III complex
DNA-directed RNA polymerase II
core complex
nucleoplasm
RNA polymerase complex
nucleus
mitochondrion
DNA-directed RNA polymerase II
core complex
nucleus
DNA-directed RNA polymerase II
core complex
nucleus
DNA-directed RNA polymerase I complex
DNA-directed RNA polymerase III complex
DNA-directed RNA polymerase II
core complex
nucleoplasm

ribonucleoside binding
metal ion binding
zinc ion binding
DNA-directed RNA polymerase activity
DNA binding
metal ion binding
nucleotidyltransferase activity
transferase activity
zinc ion binding
DNA-directed RNA polymerase activity
DNA binding
magnesium ion binding
protein binding
protein binding
protein binding
protein binding
protein binding
metal ion binding
zinc ion binding
DNA-directed RNA polymerase activity
DNA binding
protein binding
metal ion binding
zinc ion binding
DNA-directed RNA polymerase activity
protein dimerization activity
DNA binding
metal ion binding
zinc ion binding
DNA-directed RNA polymerase activity
transcription regulator activity
DNA binding
nucleic acid binding
protein binding
DNA-directed RNA polymerase activity
DNA binding
protein binding
DNA-directed RNA polymerase activity
DNA binding
metal ion binding
nucleotidyltransferase activity
transferase activity
zinc ion binding
DNA-directed RNA polymerase activity
magnesium ion binding
DNA binding
DNA-directed RNA polymerase activity
protein dimerization activity
DNA binding
DNA-directed RNA polymerase activity
protein binding

transcription from RNA polymerase II promoter
transcription
transcription
transcription from RNA polymerase II promoter
RNA elongation from RNA polymerase II promoter
transcription
transcription from RNA polymerase II promoter
regulation of transcription
transcription
transcription from RNA polymerase II promoter
response to DNA damage stimulus
transcription
DNA repair
response to drug
transcription from RNA polymerase II promoter
transcription-coupled nucleotide-excision repair
regulation of transcription
transcription
transcription from RNA polymerase II promoter
transcription
transcription from RNA polymerase II promoter
transcription
DNA-dependent
transcription
transcription from RNA polymerase II promoter
transcription
transcription from RNA polymerase II promoter
transcription
transcription from RNA polymerase II promoter

2oxaA

[pdb]

1.66093
0.000945963

79^ASP 145^ASN 148^ASP 179^ARG 212^TYR 214^LYS

0.0.0.0

peptidase activity
serine-type endopeptidase activity
serine-type peptidase activity
hydrolase activity

proteolysis

1cm8A

[pdb]

1.66693
0.000974586

135^TYR 139^LYS 142^ARG 153^ASP 158^ASN 171^ASP

2.7.11.24

cell cycle arrest
myoblast differentiation
cell cycle
Ras protein signal transduction
intracellular signaling cascade
muscle organ development
signal transduction
DNA damage induced protein phosphorylation
protein amino acid phosphorylation

magnesium ion binding
protein binding
protein serine/threonine kinase activity
metal ion binding
transferase activity
kinase activity
ATP binding
nucleotide binding
MAP kinase activity
protein kinase activity

mitochondrion
cytoplasm

2j63B

[pdb]

1.69786
0.00110293

169^LYS 200^TYR 204^ARG 335^ASP 337^ASN 411^ASP

0.0.0.0

DNA repair

intracellular

lyase activity
endonuclease activity
DNA-(apurinic or apyrimidinic site) lyase activity
nuclease activity
DNA binding

1lp4A

[pdb]

1.7247
0.0012527

138^TYR 142^LYS 148^HIS 156^ASP 161^ASN 175^ASP

2.7.11.1

protein amino acid phosphorylation

transferase activity
kinase activity
ATP binding
protein serine/threonine kinase activity
nucleotide binding
protein kinase activity

2dgaA

[pdb]

1.72535
0.00125273

266^TYR 340^LYS 341^HIS 353^ASN 355^ASP 356^ASP

0.0.0.0

hydrolase activity
acting on glycosyl bonds
hydrolase activity
beta-glucosidase activity
cation binding
hydrolase activity
hydrolyzing O-glycosyl compounds
catalytic activity

metabolic process
carbohydrate metabolic process

1bxcD

[pdb]

1.72624
0.00125276

2^TYR 5^LYS 48^HIS 244^ASP 246^ASN 286^ASP

5.3.1.5

D-xylose metabolic process
pentose-phosphate shunt
carbohydrate metabolic process

cytoplasm

metal ion binding
isomerase activity
magnesium ion binding
xylose isomerase activity

1q7fB

[pdb]

1.7286
0.00125286

766^TYR 769^LYS 792^ASN 793^ASP 808^ASP 1023^ARG

cytoplasm
intracellular
basal cortex
apical cortex

protein binding
translation repressor activity
metal ion binding
zinc ion binding
translation regulator activity

rRNA transcription
regulation of translation
oogenesis
segmentation
asymmetric cell division
negative regulation of cell proliferation
brain development
negative regulation of neuroblast proliferation
neuroblast proliferation
ganglion mother cell fate determination
phagocytosis
engulfment

2zo9C

[pdb]

1.72947
0.00129308

12^ARG 17^LYS 19^TYR 50^ASP 80^ASN 82^ASP

0.0.0.0

hydrolase activity

2rkpA

[pdb]

1.73102
0.00129315

138^TYR 142^LYS 148^HIS 156^ASP 161^ASN 175^ASP

2.7.11.1

Wnt receptor signaling pathway
signal transduction
protein amino acid phosphorylation

plasma membrane
nucleus

protein serine/threonine kinase activity
protein N-terminus binding
transferase activity
kinase activity
ATP binding
nucleotide binding
protein kinase activity
protein binding

1hgxA

[pdb]

1.76681
0.00152195

16^ASN 18^ASP 19^ASP 25^ARG 53^TYR 58^LYS

cytoplasm

metal ion binding
transferase activity
transferring glycosyl groups
transferase activity
magnesium ion binding
hypoxanthine phosphoribosyltransferase activity

purine ribonucleoside salvage
nucleoside metabolic process

2icrA

[pdb]

1.76793
0.00152201

6^HIS 10^ASP 11^ASP 36^ASN 82^TYR 84^LYS

0.0.0.0

protein-chromophore linkage
bioluminescence

1z57A

[pdb]

1.77836
0.00157355

270^TYR 274^LYS 280^HIS 288^ASP 293^ASN 325^ASP

2.7.12.1

cell proliferation
protein amino acid phosphorylation

nucleus

transferase activity
kinase activity
ATP binding
protein tyrosine kinase activity
protein serine/threonine kinase activity
nucleotide binding
non-membrane spanning protein tyrosine kinase activity
protein kinase activity

2e6kB

[pdb]

1.78059
0.00157367

52^ASN 55^ASP 57^ASP 76^TYR 100^LYS 109^HIS

0.0.0.0

metabolic process

transferase activity
transketolase activity
catalytic activity

1bbjH

[pdb]

1.80693
0.00179209

35^HIS 55^ASN 56^ASP 57^ASP 97^LYS 101^TYR

antigen binding

immune response

membrane fraction
extracellular region

3f8uC

[pdb]

1.81909
0.00185194

250^LEU 251^ALA 253^ILE 265^GLU 305^GLY 309^GLU

5.3.4.1

microsome
Golgi membrane
endoplasmic reticulum membrane
MHC class I peptide loading complex
integral to membrane
membrane
endoplasmic reticulum
endoplasmic reticulum
melanosome
endoplasmic reticulum lumen

protein binding
MHC class I protein binding
TAP2 binding
TAP1 binding
peptide antigen binding
unfolded protein binding
peptide antigen-transporting ATPase activity
isomerase activity
protein disulfide isomerase activity
phospholipase C activity
cysteine-type endopeptidase activity
protein binding

retrograde vesicle-mediated transport
Golgi to ER
peptide antigen stabilization
immune response
protein complex assembly
antigen processing and presentation of endogenous peptide antigen via MHC class I
signal transduction
protein retention in ER lumen
protein import into nucleus
cell redox homeostasis
positive regulation of apoptosis

1pvwB

[pdb]

1.82668
0.00197702

20^TYR 189^ASP 190^ASP 192^ASN 200^LYS 201^ARG

4.1.99.12

metal ion binding
manganese ion binding
lyase activity
magnesium ion binding
3,4-dihydroxy-2-butanone-4-phosphate synthase activity

riboflavin biosynthetic process

1olpA

[pdb]

1.83256
0.00197741

67^ASP 77^ASN 92^ASP 99^ARG 190^LYS 195^TYR

0.0.0.0

phospholipase C activity
hydrolase activity
acting on ester bonds
zinc ion binding

3ebyA

[pdb]

1.8325
0.00197741

16^ASP 17^ASP 19^ASN 44^TYR 132^ARG 143^LYS

0.0.0.0

cellular aromatic compound metabolic process
oxidation reduction

oxidoreductase activity
acting on single donors with incorporation of molecular oxygen
incorporation of two atoms of oxygen
catalytic activity

3e3bX

[pdb]

1.83749
0.00204332

139^TYR 143^LYS 149^HIS 157^ASP 162^ASN 176^ASP

2.7.11.1

Wnt receptor signaling pathway
protein amino acid phosphorylation
regulation of cell cycle

protein N-terminus binding
transferase activity
kinase activity
ATP binding
protein serine/threonine kinase activity
nucleotide binding
protein kinase activity
protein binding

2a1aB

[pdb]

1.84489
0.00211166

300^TYR 304^LYS 307^ARG 414^ASP 419^ASN 432^ASP

2.7.11.1

interspecies interaction between organisms
response to virus
negative regulation of cell proliferation
protein amino acid phosphorylation
protein amino acid autophosphorylation
endoplasmic reticulum unfolded protein response
translation
translation
translational initiation
virus-infected cell apoptosis

intracellular
ribosome
cytoplasm
multi-eIF complex
eukaryotic translation initiation factor 2 complex

transferase activity
kinase activity
ATP binding
protein serine/threonine kinase activity
RNA binding
nucleotide binding
protein phosphatase type 2A regulator activity
eukaryotic translation initiation factor 2alpha kinase activity
protein kinase activity
protein binding
translation initiation factor activity
RNA binding
double-stranded RNA binding

2qg7E

[pdb]

1.84789
0.00211187

207^LYS 210^HIS 296^ASP 363^ASP 366^ASN 394^TYR

0.0.0.0

kinase activity

3fi8A

[pdb]

1.85017
0.00218216

211^LYS 213^HIS 288^ASP 317^ASP 320^ASN 357^TYR

0.0.0.0

kinase activity

1dghD

[pdb]

1.85669
0.00225393

144^ASP 218^HIS 231^TYR 233^LYS 335^ASP 338^ASN

1.11.1.6

heme binding
catalase activity
protein homodimerization activity
NADP or NADPH binding
oxidoreductase activity
acting on peroxide as acceptor
metal ion binding
oxidoreductase activity
growth factor activity
iron ion binding
peroxidase activity
aminoacylase activity

hydrogen peroxide catabolic process
UV protection
protein tetramerization
negative regulation of apoptosis
response to reactive oxygen species
oxidation reduction
cell proliferation
response to oxidative stress
positive regulation of NF-kappaB transcription factor activity
negative regulation of NF-kappaB transcription factor activity
hemoglobin metabolic process
positive regulation of phosphoinositide 3-kinase cascade
aerobic respiration
cholesterol metabolic process
triglyceride metabolic process

peroxisome
peroxisomal membrane
mitochondrion

1th4D

[pdb]

1.85667
0.00225393

143^ASP 217^HIS 230^TYR 232^LYS 334^ASP 337^ASN

1.11.1.6

metal ion binding
oxidoreductase activity
growth factor activity
iron ion binding
peroxidase activity
catalase activity
heme binding
aminoacylase activity
oxidoreductase activity
acting on peroxide as acceptor

oxidation reduction
hydrogen peroxide catabolic process
cell proliferation
response to oxidative stress
triglyceride metabolic process
cholesterol metabolic process
aerobic respiration
positive regulation of phosphoinositide 3-kinase cascade
hemoglobin metabolic process
negative regulation of NF-kappaB transcription factor activity
positive regulation of NF-kappaB transcription factor activity

peroxisome
mitochondrion
peroxisomal membrane

2qkwB

[pdb]

1.87169
0.00240246

54^LYS 56^TYR 71^ARG 164^ASP 169^ASN 182^ASP

0.0.0.0

nucleotide binding
kinase activity
protein serine/threonine kinase activity
ATP binding
protein kinase activity

protein amino acid phosphorylation

3c5iA

[pdb]

1.87447
0.00240268

141^LYS 143^HIS 218^ASP 247^ASP 250^ASN 287^TYR

0.0.0.0

kinase activity

1e5mA

[pdb]

1.87904
0.00240304

227^ASP 320^ARG 323^LYS 331^TYR 374^ASN 376^ASP

2.3.1.179

lipid biosynthetic process
fatty acid biosynthetic process
biosynthetic process
metabolic process

transferase activity
acyltransferase activity
beta-ketoacyl-acyl-carrier-protein synthase II activity
transferase activity
transferring acyl groups other than amino-acyl groups
catalytic activity

1x56A

[pdb]

1.88565
0.00248097

337^ASP 339^ASN 340^ASP 368^TYR 370^LYS 374^ARG

6.1.1.22

cytoplasm

ligase activity
ATP binding
aminoacyl-tRNA ligase activity
nucleotide binding
asparagine-tRNA ligase activity
aspartate-tRNA ligase activity
nucleic acid binding

translation
aspartyl-tRNA aminoacylation
asparaginyl-tRNA aminoacylation
tRNA aminoacylation for protein translation

1zrzA

[pdb]

1.88883
0.00256118

253^ARG 256^TYR 258^LYS 330^ASP 373^ASP 374^ASN

2.7.11.13

cytosol
polarisome
nucleus
membrane
endosome
cytoplasm
apical part of cell
apical plasma membrane

membrane organization
cytoskeleton organization
vesicle-mediated transport
establishment or maintenance of epithelial cell apical/basal polarity
protein targeting to membrane
secretion
cell-cell junction organization
signal transduction
protein amino acid phosphorylation
intracellular signaling cascade
eye photoreceptor cell development
establishment of apical/basal cell polarity
actin filament organization
Golgi vesicle budding
cellular response to insulin stimulus
positive regulation of glucose import
regulation of establishment of protein localization

protein binding
phospholipid binding
ATP binding
transferase activity
kinase activity
zinc ion binding
protein serine/threonine kinase activity
nucleotide binding
metal ion binding
diacylglycerol binding
protein kinase C activity
protein kinase activity

1qnzH

[pdb]

1.89074
0.00256134

152^ASN 172^TYR 179^LYS 197^ARG 201^ASP 202^ASP

antigen binding
antigen binding

viral envelope

3e93A

[pdb]

1.89625
0.00264438

132^TYR 139^LYS 142^HIS 150^ASP 155^ASN 168^ASP

2.7.11.24

MP kinase activity
transferase activity
kinase activity
ATP binding
protein serine/threonine kinase activity
nucleotide binding
MAP kinase activity
MAP kinase kinase activity
protein kinase activity
protein binding

cytoplasm
nucleus
cytosol
nucleoplasm
spindle pole
cell

response to stress
protein kinase cascade
Ras protein signal transduction
intracellular signaling cascade
chemotaxis
cell surface receptor linked signal transduction
signal transduction
cell motion
protein amino acid phosphorylation
DNA damage checkpoint
angiogenesis
chondrocyte differentiation
glucose metabolic process
skeletal muscle tissue development
fatty acid oxidation
lipopolysaccharide-mediated signaling pathway
response to muramyl dipeptide
response to lipopolysaccharide
positive regulation of erythrocyte differentiation
positive regulation of transcription from RNA polymerase II promoter

2ixbA

[pdb]

1.89785
0.00264452

150^ASN 355^TYR 361^LYS 363^HIS 376^ASP 380^ASP

hydrolase activity
acting on glycosyl bonds
hydrolase activity
alpha-N-acetylgalactosaminidase activity
oxidoreductase activity
binding
catalytic activity

metabolic process

2odjB

[pdb]

1.8979
0.00264452

271^TYR 273^LYS 275^HIS 364^ASP 398^ASN 400^ASP

basic amino acid transport
ion transport
transport

integral to cell outer membrane
cell outer membrane
integral to membrane
membrane
plasma membrane

porin activity
serine-type peptidase activity
hydrolase activity
peptidase activity

2eklA

[pdb]

1.90018
0.00264472

47^TYR 70^LYS 80^ASP 81^ASN 83^ASP 90^ARG

0.0.0.0

NAD or NADH binding
cofactor binding
oxidoreductase activity
acting on the CH-OH group of donors
NAD or NADP as acceptor
binding
phosphoglycerate dehydrogenase activity
catalytic activity

metabolic process
L-serine biosynthetic process
oxidation reduction

2oqhD

[pdb]

1.90185
0.00273016

91^TYR 197^ASP 199^ASN 224^ASP 273^LYS 297^HIS

0.0.0.0

isomerase activity
catalytic activity

metabolic process

1i2dB

[pdb]

1.90522
0.00273046

200^ASN 234^ASP 236^ASP 378^TYR 383^LYS 386^ARG

2.7.7.4

cysteine biosynthetic process
methionine biosynthetic process
cellular amino acid biosynthetic process
sulfate assimilation

cytoplasm

nucleotidyltransferase activity
transferase activity
ATP binding
catalytic activity
nucleotide binding
sulfate adenylyltransferase (ATP) activity
transferase activity
transferring phosphorus-containing groups
kinase activity

1lf9A

[pdb]

1.91264
0.00281925

182^LYS 187^TYR 227^ARG 331^ASP 332^ASP 333^ASN

0.0.0.0

hydrolase activity
acting on glycosyl bonds
hydrolase activity
glucan 1,4-alpha-glucosidase activity
carbohydrate binding
catalytic activity

metabolic process
polysaccharide metabolic process
carbohydrate metabolic process

2erkA

[pdb]

1.91513
0.00281947

129^TYR 136^LYS 139^HIS 147^ASP 152^ASN 165^ASP

2.7.11.24

nucleoplasm
protein complex
perikaryon
axon part
dendrite cytoplasm
cytosol
nucleus
insoluble fraction
soluble fraction

sensory perception of pain
cell cycle
positive regulation of transcription
positive regulation of translation
response to estrogen stimulus
response to chemical stimulus
positive regulation of cell migration
positive regulation of cell proliferation
protein kinase cascade
intracellular signaling cascade
signal transduction
protein amino acid phosphorylation
nuclear translocation of MAPK
MAPKKK cascade

transferase activity
kinase activity
ATP binding
protein serine/threonine kinase activity
nucleotide binding
MAP kinase activity
mitogen-activated protein kinase kinase kinase binding
protein binding
protein kinase activity

2r7oA

[pdb]

1.92228
0.0029112

242^LYS 326^TYR 457^ARG 520^ASP 631^ASP 633^ASN

2.7.7.48

RNA-directed RNA polymerase activity
RNA binding
nucleotide binding
magnesium ion binding
transferase activity
nucleotidyltransferase activity

viral genome replication
transcription
transcription
RNA-dependent

virion
viral nucleocapsid

2v62B

[pdb]

1.92613
0.00300413

22^ASP 23^ASP 27^ASN 44^TYR 61^LYS 117^ARG

2.7.11.1

membrane
integral to membrane
membrane fraction
endoplasmic reticulum

protein amino acid phosphorylation
protein amino acid autophosphorylation

transferase activity
kinase activity
ATP binding
protein serine/threonine kinase activity
nucleotide binding
protein kinase activity
protein binding

1ftaC

[pdb]

1.93161
0.0030988

209^TYR 218^ASP 220^ASP 229^ARG 230^LYS 267^ASN

3.1.3.11

gluconeogenesis
carbohydrate metabolic process
fructose metabolic process

hydrolase activity
zinc ion binding
catalytic activity
fructose 1,6-bisphosphate 1-phosphatase activity
fructose-2,6-bisphosphate 2-phosphatase activity
phosphoric ester hydrolase activity
identical protein binding
protein binding
magnesium ion binding
metal ion binding

mitochondrion
cytosol

2i6lB

[pdb]

1.93598
0.00309923

134^TYR 141^LYS 144^HIS 152^ASP 157^ASN 171^ASP

2.7.11.24

cell cycle
signal transduction
protein amino acid phosphorylation

cytoplasm

transferase activity
kinase activity
ATP binding
protein serine/threonine kinase activity
nucleotide binding
MAP kinase activity
protein kinase activity
protein binding

1eq2C

[pdb]

1.93636
0.00309927

31^ASP 32^ASN 52^ASP 74^HIS 94^TYR 98^LYS

5.1.3.20

isomerase activity
ADP-glyceromanno-heptose 6-epimerase activity
coenzyme binding
NADP or NADPH binding
binding
catalytic activity
protein binding

lipopolysaccharide biosynthetic process
response to stress
carbohydrate metabolic process
cellular metabolic process
metabolic process

membrane
cytosol
mitochondrion

1nw1B

[pdb]

1.9409
0.00319707

179^LYS 181^HIS 255^ASP 313^ASP 316^ASN 353^TYR

0.0.0.0

kinase activity

1n8vB

[pdb]

1.94368
0.00319735

6^ASP 9^ASP 10^ASN 26^TYR 44^LYS 46^HIS

0.0.0.0

1gq2I

[pdb]

1.95752
0.0034037

31^ASP 90^ASP 92^ASN 194^LYS 196^HIS 558^TYR

1.1.1.40

cytoplasm

metal ion binding
oxidoreductase activity
malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) activity
NAD or NADH binding
oxidoreductase activity
acting on the CH-OH group of donors
NAD or NADP as acceptor
binding
malic enzyme activity
catalytic activity

oxidation reduction
metabolic process
malate metabolic process

2duoB

[pdb]

1.95942
0.00340391

87^TYR 119^LYS 207^ARG 229^ASP 232^ASP 234^ASN

Golgi membrane
integral to membrane
membrane
Golgi apparatus

protein transport
transport

sugar binding
calcium ion binding

2r91A

[pdb]

1.96187
0.00351206

128^ARG 132^LYS 133^TYR 149^ASN 157^ASP 159^ASP

0.0.0.0

lyase activity
catalytic activity

metabolic process

2no4B

[pdb]

1.96243
0.00351213

11^ASP 58^TYR 149^LYS 156^ARG 178^ASN 181^ASP

3.8.1.2

hydrolase activity
(S)-2-haloacid dehalogenase activity
hydrolase activity
acting on acid halide bonds
in C-halide compounds
phosphoglycolate phosphatase activity
catalytic activity

metabolic process

2w1gA

[pdb]

1.97217
0.003625

246^TYR 250^LYS 256^ASP 261^ASN 274^ASP 280^HIS

2.7.11.1

protein binding
transferase activity
kinase activity
ATP binding
protein serine/threonine kinase activity
nucleotide binding
protein kinase activity
ubiquitin protein ligase binding

regulation of protein stability
cell cycle
spindle organization
phosphoinositide-mediated signaling
mitosis
protein amino acid phosphorylation
mitotic cell cycle

spindle
centrosome
nucleus

2zs1B

[pdb]

1.98399
0.0038624

11^VAL 12^ILE 18^VAL 125^ALA 126^HIS 127^ILE

extracellular region
hemoglobin complex
extracellular region
hemoglobin complex
extracellular region
hemoglobin complex
extracellular region
hemoglobin complex

metal ion binding
iron ion binding
oxygen transporter activity
heme binding
oxygen binding
metal ion binding
iron ion binding
oxygen transporter activity
heme binding
oxygen binding
metal ion binding
iron ion binding
oxygen transporter activity
heme binding
oxygen binding
metal ion binding
iron ion binding
oxygen transporter activity
heme binding
oxygen binding

oxygen transport
transport
oxygen transport
transport
oxygen transport
transport
oxygen transport
transport

2fgtA

[pdb]

1.987
0.00386278

71^HIS 80^ASP 81^ASP 82^ASN 125^LYS 172^TYR

metal ion binding
calcium ion binding

plasma membrane
integral to membrane
membrane

3coiA

[pdb]

1.99428
0.00398837

132^TYR 136^LYS 142^HIS 150^ASP 155^ASN 168^ASP

2.7.11.24

MP kinase activity
transferase activity
kinase activity
ATP binding
protein serine/threonine kinase activity
nucleotide binding
MAP kinase activity
protein binding
protein kinase activity

protein kinase cascade
response to stress
cell cycle
Ras protein signal transduction
intracellular signaling cascade
protein amino acid phosphorylation

1ffyA

[pdb]

1.99832
0.00398888

680^TYR 797^LYS 799^ARG 806^ASP 807^ASP 809^ASN

6.1.1.5

cytoplasm

metal ion binding
ligase activity
zinc ion binding
ATP binding
aminoacyl-tRNA ligase activity
nucleotide binding
isoleucine-tRNA ligase activity
catalytic activity

translation
isoleucyl-tRNA aminoacylation
tRNA aminoacylation for protein translation

2zr2B

[pdb]

1.99825
0.00398887

119^ASP 122^ASP 123^ASN 141^ARG 338^TYR 367^LYS

6.1.1.11

cytoplasm

ligase activity
ATP binding
aminoacyl-tRNA ligase activity
nucleotide binding
serine-tRNA ligase activity

translation
seryl-tRNA aminoacylation
tRNA aminoacylation for protein translation
selenocysteine biosynthetic process

1ixkA

[pdb]

2.0043
0.00411667

244^TYR 263^ASP 264^ASN 266^ASP 311^LYS 313^ARG

0.0.0.0

S-adenosylmethionine-dependent methyltransferase activity
RNA binding
methyltransferase activity

rRNA processing

2v05A

[pdb]

2.00529
0.0041168

9^ASP 11^ASP 12^ASN 21^HIS 22^LYS 25^TYR

0.0.0.0

2d40B

[pdb]

2.00739
0.00424656

47^TYR 132^ASN 135^ASP 218^ASP 281^HIS 301^LYS

0.0.0.0

oxidoreductase activity
acting on single donors with incorporation of molecular oxygen
incorporation of two atoms of oxygen

1n44A

[pdb]

2.0101
0.00424693

48^ARG 62^ASP 65^ASN 66^ASP 84^LYS 89^TYR

0.0.0.0

blood coagulation
negative regulation of coagulation
response to organic substance
protein homooligomerization

calcium-dependent phospholipid binding
calcium ion binding
protein binding
receptor tyrosine kinase binding
eukaryotic cell surface binding

1wk1A

[pdb]

2.01029
0.00424695

33^TYR 40^ASP 41^ASP 43^ASN 129^LYS 131^ARG

0.0.0.0

binding

3gfoA

[pdb]

2.01543
0.00438218

90^ASP 92^ASP 93^ASN 101^TYR 137^LYS 140^HIS

0.0.0.0

cobalt ion binding
hydrolase activity
cobalt ion transmembrane transporter activity
ATP binding
nucleotide binding
nucleoside-triphosphatase activity
ATPase activity

cobalt ion transport
ion transport
transport

plasma membrane
membrane
Gram-negative-bacterium-type cell wall

1jc9A

[pdb]

2.01607
0.00438227

94^ARG 98^TYR 121^LYS 147^ASP 150^ASN 151^ASP

cell-cell adhesion
signal transduction

extracellular region

sugar binding
calcium ion binding
receptor binding
metal ion binding

2eixB

[pdb]

2.01951
0.00438276

65^ARG 118^LYS 120^TYR 194^ASN 196^ASP 197^ASP

0.0.0.0

oxidation reduction

oxidoreductase activity
electron carrier activity

11asB

[pdb]

2.02147
0.00452288

77^LYS 78^ARG 93^TYR 219^ASP 220^ASP 233^ASN

6.3.1.1

cellular amino acid biosynthetic process
asparagine biosynthetic process
tRNA aminoacylation for protein translation
translation

cytoplasm

ligase activity
aspartate-ammonia ligase activity
ATP binding
aminoacyl-tRNA ligase activity
nucleotide binding
protein binding

2f49A

[pdb]

2.03429
0.00467026

119^TYR 126^LYS 129^HIS 137^ASP 142^ASN 155^ASP

2.7.11.24

cell division
mitosis
cell cycle
conjugation
negative regulation of MAPKKK cascade
cell cycle arrest
protein amino acid phosphorylation
invasive growth in response to glucose limitation
pheromone-dependent signal transduction involved in conjugation with cellular fusion