The LabelHash Server

Top 100 matches

For each match you can click on the "[pdb]" link to download a PDB file with the matching chain aligned with the motif.
Download a zip file with PDB files for all the matches and the motif itself.

PDB ID	LRMSD / p-value	Matching Residues	EC	Gene Ontology annotations
1pysA	[pdb]	0.399895 2.30313e-05	149^ALA 178^HIS 180^LEU 206^ASP 218^ALA 258^GLN 260^MET	6.1.1.20	cytoplasm cytoplasm	metal ion binding ligase activity ATP binding aminoacyl-tRNA ligase activity RNA binding magnesium ion binding nucleotide binding tRNA binding phenylalanine-tRNA ligase activity metal ion binding ligase activity ATP binding aminoacyl-tRNA ligase activity magnesium ion binding nucleotide binding phenylalanine-tRNA ligase activity	translation tRNA processing phenylalanyl-tRNA aminoacylation translation phenylalanyl-tRNA aminoacylation tRNA aminoacylation for protein translation
1lm5B	[pdb]	1.34261 8.75513e-05	2729^PHE 2735^GLY 2749^GLU 2762^GLN 2765^GLN 2767^THR 2785^TYR		cornified envelope cell junction cytoskeleton cytoplasm mitochondrion basolateral plasma membrane desmosome	keratinocyte differentiation peptide cross-linking epidermis development	protein binding bridging structural molecule activity structural constituent of cytoskeleton protein binding
1ua8A	[pdb]	1.38373 0.000113395	17^HIS 19^SER 43^ARG 94^ALA 140^PHE 152^TYR 158^GLN		periplasmic space outer membrane-bounded periplasmic space	protein binding protein transporter activity	protein transport transport
3bfrA	[pdb]	1.47247 0.000209679	42^TYR 48^THR 52^GLN 54^GLN 70^ARG 74^ALA 81^PHE	1.15.1.1	metal ion binding manganese ion binding oxidoreductase activity superoxide dismutase activity protein binding	mitochondrial matrix mitochondrion	oxidation reduction oxygen and reactive oxygen species metabolic process age-dependent response to oxidative stress during chronological cell aging age-dependent response to reactive oxygen species during chronological cell aging replicative cell aging superoxide metabolic process
1w6jA	[pdb]	1.52167 0.000317052	146^GLU 646^GLN 648^GLN 652^THR 693^ALA 709^ASN 711^PHE	5.4.99.7		isomerase activity lanosterol synthase activity intramolecular transferase activity catalytic activity	lipid biosynthetic process steroid biosynthetic process steroid metabolic process cholesterol biosynthetic process
1xfdD	[pdb]	1.53876 0.000382188	191^ARG 212^GLN 245^ALA 260^ASN 285^TYR 289^SER 301^HIS		cell death proteolysis	dipeptidyl-peptidase activity serine-type peptidase activity	membrane integral to membrane
1xkwA	[pdb]	1.54016 0.000382223	148^GLN 206^ASP 244^GLY 263^GLN 302^THR 306^PHE 325^TYR		cell outer membrane membrane plasma membrane	iron ion binding receptor activity siderophore-iron transmembrane transporter activity transporter activity	iron ion transport ion transport transport siderophore transport
1e6yD	[pdb]	1.55487 0.000434814	4319^GLU 4345^GLN 4419^SER 4420^GLN 4466^PHE 4501^ASN 4507^GLY	2.8.4.1		methanogenesis methanogenesis methanogenesis	transferase activity coenzyme-B sulfoethylthiotransferase activity metal ion binding transferase activity nickel ion binding coenzyme-B sulfoethylthiotransferase activity transferase activity coenzyme-B sulfoethylthiotransferase activity
1el9A	[pdb]	1.59222 0.000646349	53^HIS 56^GLY 60^GLU 69^GLN 144^SER 244^PHE 254^TYR	1.5.3.1	cytoplasm	oxidation reduction tetrahydrofolate metabolic process	oxidoreductase activity sarcosine oxidase activity
2qf9B	[pdb]	1.59634 0.000646529	57^ALA 88^ARG 149^TYR 150^TYR 155^THR 158^HIS 188^GLN	0.0.0.0
2rhqA	[pdb]	1.60339 0.000690239	154^LEU 172^ARG 174^ASP 201^ASN 214^THR 254^ASN 256^VAL	6.1.1.20	cytoplasm cytoplasm	metal ion binding ligase activity ATP binding aminoacyl-tRNA ligase activity RNA binding magnesium ion binding nucleotide binding tRNA binding phenylalanine-tRNA ligase activity metal ion binding ligase activity ATP binding aminoacyl-tRNA ligase activity magnesium ion binding nucleotide binding phenylalanine-tRNA ligase activity	translation tRNA processing phenylalanyl-tRNA aminoacylation translation phenylalanyl-tRNA aminoacylation tRNA aminoacylation for protein translation
2fh1B	[pdb]	1.60783 0.000736304	441^PHE 446^SER 467^GLN 473^GLN 502^GLY 520^TYR 665^ASP		actin filament capping actin filament polymerization actin filament severing barbed-end actin filament capping vesicle-mediated transport	calcium ion binding actin binding protein binding	extracellular region cytosol cytoskeleton cytoplasm actin cytoskeleton lamellipodium
1nphA	[pdb]	1.62063 0.000832415	441^PHE 446^SER 467^GLN 473^GLN 502^GLY 520^TYR 665^ASP		actin filament capping actin filament polymerization actin filament severing barbed-end actin filament capping vesicle-mediated transport	calcium ion binding actin binding protein binding	cytosol extracellular region cytoskeleton cytoplasm lamellipodium
1zovB	[pdb]	1.62067 0.000832417	53^HIS 56^GLY 60^GLU 69^GLN 144^SER 244^PHE 254^TYR	1.5.3.1	cytoplasm	oxidation reduction tetrahydrofolate metabolic process	oxidoreductase activity sarcosine oxidase activity
1vkpB	[pdb]	1.62221 0.000832496	25^THR 57^PHE 102^ARG 318^ASN 369^GLN 371^GLN 373^ALA	3.5.3.12		agmatine deiminase activity hydrolase activity	polyamine biosynthetic process putrescine biosynthetic process
1skbA	[pdb]	1.624 0.000832588	16^GLN 22^SER 23^HIS 28^TYR 37^GLU 376^TRP 380^PHE	3.1.3.8		extracellular region	hydrolase activity 3-phytase activity acid phosphatase activity
1xv2A	[pdb]	1.62744 0.000883689	8^HIS 10^THR 23^ALA 30^GLU 207^GLN 213^ASN 216^PHE	0.0.0.0	acetolactate decarboxylase activity	endoplasmic reticulum membrane	polyol metabolic process
3cvgB	[pdb]	1.63037 0.000883847	49^GLN 169^TYR 175^ASN 203^THR 207^GLN 212^ALA 234^ARG	0.0.0.0
2g5gX	[pdb]	1.63128 0.000937397	45^GLY 56^SER 57^GLN 80^GLU 122^GLN 247^TYR 261^TYR	0.0.0.0
1hm2A	[pdb]	1.6344 0.000937574	224^GLN 230^GLN 232^SER 267^TYR 268^TYR 346^GLY 366^ARG	4.2.2.5	carbohydrate metabolic process	extracellular region	metal ion binding lyase activity calcium ion binding chondroitin AC lyase activity carbohydrate binding carbon-oxygen lyase activity acting on polysaccharides catalytic activity
3decA	[pdb]	1.63826 0.000993943	4^GLN 8^GLN 9^SER 120^GLU 153^TYR 163^TYR 193^TRP	0.0.0.0	beta-galactosidase complex	hydrolase activity hydrolase activity acting on glycosyl bonds cation binding carbohydrate binding beta-galactosidase activity hydrolase activity hydrolyzing O-glycosyl compounds catalytic activity	metabolic process carbohydrate metabolic process
2fknD	[pdb]	1.64695 0.00105335	139^GLN 145^THR 170^GLY 178^GLN 198^ARG 319^TYR 321^ASN	4.2.1.49	cytoplasm	histidine metabolic process histidine catabolic process	lyase activity urocanate hydratase activity
1c28A	[pdb]	1.64954 0.00105351	116^SER 134^ARG 142^GLN 145^HIS 161^TYR 162^TYR 215^TRP	0.0.0.0	extracellular region endoplasmic reticulum extracellular space	hormone activity protein binding receptor binding	protein homooligomerization positive regulation of glucose import positive regulation of fatty acid metabolic process negative regulation of gluconeogenesis positive regulation of I-kappaB kinase/NF-kappaB cascade glucose homeostasis fatty acid oxidation positive regulation of signal transduction response to glucose stimulus fatty acid beta-oxidation glucose metabolic process negative regulation of fat cell differentiation brown fat cell differentiation
1f8iC	[pdb]	1.65109 0.00105361	163^ASN 165^TYR 181^TRP 203^GLN 205^HIS 210^THR 230^ASP	4.1.3.1	cytoplasm	lyase activity isocitrate lyase activity catalytic activity	tricarboxylic acid cycle glyoxylate cycle carboxylic acid metabolic process metabolic process
3ladB	[pdb]	1.66294 0.00118074	386^PHE 401^PHE 411^ASP 429^GLN 454^SER 458^HIS 463^ALA	1.8.1.4	cytoplasm	oxidation reduction glycolysis cell redox homeostasis	oxidoreductase activity dihydrolipoyl dehydrogenase activity FAD binding electron carrier activity
1tdhA	[pdb]	1.66905 0.00124885	4^GLY 8^HIS 12^GLN 50^SER 77^PHE 79^PHE 235^GLU	4.2.99.18	cytoplasm nucleus	hydrolase activity acting on glycosyl bonds protein C-terminus binding lyase activity hydrolase activity catalytic activity DNA binding DNA-(apurinic or apyrimidinic site) lyase activity hydrolase activity hydrolyzing N-glycosyl compounds zinc ion binding damaged DNA binding nucleic acid binding DNA N-glycosylase activity	response to oxidative stress negative regulation of nuclease activity base-excision repair metabolic process response to DNA damage stimulus DNA repair nucleotide-excision repair
1fuiD	[pdb]	1.67137 0.00124901	92^TYR 94^SER 106^ALA 120^TYR 128^HIS 130^GLN 563^ARG	5.3.1.25	cytosol cytoplasm	fucose metabolic process carbohydrate metabolic process fucose catabolic process monosaccharide metabolic process	metal ion binding manganese ion binding isomerase activity L-fucose isomerase activity intramolecular oxidoreductase activity interconverting aldoses and ketoses protein binding
1ihpA	[pdb]	1.67424 0.00132006	16^GLN 22^SER 23^HIS 28^TYR 37^GLU 376^TRP 380^PHE	3.1.3.8		extracellular region	hydrolase activity 3-phytase activity acid phosphatase activity
1rkxB	[pdb]	1.67638 0.00132022	8^GLN 13^PHE 24^TRP 30^GLN 35^THR 85^PHE 349^GLU	0.0.0.0		cellular metabolic process metabolic process	coenzyme binding binding catalytic activity
2ve0A	[pdb]	1.68933 0.00147307	197^PHE 215^HIS 216^SER 245^PHE 251^GLN 257^TRP 287^GLU	0.0.0.0
2vdzA	[pdb]	1.71832 0.00181494	197^PHE 215^HIS 216^SER 245^PHE 251^GLN 257^TRP 287^GLU	0.0.0.0
1x87B	[pdb]	1.72352 0.00190922	137^SER 138^GLN 205^ASN 206^TYR 372^ASP 392^ALA 399^GLN		cytoplasm	histidine metabolic process histidine catabolic process	lyase activity urocanate hydratase activity
2i53A	[pdb]	1.72466 0.00190934	45^THR 54^ALA 82^TYR 87^PHE 191^ASP 263^GLN 264^GLN	0.0.0.0		protein binding	regulation of transcription cell division mitosis cell cycle regulation of transcription DNA-dependent transcription transcription from RNA polymerase II promoter regulation of cyclin-dependent protein kinase activity
3fnbA	[pdb]	1.72575 0.00190944	140^GLU 167^THR 195^GLN 212^ALA 232^PHE 237^TYR 304^GLN	0.0.0.0		proteolysis	serine-type endopeptidase activity
1eokA	[pdb]	1.72996 0.00200827	148^TYR 152^TYR 187^SER 209^GLN 211^GLN 214^GLY 253^ASP	3.2.1.96	extracellular region	hydrolase activity acting on glycosyl bonds hydrolase activity mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity cation binding hydrolase activity hydrolyzing O-glycosyl compounds catalytic activity	metabolic process carbohydrate metabolic process
1g4uS	[pdb]	1.73102 0.00200838	309^ARG 319^GLN 321^THR 322^GLN 338^PHE 347^GLY 512^PHE	3.1.3.48	melanosome plasma membrane membrane cytosol intracellular extracellular region	negative regulation of receptor-mediated endocytosis ruffle organization lamellipodium assembly actin filament polymerization positive regulation of Rho protein signal transduction response to wounding anatomical structure morphogenesis intracellular signaling cascade inflammatory response cell motion small GTPase mediated signal transduction localization within membrane regulation of hydrogen peroxide metabolic process regulation of respiratory burst cell adhesion pathogenesis dephosphorylation protein amino acid dephosphorylation positive regulation of lamellipodium assembly	protein binding GTPase activity GTP binding nucleotide binding GTP-dependent protein binding enzyme binding hydrolase activity GTPase activator activity phosphoprotein phosphatase activity protein tyrosine phosphatase activity phosphatase activity protein binding
2uzzC	[pdb]	1.73351 0.00211193	52^HIS 55^GLY 58^GLU 68^GLN 143^SER 238^PHE 249^TYR			oxidation reduction	oxidoreductase activity oxidoreductase activity acting on the CH-NH group of donors oxygen as acceptor
1bq7B	[pdb]	1.74037 0.00222117	8^GLN 10^THR 154^PHE 159^TYR 164^GLN 172^ASP 179^ALA		cell redox homeostasis cell redox homeostasis	periplasmic space outer membrane-bounded periplasmic space periplasmic space outer membrane-bounded periplasmic space	protein disulfide oxidoreductase activity protein disulfide oxidoreductase activity protein binding
1smsB	[pdb]	1.741 0.00222124	22^GLU 105^SER 107^GLN 109^GLN 176^ALA 223^TYR 226^PHE	1.17.4.1	deoxyribonucleoside diphosphate metabolic process oxidation reduction DNA replication cofactor biosynthetic process deoxyribonucleotide biosynthetic process	nucleus ribonucleoside-diphosphate reductase complex cytoplasm	oxidoreductase activity ribonucleoside-diphosphate reductase activity transition metal ion binding identical protein binding protein binding
1xrhD	[pdb]	1.74148 0.0022213	84^ASP 91^ALA 124^TYR 125^PHE 138^SER 141^GLN 265^GLN	1.1.1.154	cytoplasm	oxidation reduction purine base metabolic process metabolic process	oxidoreductase activity ureidoglycolate dehydrogenase activity
2gseD	[pdb]	1.74275 0.00222144	80^ASP 91^GLN 333^HIS 354^GLY 358^THR 432^ASN 434^PHE		cell differentiation nervous system development multicellular organismal development signal transduction nucleobase nucleoside nucleotide and nucleic acid metabolic process	cytoskeleton cytoplasm cell soma dendrite axon mitochondrion	protein binding dihydropyrimidinase activity hydrolase activity acting on carbon-nitrogen (but not peptide) bonds hydrolase activity
1olpA	[pdb]	1.74501 0.0022217	52^SER 71^ASP 94^ALA 101^PHE 120^TYR 126^HIS 229^GLN	0.0.0.0			phospholipase C activity hydrolase activity acting on ester bonds zinc ion binding
1js1Y	[pdb]	1.74634 0.00222186	223^GLN 254^ARG 259^GLY 262^GLN 266^THR 270^TYR 271^PHE	2.1.3.9	cellular amino acid biosynthetic process arginine biosynthetic process cellular amino acid metabolic process 'de novo' pyrimidine base biosynthetic process	cytoplasm	transferase activity N-acetylornithine carbamoyltransferase activity carboxyl- or carbamoyltransferase activity amino acid binding aspartate carbamoyltransferase activity
2o2kB	[pdb]	1.74732 0.00233601	1035^TRP 1038^GLN 1039^SER 1049^GLU 1054^GLN 1062^PHE 1063^TYR	2.1.1.13	cobalt ion binding metal ion binding cobalamin binding transferase activity zinc ion binding methyltransferase activity methionine synthase activity homocysteine S-methyltransferase activity dihydropteroate synthase activity protein binding	cytoplasm cytosol intracellular	methionine biosynthetic process cellular amino acid biosynthetic process nervous system development cellular metabolic process folic acid and derivative biosynthetic process
1jroD	[pdb]	1.74774 0.00233606	315^ALA 327^GLU 402^THR 404^HIS 455^PHE 615^GLN 622^PHE	0.0.0.0		oxidation reduction oxidation reduction	oxidoreductase activity iron-sulfur cluster binding FAD binding metal ion binding electron carrier activity xanthine oxidase activity xanthine dehydrogenase activity catalytic activity oxidoreductase activity electron carrier activity xanthine oxidase activity xanthine dehydrogenase activity FAD binding molybdenum ion binding iron ion binding 2 iron 2 sulfur cluster binding
1e2tC	[pdb]	1.75245 0.00233663	74^GLY 77^GLU 179^GLN 181^GLN 182^SER 188^ASN 189^PHE	2.3.1.118		metabolic process	transferase activity acyltransferase activity N-hydroxyarylamine O-acetyltransferase activity acetyltransferase activity
1iicA	[pdb]	1.76019 0.00245752	162^GLN 165^SER 204^TYR 282^ARG 287^GLN 423^TYR 451^GLY	2.3.1.97	N-terminal peptidyl-glycine N-myristoylation replicative cell aging N-terminal protein myristoylation	cytoplasm cytosol	transferase activity acyltransferase activity glycylpeptide N-tetradecanoyltransferase activity
1warA	[pdb]	1.76058 0.00258371	49^GLY 91^ASP 150^GLN 189^SER 215^TYR 219^HIS 234^TYR	3.1.3.2	immune response dephosphorylation response to cytokine stimulus bone resorption bone morphogenesis	lysosome cytosol integral to membrane	metal ion binding hydrolase activity iron ion binding acid phosphatase activity
1rzoC	[pdb]	1.76428 0.00258421	1005^GLN 1048^ARG 1092^PHE 1103^ALA 1106^HIS 1109^THR 1115^PHE	3.2.2.22		negative regulation of translation pathogenesis defense response	protein binding hydrolase activity sugar binding nucleotide binding rRNA N-glycosylase activity
1yifC	[pdb]	1.77073 0.0027178	191^TYR 198^TYR 202^ALA 209^GLU 250^SER 263^HIS 292^GLN	3.2.1.37	metabolic process xylan catabolic process carbohydrate metabolic process	plasma membrane membrane	xylan 1,4-beta-xylosidase activity hydrolase activity hydrolase activity acting on glycosyl bonds hydrolase activity hydrolyzing O-glycosyl compounds
2eyqB	[pdb]	1.77171 0.00271794	814^TYR 816^TYR 839^ALA 842^HIS 844^GLN 852^ARG 868^THR			hydrolase activity ATP binding helicase activity DNA binding nucleotide binding ATP-dependent helicase activity transcription factor activity damaged DNA binding nucleic acid binding protein binding	response to DNA damage stimulus DNA repair regulation of transcription DNA-dependent
3ce9D	[pdb]	1.7724 0.00271803	167^SER 264^GLN 269^GLN 273^ALA 297^PHE 298^PHE 313^ARG	0.0.0.0		oxidation reduction aromatic amino acid family biosynthetic process	oxidoreductase activity acting on CH-OH group of donors metal ion binding 3-dehydroquinate synthase activity
2hv2C	[pdb]	1.77617 0.00285815	129^GLN 311^ASP 348^ALA 355^GLN 362^SER 368^PHE 369^TYR	0.0.0.0		N-acetyltransferase activity	metabolic process
1uteA	[pdb]	1.78105 0.00300198	51^GLY 93^ASP 152^GLN 191^SER 217^TYR 221^HIS 236^PHE	3.1.3.2	extracellular region	iron ion transport ion transport transport	metal ion binding hydrolase activity iron ion binding acid phosphatase activity
1yydA	[pdb]	1.78342 0.00300233	22^GLN 25^GLN 27^THR 89^ASN 113^ALA 122^ARG 353^PHE	1.11.1.13	extracellular region	metal ion binding manganese ion binding oxidoreductase activity calcium ion binding iron ion binding peroxidase activity manganese peroxidase activity heme binding	oxidation reduction lignin catabolic process hydrogen peroxide catabolic process response to oxidative stress
2gp4A	[pdb]	1.78772 0.00314979	213^GLN 216^HIS 220^THR 223^PHE 345^ASN 351^GLY 396^ASP	0.0.0.0		Entner-Doudoroff pathway metabolic process	phosphogluconate dehydratase activity catalytic activity
1so0D	[pdb]	1.79157 0.00315039	129^PHE 150^TYR 163^ALA 309^GLN 326^ARG 333^HIS 334^THR	5.1.3.3	carbohydrate metabolic process hexose metabolic process	cytoplasm	isomerase activity aldose 1-epimerase activity carbohydrate binding catalytic activity
3c3lA	[pdb]	1.7937 0.00315072	820^THR 821^GLN 914^GLN 987^TYR 990^PHE 1011^ALA 1017^ARG
1m53A	[pdb]	1.79494 0.00330525	96^TYR 98^SER 110^TYR 149^GLN 152^TRP 165^ARG 208^GLN	0.0.0.0		carbohydrate metabolic process	cation binding catalytic activity
3b5qA	[pdb]	1.79492 0.00330525	28^GLN 36^GLN 41^THR 249^PHE 252^TYR 285^GLY 302^ASP	0.0.0.0		metabolic process	sulfuric ester hydrolase activity catalytic activity
2qi2A	[pdb]	1.79966 0.00330603	144^GLN 155^GLN 158^THR 178^PHE 196^GLY 204^PHE 231^GLU		cell division translation	cytoplasm nucleus	nuclease activity endonuclease activity hydrolase activity metal ion binding
3glyA	[pdb]	1.79959 0.00330601	105^GLY 161^ASN 168^GLN 176^ASP 216^GLN 455^SER 458^TYR	3.2.1.3		hydrolase activity acting on glycosyl bonds hydrolase activity glucan 1,4-alpha-glucosidase activity carbohydrate binding catalytic activity hydrolase activity acting on glycosyl bonds hydrolase activity glucan 1,4-alpha-glucosidase activity carbohydrate binding catalytic activity	metabolic process carbohydrate metabolic process polysaccharide catabolic process polysaccharide metabolic process metabolic process carbohydrate metabolic process polysaccharide catabolic process polysaccharide metabolic process
2nq5A	[pdb]	1.80208 0.00346859	114^THR 236^TYR 237^PHE 286^GLY 321^HIS 344^ASP 499^GLN	2.1.1.14		metal ion binding transferase activity zinc ion binding methyltransferase activity 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity	methionine biosynthetic process cellular amino acid biosynthetic process
2uvcL	[pdb]	1.80221 0.00346861	1116^PHE 1162^GLN 1171^TRP 1173^HIS 1178^THR 1211^ASP 1271^TYR	0.0.0.0	fatty acid synthase complex	metabolic process fatty acid biosynthetic process	transferase activity oxidoreductase activity fatty-acid synthase activity
1hr6A	[pdb]	1.80253 0.00346867	258^ILE 260^GLU 310^ALA 311^VAL 334^GLY 340^ILE 455^TYR	3.4.24.64	hydrolase activity metallopeptidase activity peptidase activity metalloendopeptidase activity metal ion binding zinc ion binding catalytic activity protein binding metal ion binding hydrolase activity zinc ion binding metallopeptidase activity peptidase activity metalloendopeptidase activity catalytic activity protein binding	mitochondrial matrix mitochondrion mitochondrial processing peptidase complex mitochondrial matrix mitochondrion mitochondrial processing peptidase complex	mitochondrial protein processing during import proteolysis mitochondrial protein processing during import proteolysis
1qhwA	[pdb]	1.80531 0.00346914	72^GLY 114^ASP 173^GLN 212^SER 238^TYR 242^HIS 257^TYR	3.1.3.2	bone resorption	lysosome integral to membrane	metal ion binding hydrolase activity iron ion binding acid phosphatase activity
1un2A	[pdb]	1.81438 0.00364106	55^PHE 60^TYR 65^GLN 73^ASP 80^ALA 98^GLN 100^THR		cell redox homeostasis cell redox homeostasis	periplasmic space outer membrane-bounded periplasmic space periplasmic space outer membrane-bounded periplasmic space	protein disulfide oxidoreductase activity protein binding protein disulfide oxidoreductase activity
1peoA	[pdb]	1.81555 0.00382007	493^PHE 497^TYR 502^THR 536^GLN 651^ALA 656^HIS 685^ARG	1.17.4.1	oxidation reduction DNA replication	oxidoreductase activity ATP binding catalytic activity nucleotide binding ribonucleoside-diphosphate reductase activity protein binding	ribonucleoside-diphosphate reductase complex
2ffcA	[pdb]	1.81549 0.00382006	174^GLY 196^ASN 198^TYR 201^THR 202^GLN 211^GLU 258^GLN	0.0.0.0		lyase activity carboxy-lyase activity orotidine-5'-phosphate decarboxylase activity catalytic activity	metabolic process pyrimidine nucleotide biosynthetic process 'de novo' pyrimidine base biosynthetic process
3eu8C	[pdb]	1.81832 0.00382059	47^GLN 59^GLU 280^PHE 284^TYR 360^THR 410^ALA 413^GLN	0.0.0.0
1bwzA	[pdb]	1.81928 0.00382078	72^GLN 130^PHE 154^SER 159^HIS 185^PHE 191^ALA 213^GLU	5.1.1.7	cytoplasm	isomerase activity diaminopimelate epimerase activity	lysine biosynthetic process cellular amino acid biosynthetic process lysine biosynthetic process via diaminopimelate
1sy7A	[pdb]	1.8203 0.00382097	145^ASP 148^GLY 234^GLN 255^PHE 258^THR 300^PHE 543^GLN	1.11.1.6	ascospore wall cell wall extracellular region	heme binding catalase activity metal ion binding oxidoreductase activity iron ion binding peroxidase activity	response to oxidative stress conidium formation oxidation reduction hydrogen peroxide catabolic process
1tedB	[pdb]	1.82247 0.00400899	49^GLN 52^ALA 58^GLU 74^GLN 79^THR 224^PHE 344^PHE	0.0.0.0		biosynthetic process metabolic process	transferase activity transferring acyl groups other than amino-acyl groups acyltransferase activity catalytic activity
1ykjB	[pdb]	1.82612 0.00400972	2078^ALA 2246^ARG 2361^GLN 2365^GLN 2366^THR 2370^TYR 2371^TYR	1.14.13.2		oxidation reduction aromatic compound catabolic process benzoate catabolic process metabolic process	oxidoreductase activity monooxygenase activity 4-hydroxybenzoate 3-monooxygenase activity FAD binding
1s5oA	[pdb]	1.82807 0.0040101	413^GLN 533^SER 534^GLN 537^ALA 544^PHE 545^PHE 561^GLU	2.3.1.7	endoplasmic reticulum peroxisome mitochondrial inner membrane membrane mitochondrion	transferase activity acyltransferase activity carnitine O-acetyltransferase activity	transport fatty acid metabolic process lipid metabolic process energy derivation by oxidation of organic compounds generation of precursor metabolites and energy
1y7bA	[pdb]	1.8287 0.00420699	192^TYR 199^TYR 203^ALA 210^GLU 251^SER 264^HIS 293^GLN	0.0.0.0		carbohydrate metabolic process	hydrolase activity hydrolase activity hydrolyzing O-glycosyl compounds
2ixxA	[pdb]	1.83222 0.00420772	119^ASN 120^PHE 224^THR 241^GLN 244^GLN 257^ALA 300^GLU		cell outer membrane integral to membrane membrane plasma membrane	entry of virus into host cell detection of virus ion transport transport	transporter activity
2q3fB	[pdb]	1.83357 0.004208	50^GLY 138^ARG 160^HIS 174^GLN 200^THR 208^PHE 211^PHE			cytoplasm nucleus	protein binding GTP binding nucleotide binding protein heterodimerization activity
2c61A	[pdb]	1.83675 0.00441495	144^GLN 165^ARG 177^ALA 233^TYR 236^TYR 241^HIS 296^SER		ATP metabolic process proton transport ATP synthesis coupled proton transport plasma membrane ATP synthesis coupled proton transport ion transport transport ATP biosynthetic process	hydrolase activity acting on acid anhydrides catalyzing transmembrane movement of substances hydrogen ion transporting ATP synthase activity rotational mechanism ATP binding metal ion binding hydrogen ion transmembrane transporter activity proton-transporting ATPase activity rotational mechanism	proton-transporting two-sector ATPase complex catalytic domain proton-transporting two-sector ATPase complex
2v3fB	[pdb]	1.83754 0.00441512	200^GLN 207^GLN 208^THR 212^TYR 213^PHE 265^GLY 300^GLU	3.2.1.45	hydrolase activity acting on glycosyl bonds hydrolase activity glucosylceramidase activity cation binding catalytic activity protein binding	lysosomal membrane membrane lysosome	metabolic process lysosome organization sphingolipid metabolic process lipid metabolic process carbohydrate metabolic process
2pygB	[pdb]	1.83779 0.00441518	152^ASP 174^GLY 196^HIS 220^SER 225^GLN 244^TYR 245^TYR	0.0.0.0	alginic acid biosynthetic process	extracellular region extracellular space	isomerase activity calcium ion binding
1sqgA	[pdb]	1.84038 0.00441574	231^GLN 234^SER 236^GLN 243^ALA 266^GLU 372^TYR 423^TYR		cytoplasm	rRNA (cytosine) methyltransferase activity transferase activity methyltransferase activity RNA binding rRNA methyltransferase activity	rRNA methylation rRNA processing regulation of transcription DNA-dependent
2w38A	[pdb]	1.84132 0.00441595	44^GLU 47^GLY 71^GLN 75^GLN 99^THR 127^TYR 129^PHE	0.0.0.0
3dhbA	[pdb]	1.84178 0.00441604	103^SER 107^PHE 124^GLN 137^TYR 173^HIS 207^GLY 211^GLU	0.0.0.0			hydrolase activity
1v0eF	[pdb]	1.84231 0.00463232	330^GLN 527^HIS 528^SER 549^ARG 552^GLY 586^TYR 592^TYR	3.2.1.129		hydrolase activity acting on glycosyl bonds hydrolase activity endo-alpha-sialidase activity hydrolase activity acting on glycosyl bonds hydrolase activity endo-alpha-sialidase activity	metabolic process metabolic process
1xr7A	[pdb]	1.84394 0.0046327	219^SER 379^GLN 388^HIS 421^TRP 426^GLU 457^TYR 460^PHE	3.4.22.29, 3.4.22.28, 3.6.1.15, 2.7.7.48	cytoplasm cytoplasmic vesicle viral capsid virion membrane host cell cytoplasm	interspecies interaction between organisms RNA-protein covalent cross-linking transcription RNA-dependent viral genome replication viral reproduction proteolysis transcription	structural molecule activity helicase activity cysteine-type endopeptidase activity RNA-directed RNA polymerase activity catalytic activity RNA helicase activity RNA binding nucleotide binding hydrolase activity nucleotidyltransferase activity transferase activity cysteine-type peptidase activity peptidase activity ATP binding nucleoside-triphosphatase activity
2q0zX	[pdb]	1.84477 0.00463289	203^PHE 207^TYR 241^THR 256^GLY 274^ARG 278^GLN 279^GLN		ATP binding helicase activity nucleic acid binding nucleotide binding protein binding ATP-dependent helicase activity hydrolase activity nucleoside-triphosphatase activity	U5 snRNP spliceosomal complex nucleus	cis assembly of pre-catalytic spliceosome RNA splicing mRNA processing nuclear mRNA splicing via spliceosome
1u8xX	[pdb]	1.84536 0.00463302	152^ALA 265^TYR 268^TYR 344^GLU 387^GLN 388^GLN 414^SER	3.2.1.122		cobalt ion binding metal ion binding manganese ion binding hydrolase activity acting on glycosyl bonds hydrolase activity nickel ion binding iron ion binding maltose-6'-phosphate glucosidase activity binding hydrolase activity hydrolyzing O-glycosyl compounds catalytic activity	metabolic process carbohydrate metabolic process
2j4cA	[pdb]	1.84637 0.00463325	137^GLU 419^TYR 471^TRP 481^GLN 484^GLN 489^SER 500^TYR	3.1.1.8	catalytic activity beta-amyloid binding enzyme binding cholinesterase activity hydrolase activity carboxylesterase activity	cocaine metabolic process	extracellular region membrane endoplasmic reticulum nuclear envelope lumen
2j4uV	[pdb]	1.848 0.00463362	1119^ASN 1120^PHE 1220^THR 1237^GLN 1240^GLN 1253^ALA 1292^GLU		extracellular region cell outer membrane integral to membrane membrane plasma membrane	iron ion transport ion transport transport cellular iron ion homeostasis entry of virus into host cell detection of virus ion transport transport	metal ion binding hydrolase activity serine-type peptidase activity peptidase activity iron ion binding ferric iron binding transporter activity
1khoA	[pdb]	1.84902 0.00486032	52^SER 71^ASP 94^ALA 101^PHE 120^TYR 126^HIS 229^GLN	3.1.4.3	extracellular region	hemolysis by symbiont of host erythrocytes cytolysis pathogenesis	metal ion binding hydrolase activity zinc ion binding calcium ion binding phosphatidylcholine phospholipase C activity hydrolase activity acting on ester bonds phospholipase C activity
3f0wA	[pdb]	1.84921 0.00486037	57^GLN 157^PHE 159^TYR 185^SER 186^HIS 191^ALA 197^GLU		adherens junction organization nervous system development forebrain development axonogenesis neuroblast proliferation	cytoplasm	protein binding
2e4pB	[pdb]	1.8518 0.00486099	6^ALA 19^GLN 23^ASP 30^PHE 37^PHE 42^GLN 51^SER	0.0.0.0		2 iron 2 sulfur cluster binding iron-sulfur cluster binding metal ion binding iron ion binding oxidoreductase activity electron carrier activity	electron transport chain aromatic compound catabolic process transport oxidation reduction
2of3A	[pdb]	1.85494 0.00486174	633^THR 636^HIS 639^GLN 697^PHE 698^PHE 729^GLU 733^ALA	0.0.0.0		binding protein binding	hermaphrodite genitalia development positive regulation of growth rate pronuclear migration oviposition body morphogenesis embryonic development ending in birth or egg hatching mitotic spindle organization
1n35A	[pdb]	1.85519 0.0048618	459^ARG 536^GLN 537^GLN 539^SER 655^TYR 659^PHE 683^GLY	2.7.7.48	hydrolase activity nucleotidyltransferase activity transferase activity structural molecule activity RNA-directed RNA polymerase activity nucleotide binding RNA binding	transcription RNA-dependent RNA biosynthetic process viral genome replication	virion viral capsid viral nucleocapsid
1syoA	[pdb]	1.85589 0.00509919	316^PHE 317^TYR 325^THR 348^GLN 356^GLN 361^GLY 383^GLU		glycoprotein binding insulin-like growth factor binding mannose binding protein binding receptor activity transporter activity	membrane fraction nucleus nuclear envelope lumen lysosomal membrane integral to membrane membrane lysosome cytoplasm	transport
1lp9F	[pdb]	1.8582 0.00509977	1^GLU 3^ALA 22^SER 24^HIS 72^GLN 90^TYR 91^PHE		Golgi apparatus extracellular region MHC class I protein complex early endosome membrane Golgi membrane membrane MHC class I protein complex integral to membrane early endosome membrane Golgi membrane plasma membrane	immune response antigen processing and presentation of peptide antigen via MHC class I interspecies interaction between organisms immune response antigen processing and presentation of peptide antigen via MHC class I antigen processing and presentation	protein binding protein binding
2h6tA	[pdb]	1.85892 0.00509995	206^GLN 211^ASP 231^ALA 233^GLN 236^SER 252^TYR 298^PHE	3.4.23.24	extracellular region	hydrolase activity peptidase activity aspartic-type endopeptidase activity	proteolysis
2e22A	[pdb]	1.86162 0.00510063	457^ASP 565^GLN 587^TYR 589^PHE 594^THR 596^GLN 628^TRP	0.0.0.0	carbohydrate metabolic process	extracellular region	lyase activity carbohydrate binding carbon-oxygen lyase activity acting on polysaccharides catalytic activity
1lnlC	[pdb]	1.86239 0.00510082	26^GLN 35^GLN 36^SER 73^TYR 138^ARG 202^ALA 250^PHE		extracellular region extracellular space	metal ion binding copper ion binding oxygen transporter activity oxidoreductase activity	oxygen transport transport metabolic process

PDB ID

LRMSD /
p-value

Matching Residues

Gene Ontology annotations

Biological Process

Cellular Component

Molecular Function

1pysA

[pdb]

0.399895
2.30313e-05

149^ALA 178^HIS 180^LEU 206^ASP 218^ALA 258^GLN 260^MET

6.1.1.20

cytoplasm
cytoplasm

metal ion binding
ligase activity
ATP binding
aminoacyl-tRNA ligase activity
RNA binding
magnesium ion binding
nucleotide binding
tRNA binding
phenylalanine-tRNA ligase activity
metal ion binding
ligase activity
ATP binding
aminoacyl-tRNA ligase activity
magnesium ion binding
nucleotide binding
phenylalanine-tRNA ligase activity

translation
tRNA processing
phenylalanyl-tRNA aminoacylation
translation
phenylalanyl-tRNA aminoacylation
tRNA aminoacylation for protein translation

1lm5B

[pdb]

1.34261
8.75513e-05

2729^PHE 2735^GLY 2749^GLU 2762^GLN 2765^GLN 2767^THR 2785^TYR

cornified envelope
cell junction
cytoskeleton
cytoplasm
mitochondrion
basolateral plasma membrane
desmosome

keratinocyte differentiation
peptide cross-linking
epidermis development

protein binding
bridging
structural molecule activity
structural constituent of cytoskeleton
protein binding

1ua8A

[pdb]

1.38373
0.000113395

17^HIS 19^SER 43^ARG 94^ALA 140^PHE 152^TYR 158^GLN

periplasmic space
outer membrane-bounded periplasmic space

protein binding
protein transporter activity

protein transport
transport

3bfrA

[pdb]

1.47247
0.000209679

42^TYR 48^THR 52^GLN 54^GLN 70^ARG 74^ALA 81^PHE

1.15.1.1

metal ion binding
manganese ion binding
oxidoreductase activity
superoxide dismutase activity
protein binding

mitochondrial matrix
mitochondrion

oxidation reduction
oxygen and reactive oxygen species metabolic process
age-dependent response to oxidative stress during chronological cell aging
age-dependent response to reactive oxygen species during chronological cell aging
replicative cell aging
superoxide metabolic process

1w6jA

[pdb]

1.52167
0.000317052

146^GLU 646^GLN 648^GLN 652^THR 693^ALA 709^ASN 711^PHE

5.4.99.7

isomerase activity
lanosterol synthase activity
intramolecular transferase activity
catalytic activity

lipid biosynthetic process
steroid biosynthetic process
steroid metabolic process
cholesterol biosynthetic process

1xfdD

[pdb]

1.53876
0.000382188

191^ARG 212^GLN 245^ALA 260^ASN 285^TYR 289^SER 301^HIS

cell death
proteolysis

dipeptidyl-peptidase activity
serine-type peptidase activity

membrane
integral to membrane

1xkwA

[pdb]

1.54016
0.000382223

148^GLN 206^ASP 244^GLY 263^GLN 302^THR 306^PHE 325^TYR

cell outer membrane
membrane
plasma membrane

iron ion binding
receptor activity
siderophore-iron transmembrane transporter activity
transporter activity

iron ion transport
ion transport
transport
siderophore transport

1e6yD

[pdb]

1.55487
0.000434814

4319^GLU 4345^GLN 4419^SER 4420^GLN 4466^PHE 4501^ASN 4507^GLY

2.8.4.1

methanogenesis
methanogenesis
methanogenesis

transferase activity
coenzyme-B sulfoethylthiotransferase activity
metal ion binding
transferase activity
nickel ion binding
coenzyme-B sulfoethylthiotransferase activity
transferase activity
coenzyme-B sulfoethylthiotransferase activity

1el9A

[pdb]

1.59222
0.000646349

53^HIS 56^GLY 60^GLU 69^GLN 144^SER 244^PHE 254^TYR

1.5.3.1

cytoplasm

oxidation reduction
tetrahydrofolate metabolic process

oxidoreductase activity
sarcosine oxidase activity

2qf9B

[pdb]

1.59634
0.000646529

57^ALA 88^ARG 149^TYR 150^TYR 155^THR 158^HIS 188^GLN

0.0.0.0

2rhqA

[pdb]

1.60339
0.000690239

154^LEU 172^ARG 174^ASP 201^ASN 214^THR 254^ASN 256^VAL

6.1.1.20

cytoplasm
cytoplasm

metal ion binding
ligase activity
ATP binding
aminoacyl-tRNA ligase activity
RNA binding
magnesium ion binding
nucleotide binding
tRNA binding
phenylalanine-tRNA ligase activity
metal ion binding
ligase activity
ATP binding
aminoacyl-tRNA ligase activity
magnesium ion binding
nucleotide binding
phenylalanine-tRNA ligase activity

translation
tRNA processing
phenylalanyl-tRNA aminoacylation
translation
phenylalanyl-tRNA aminoacylation
tRNA aminoacylation for protein translation

2fh1B

[pdb]

1.60783
0.000736304

441^PHE 446^SER 467^GLN 473^GLN 502^GLY 520^TYR 665^ASP

actin filament capping
actin filament polymerization
actin filament severing
barbed-end actin filament capping
vesicle-mediated transport

calcium ion binding
actin binding
protein binding

extracellular region
cytosol
cytoskeleton
cytoplasm
actin cytoskeleton
lamellipodium

1nphA

[pdb]

1.62063
0.000832415

441^PHE 446^SER 467^GLN 473^GLN 502^GLY 520^TYR 665^ASP

actin filament capping
actin filament polymerization
actin filament severing
barbed-end actin filament capping
vesicle-mediated transport

calcium ion binding
actin binding
protein binding

cytosol
extracellular region
cytoskeleton
cytoplasm
lamellipodium

1zovB

[pdb]

1.62067
0.000832417

53^HIS 56^GLY 60^GLU 69^GLN 144^SER 244^PHE 254^TYR

1.5.3.1

cytoplasm

oxidation reduction
tetrahydrofolate metabolic process

oxidoreductase activity
sarcosine oxidase activity

1vkpB

[pdb]

1.62221
0.000832496

25^THR 57^PHE 102^ARG 318^ASN 369^GLN 371^GLN 373^ALA

3.5.3.12

agmatine deiminase activity
hydrolase activity

polyamine biosynthetic process
putrescine biosynthetic process

1skbA

[pdb]

1.624
0.000832588

16^GLN 22^SER 23^HIS 28^TYR 37^GLU 376^TRP 380^PHE

3.1.3.8

extracellular region

hydrolase activity
3-phytase activity
acid phosphatase activity

1xv2A

[pdb]

1.62744
0.000883689

8^HIS 10^THR 23^ALA 30^GLU 207^GLN 213^ASN 216^PHE

0.0.0.0

acetolactate decarboxylase activity

endoplasmic reticulum membrane

polyol metabolic process

3cvgB

[pdb]

1.63037
0.000883847

49^GLN 169^TYR 175^ASN 203^THR 207^GLN 212^ALA 234^ARG

0.0.0.0

2g5gX

[pdb]

1.63128
0.000937397

45^GLY 56^SER 57^GLN 80^GLU 122^GLN 247^TYR 261^TYR

0.0.0.0

1hm2A

[pdb]

1.6344
0.000937574

224^GLN 230^GLN 232^SER 267^TYR 268^TYR 346^GLY 366^ARG

4.2.2.5

carbohydrate metabolic process

extracellular region

metal ion binding
lyase activity
calcium ion binding
chondroitin AC lyase activity
carbohydrate binding
carbon-oxygen lyase activity
acting on polysaccharides
catalytic activity

3decA

[pdb]

1.63826
0.000993943

4^GLN 8^GLN 9^SER 120^GLU 153^TYR 163^TYR 193^TRP

0.0.0.0

beta-galactosidase complex

hydrolase activity
hydrolase activity
acting on glycosyl bonds
cation binding
carbohydrate binding
beta-galactosidase activity
hydrolase activity
hydrolyzing O-glycosyl compounds
catalytic activity

metabolic process
carbohydrate metabolic process

2fknD

[pdb]

1.64695
0.00105335

139^GLN 145^THR 170^GLY 178^GLN 198^ARG 319^TYR 321^ASN

4.2.1.49

cytoplasm

histidine metabolic process
histidine catabolic process

lyase activity
urocanate hydratase activity

1c28A

[pdb]

1.64954
0.00105351

116^SER 134^ARG 142^GLN 145^HIS 161^TYR 162^TYR 215^TRP

0.0.0.0

extracellular region
endoplasmic reticulum
extracellular space

hormone activity
protein binding
receptor binding

protein homooligomerization
positive regulation of glucose import
positive regulation of fatty acid metabolic process
negative regulation of gluconeogenesis
positive regulation of I-kappaB kinase/NF-kappaB cascade
glucose homeostasis
fatty acid oxidation
positive regulation of signal transduction
response to glucose stimulus
fatty acid beta-oxidation
glucose metabolic process
negative regulation of fat cell differentiation
brown fat cell differentiation

1f8iC

[pdb]

1.65109
0.00105361

163^ASN 165^TYR 181^TRP 203^GLN 205^HIS 210^THR 230^ASP

4.1.3.1

cytoplasm

lyase activity
isocitrate lyase activity
catalytic activity

tricarboxylic acid cycle
glyoxylate cycle
carboxylic acid metabolic process
metabolic process

3ladB

[pdb]

1.66294
0.00118074

386^PHE 401^PHE 411^ASP 429^GLN 454^SER 458^HIS 463^ALA

1.8.1.4

cytoplasm

oxidation reduction
glycolysis
cell redox homeostasis

oxidoreductase activity
dihydrolipoyl dehydrogenase activity
FAD binding
electron carrier activity

1tdhA

[pdb]

1.66905
0.00124885

4^GLY 8^HIS 12^GLN 50^SER 77^PHE 79^PHE 235^GLU

4.2.99.18

cytoplasm
nucleus

hydrolase activity
acting on glycosyl bonds
protein C-terminus binding
lyase activity
hydrolase activity
catalytic activity
DNA binding
DNA-(apurinic or apyrimidinic site) lyase activity
hydrolase activity
hydrolyzing N-glycosyl compounds
zinc ion binding
damaged DNA binding
nucleic acid binding
DNA N-glycosylase activity

response to oxidative stress
negative regulation of nuclease activity
base-excision repair
metabolic process
response to DNA damage stimulus
DNA repair
nucleotide-excision repair

1fuiD

[pdb]

1.67137
0.00124901

92^TYR 94^SER 106^ALA 120^TYR 128^HIS 130^GLN 563^ARG

5.3.1.25

cytosol
cytoplasm

fucose metabolic process
carbohydrate metabolic process
fucose catabolic process
monosaccharide metabolic process

metal ion binding
manganese ion binding
isomerase activity
L-fucose isomerase activity
intramolecular oxidoreductase activity
interconverting aldoses and ketoses
protein binding

1ihpA

[pdb]

1.67424
0.00132006

16^GLN 22^SER 23^HIS 28^TYR 37^GLU 376^TRP 380^PHE

3.1.3.8

extracellular region

hydrolase activity
3-phytase activity
acid phosphatase activity

1rkxB

[pdb]

1.67638
0.00132022

8^GLN 13^PHE 24^TRP 30^GLN 35^THR 85^PHE 349^GLU

0.0.0.0

cellular metabolic process
metabolic process

coenzyme binding
binding
catalytic activity

2ve0A

[pdb]

1.68933
0.00147307

197^PHE 215^HIS 216^SER 245^PHE 251^GLN 257^TRP 287^GLU

0.0.0.0

2vdzA

[pdb]

1.71832
0.00181494

197^PHE 215^HIS 216^SER 245^PHE 251^GLN 257^TRP 287^GLU

0.0.0.0

1x87B

[pdb]

1.72352
0.00190922

137^SER 138^GLN 205^ASN 206^TYR 372^ASP 392^ALA 399^GLN

cytoplasm

histidine metabolic process
histidine catabolic process

lyase activity
urocanate hydratase activity

2i53A

[pdb]

1.72466
0.00190934

45^THR 54^ALA 82^TYR 87^PHE 191^ASP 263^GLN 264^GLN

0.0.0.0

protein binding

regulation of transcription
cell division
mitosis
cell cycle
regulation of transcription
DNA-dependent
transcription
transcription from RNA polymerase II promoter
regulation of cyclin-dependent protein kinase activity

3fnbA

[pdb]

1.72575
0.00190944

140^GLU 167^THR 195^GLN 212^ALA 232^PHE 237^TYR 304^GLN

0.0.0.0

proteolysis

serine-type endopeptidase activity

1eokA

[pdb]

1.72996
0.00200827

148^TYR 152^TYR 187^SER 209^GLN 211^GLN 214^GLY 253^ASP

3.2.1.96

extracellular region

hydrolase activity
acting on glycosyl bonds
hydrolase activity
mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity
cation binding
hydrolase activity
hydrolyzing O-glycosyl compounds
catalytic activity

metabolic process
carbohydrate metabolic process

1g4uS

[pdb]

1.73102
0.00200838

309^ARG 319^GLN 321^THR 322^GLN 338^PHE 347^GLY 512^PHE

3.1.3.48

melanosome
plasma membrane
membrane
cytosol
intracellular
extracellular region

negative regulation of receptor-mediated endocytosis
ruffle organization
lamellipodium assembly
actin filament polymerization
positive regulation of Rho protein signal transduction
response to wounding
anatomical structure morphogenesis
intracellular signaling cascade
inflammatory response
cell motion
small GTPase mediated signal transduction
localization within membrane
regulation of hydrogen peroxide metabolic process
regulation of respiratory burst
cell adhesion
pathogenesis
dephosphorylation
protein amino acid dephosphorylation
positive regulation of lamellipodium assembly

protein binding
GTPase activity
GTP binding
nucleotide binding
GTP-dependent protein binding
enzyme binding
hydrolase activity
GTPase activator activity
phosphoprotein phosphatase activity
protein tyrosine phosphatase activity
phosphatase activity
protein binding

2uzzC

[pdb]

1.73351
0.00211193

52^HIS 55^GLY 58^GLU 68^GLN 143^SER 238^PHE 249^TYR

oxidation reduction

oxidoreductase activity
oxidoreductase activity
acting on the CH-NH group of donors
oxygen as acceptor

1bq7B

[pdb]

1.74037
0.00222117

8^GLN 10^THR 154^PHE 159^TYR 164^GLN 172^ASP 179^ALA

cell redox homeostasis
cell redox homeostasis

periplasmic space
outer membrane-bounded periplasmic space
periplasmic space
outer membrane-bounded periplasmic space

protein disulfide oxidoreductase activity
protein disulfide oxidoreductase activity
protein binding

1smsB

[pdb]

1.741
0.00222124

22^GLU 105^SER 107^GLN 109^GLN 176^ALA 223^TYR 226^PHE

1.17.4.1

deoxyribonucleoside diphosphate metabolic process
oxidation reduction
DNA replication
cofactor biosynthetic process
deoxyribonucleotide biosynthetic process

nucleus
ribonucleoside-diphosphate reductase complex
cytoplasm

oxidoreductase activity
ribonucleoside-diphosphate reductase activity
transition metal ion binding
identical protein binding
protein binding

1xrhD

[pdb]

1.74148
0.0022213

84^ASP 91^ALA 124^TYR 125^PHE 138^SER 141^GLN 265^GLN

1.1.1.154

cytoplasm

oxidation reduction
purine base metabolic process
metabolic process

oxidoreductase activity
ureidoglycolate dehydrogenase activity

2gseD

[pdb]

1.74275
0.00222144

80^ASP 91^GLN 333^HIS 354^GLY 358^THR 432^ASN 434^PHE

cell differentiation
nervous system development
multicellular organismal development
signal transduction
nucleobase
nucleoside
nucleotide and nucleic acid metabolic process

cytoskeleton
cytoplasm
cell soma
dendrite
axon
mitochondrion

protein binding
dihydropyrimidinase activity
hydrolase activity
acting on carbon-nitrogen (but not peptide) bonds
hydrolase activity

1olpA

[pdb]

1.74501
0.0022217

52^SER 71^ASP 94^ALA 101^PHE 120^TYR 126^HIS 229^GLN

0.0.0.0

phospholipase C activity
hydrolase activity
acting on ester bonds
zinc ion binding

1js1Y

[pdb]

1.74634
0.00222186

223^GLN 254^ARG 259^GLY 262^GLN 266^THR 270^TYR 271^PHE

2.1.3.9

cellular amino acid biosynthetic process
arginine biosynthetic process
cellular amino acid metabolic process
'de novo' pyrimidine base biosynthetic process

cytoplasm

transferase activity
N-acetylornithine carbamoyltransferase activity
carboxyl- or carbamoyltransferase activity
amino acid binding
aspartate carbamoyltransferase activity

2o2kB

[pdb]

1.74732
0.00233601

1035^TRP 1038^GLN 1039^SER 1049^GLU 1054^GLN 1062^PHE 1063^TYR

2.1.1.13

cobalt ion binding
metal ion binding
cobalamin binding
transferase activity
zinc ion binding
methyltransferase activity
methionine synthase activity
homocysteine S-methyltransferase activity
dihydropteroate synthase activity
protein binding

cytoplasm
cytosol
intracellular

methionine biosynthetic process
cellular amino acid biosynthetic process
nervous system development
cellular metabolic process
folic acid and derivative biosynthetic process

1jroD

[pdb]

1.74774
0.00233606

315^ALA 327^GLU 402^THR 404^HIS 455^PHE 615^GLN 622^PHE

0.0.0.0

oxidation reduction
oxidation reduction

oxidoreductase activity
iron-sulfur cluster binding
FAD binding
metal ion binding
electron carrier activity
xanthine oxidase activity
xanthine dehydrogenase activity
catalytic activity
oxidoreductase activity
electron carrier activity
xanthine oxidase activity
xanthine dehydrogenase activity
FAD binding
molybdenum ion binding
iron ion binding
2 iron
2 sulfur cluster binding

1e2tC

[pdb]

1.75245
0.00233663

74^GLY 77^GLU 179^GLN 181^GLN 182^SER 188^ASN 189^PHE

2.3.1.118

metabolic process

transferase activity
acyltransferase activity
N-hydroxyarylamine O-acetyltransferase activity
acetyltransferase activity

1iicA

[pdb]

1.76019
0.00245752

162^GLN 165^SER 204^TYR 282^ARG 287^GLN 423^TYR 451^GLY

2.3.1.97

N-terminal peptidyl-glycine N-myristoylation
replicative cell aging
N-terminal protein myristoylation

cytoplasm
cytosol

transferase activity
acyltransferase activity
glycylpeptide N-tetradecanoyltransferase activity

1warA

[pdb]

1.76058
0.00258371

49^GLY 91^ASP 150^GLN 189^SER 215^TYR 219^HIS 234^TYR

3.1.3.2

immune response
dephosphorylation
response to cytokine stimulus
bone resorption
bone morphogenesis

lysosome
cytosol
integral to membrane

metal ion binding
hydrolase activity
iron ion binding
acid phosphatase activity

1rzoC

[pdb]

1.76428
0.00258421

1005^GLN 1048^ARG 1092^PHE 1103^ALA 1106^HIS 1109^THR 1115^PHE

3.2.2.22

negative regulation of translation
pathogenesis
defense response

protein binding
hydrolase activity
sugar binding
nucleotide binding
rRNA N-glycosylase activity

1yifC

[pdb]

1.77073
0.0027178

191^TYR 198^TYR 202^ALA 209^GLU 250^SER 263^HIS 292^GLN

3.2.1.37

metabolic process
xylan catabolic process
carbohydrate metabolic process

plasma membrane
membrane

xylan 1,4-beta-xylosidase activity
hydrolase activity
hydrolase activity
acting on glycosyl bonds
hydrolase activity
hydrolyzing O-glycosyl compounds

2eyqB

[pdb]

1.77171
0.00271794

814^TYR 816^TYR 839^ALA 842^HIS 844^GLN 852^ARG 868^THR

hydrolase activity
ATP binding
helicase activity
DNA binding
nucleotide binding
ATP-dependent helicase activity
transcription factor activity
damaged DNA binding
nucleic acid binding
protein binding

response to DNA damage stimulus
DNA repair
regulation of transcription
DNA-dependent

3ce9D

[pdb]

1.7724
0.00271803

167^SER 264^GLN 269^GLN 273^ALA 297^PHE 298^PHE 313^ARG

0.0.0.0

oxidation reduction
aromatic amino acid family biosynthetic process

oxidoreductase activity
acting on CH-OH group of donors
metal ion binding
3-dehydroquinate synthase activity

2hv2C

[pdb]

1.77617
0.00285815

129^GLN 311^ASP 348^ALA 355^GLN 362^SER 368^PHE 369^TYR

0.0.0.0

N-acetyltransferase activity

metabolic process

1uteA

[pdb]

1.78105
0.00300198

51^GLY 93^ASP 152^GLN 191^SER 217^TYR 221^HIS 236^PHE

3.1.3.2

extracellular region

iron ion transport
ion transport
transport

metal ion binding
hydrolase activity
iron ion binding
acid phosphatase activity

1yydA

[pdb]

1.78342
0.00300233

22^GLN 25^GLN 27^THR 89^ASN 113^ALA 122^ARG 353^PHE

1.11.1.13

extracellular region

metal ion binding
manganese ion binding
oxidoreductase activity
calcium ion binding
iron ion binding
peroxidase activity
manganese peroxidase activity
heme binding

oxidation reduction
lignin catabolic process
hydrogen peroxide catabolic process
response to oxidative stress

2gp4A

[pdb]

1.78772
0.00314979

213^GLN 216^HIS 220^THR 223^PHE 345^ASN 351^GLY 396^ASP

0.0.0.0

Entner-Doudoroff pathway
metabolic process

phosphogluconate dehydratase activity
catalytic activity

1so0D

[pdb]

1.79157
0.00315039

129^PHE 150^TYR 163^ALA 309^GLN 326^ARG 333^HIS 334^THR

5.1.3.3

carbohydrate metabolic process
hexose metabolic process

cytoplasm

isomerase activity
aldose 1-epimerase activity
carbohydrate binding
catalytic activity

3c3lA

[pdb]

1.7937
0.00315072

820^THR 821^GLN 914^GLN 987^TYR 990^PHE 1011^ALA 1017^ARG

1m53A

[pdb]

1.79494
0.00330525

96^TYR 98^SER 110^TYR 149^GLN 152^TRP 165^ARG 208^GLN

0.0.0.0

carbohydrate metabolic process

cation binding
catalytic activity

3b5qA

[pdb]

1.79492
0.00330525

28^GLN 36^GLN 41^THR 249^PHE 252^TYR 285^GLY 302^ASP

0.0.0.0

metabolic process

sulfuric ester hydrolase activity
catalytic activity

2qi2A

[pdb]

1.79966
0.00330603

144^GLN 155^GLN 158^THR 178^PHE 196^GLY 204^PHE 231^GLU

cell division
translation

cytoplasm
nucleus

nuclease activity
endonuclease activity
hydrolase activity
metal ion binding

3glyA

[pdb]

1.79959
0.00330601

105^GLY 161^ASN 168^GLN 176^ASP 216^GLN 455^SER 458^TYR

3.2.1.3

hydrolase activity
acting on glycosyl bonds
hydrolase activity
glucan 1,4-alpha-glucosidase activity
carbohydrate binding
catalytic activity
hydrolase activity
acting on glycosyl bonds
hydrolase activity
glucan 1,4-alpha-glucosidase activity
carbohydrate binding
catalytic activity

metabolic process
carbohydrate metabolic process
polysaccharide catabolic process
polysaccharide metabolic process
metabolic process
carbohydrate metabolic process
polysaccharide catabolic process
polysaccharide metabolic process

2nq5A

[pdb]

1.80208
0.00346859

114^THR 236^TYR 237^PHE 286^GLY 321^HIS 344^ASP 499^GLN

2.1.1.14

metal ion binding
transferase activity
zinc ion binding
methyltransferase activity
5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity

methionine biosynthetic process
cellular amino acid biosynthetic process

2uvcL

[pdb]

1.80221
0.00346861

1116^PHE 1162^GLN 1171^TRP 1173^HIS 1178^THR 1211^ASP 1271^TYR

0.0.0.0

fatty acid synthase complex

metabolic process
fatty acid biosynthetic process

transferase activity
oxidoreductase activity
fatty-acid synthase activity

1hr6A

[pdb]

1.80253
0.00346867

258^ILE 260^GLU 310^ALA 311^VAL 334^GLY 340^ILE 455^TYR

3.4.24.64

hydrolase activity
metallopeptidase activity
peptidase activity
metalloendopeptidase activity
metal ion binding
zinc ion binding
catalytic activity
protein binding
metal ion binding
hydrolase activity
zinc ion binding
metallopeptidase activity
peptidase activity
metalloendopeptidase activity
catalytic activity
protein binding

mitochondrial matrix
mitochondrion
mitochondrial processing peptidase complex
mitochondrial matrix
mitochondrion
mitochondrial processing peptidase complex

mitochondrial protein processing during import
proteolysis
mitochondrial protein processing during import
proteolysis

1qhwA

[pdb]

1.80531
0.00346914

72^GLY 114^ASP 173^GLN 212^SER 238^TYR 242^HIS 257^TYR

3.1.3.2

bone resorption

lysosome
integral to membrane

metal ion binding
hydrolase activity
iron ion binding
acid phosphatase activity

1un2A

[pdb]

1.81438
0.00364106

55^PHE 60^TYR 65^GLN 73^ASP 80^ALA 98^GLN 100^THR

cell redox homeostasis
cell redox homeostasis

periplasmic space
outer membrane-bounded periplasmic space
periplasmic space
outer membrane-bounded periplasmic space

protein disulfide oxidoreductase activity
protein binding
protein disulfide oxidoreductase activity

1peoA

[pdb]

1.81555
0.00382007

493^PHE 497^TYR 502^THR 536^GLN 651^ALA 656^HIS 685^ARG

1.17.4.1

oxidation reduction
DNA replication

oxidoreductase activity
ATP binding
catalytic activity
nucleotide binding
ribonucleoside-diphosphate reductase activity
protein binding

ribonucleoside-diphosphate reductase complex

2ffcA

[pdb]

1.81549
0.00382006

174^GLY 196^ASN 198^TYR 201^THR 202^GLN 211^GLU 258^GLN

0.0.0.0

lyase activity
carboxy-lyase activity
orotidine-5'-phosphate decarboxylase activity
catalytic activity

metabolic process
pyrimidine nucleotide biosynthetic process
'de novo' pyrimidine base biosynthetic process

3eu8C

[pdb]

1.81832
0.00382059

47^GLN 59^GLU 280^PHE 284^TYR 360^THR 410^ALA 413^GLN

0.0.0.0

1bwzA

[pdb]

1.81928
0.00382078

72^GLN 130^PHE 154^SER 159^HIS 185^PHE 191^ALA 213^GLU

5.1.1.7

cytoplasm

isomerase activity
diaminopimelate epimerase activity

lysine biosynthetic process
cellular amino acid biosynthetic process
lysine biosynthetic process via diaminopimelate

1sy7A

[pdb]

1.8203
0.00382097

145^ASP 148^GLY 234^GLN 255^PHE 258^THR 300^PHE 543^GLN

1.11.1.6

ascospore wall
cell wall
extracellular region

heme binding
catalase activity
metal ion binding
oxidoreductase activity
iron ion binding
peroxidase activity

response to oxidative stress
conidium formation
oxidation reduction
hydrogen peroxide catabolic process

1tedB

[pdb]

1.82247
0.00400899

49^GLN 52^ALA 58^GLU 74^GLN 79^THR 224^PHE 344^PHE

0.0.0.0

biosynthetic process
metabolic process

transferase activity
transferring acyl groups other than amino-acyl groups
acyltransferase activity
catalytic activity

1ykjB

[pdb]

1.82612
0.00400972

2078^ALA 2246^ARG 2361^GLN 2365^GLN 2366^THR 2370^TYR 2371^TYR

1.14.13.2

oxidation reduction
aromatic compound catabolic process
benzoate catabolic process
metabolic process

oxidoreductase activity
monooxygenase activity
4-hydroxybenzoate 3-monooxygenase activity
FAD binding

1s5oA

[pdb]

1.82807
0.0040101

413^GLN 533^SER 534^GLN 537^ALA 544^PHE 545^PHE 561^GLU

2.3.1.7

endoplasmic reticulum
peroxisome
mitochondrial inner membrane
membrane
mitochondrion

transferase activity
acyltransferase activity
carnitine O-acetyltransferase activity

transport
fatty acid metabolic process
lipid metabolic process
energy derivation by oxidation of organic compounds
generation of precursor metabolites and energy

1y7bA

[pdb]

1.8287
0.00420699

192^TYR 199^TYR 203^ALA 210^GLU 251^SER 264^HIS 293^GLN

0.0.0.0

carbohydrate metabolic process

hydrolase activity
hydrolase activity
hydrolyzing O-glycosyl compounds

2ixxA

[pdb]

1.83222
0.00420772

119^ASN 120^PHE 224^THR 241^GLN 244^GLN 257^ALA 300^GLU

cell outer membrane
integral to membrane
membrane
plasma membrane

entry of virus into host cell
detection of virus
ion transport
transport

transporter activity

2q3fB

[pdb]

1.83357
0.004208

50^GLY 138^ARG 160^HIS 174^GLN 200^THR 208^PHE 211^PHE

cytoplasm
nucleus

protein binding
GTP binding
nucleotide binding
protein heterodimerization activity

2c61A

[pdb]

1.83675
0.00441495

144^GLN 165^ARG 177^ALA 233^TYR 236^TYR 241^HIS 296^SER

ATP metabolic process
proton transport
ATP synthesis coupled proton transport
plasma membrane ATP synthesis coupled proton transport
ion transport
transport
ATP biosynthetic process

hydrolase activity
acting on acid anhydrides
catalyzing transmembrane movement of substances
hydrogen ion transporting ATP synthase activity
rotational mechanism
ATP binding
metal ion binding
hydrogen ion transmembrane transporter activity
proton-transporting ATPase activity
rotational mechanism

proton-transporting two-sector ATPase complex
catalytic domain
proton-transporting two-sector ATPase complex

2v3fB

[pdb]

1.83754
0.00441512

200^GLN 207^GLN 208^THR 212^TYR 213^PHE 265^GLY 300^GLU

3.2.1.45

hydrolase activity
acting on glycosyl bonds
hydrolase activity
glucosylceramidase activity
cation binding
catalytic activity
protein binding

lysosomal membrane
membrane
lysosome

metabolic process
lysosome organization
sphingolipid metabolic process
lipid metabolic process
carbohydrate metabolic process

2pygB

[pdb]

1.83779
0.00441518

152^ASP 174^GLY 196^HIS 220^SER 225^GLN 244^TYR 245^TYR

0.0.0.0

alginic acid biosynthetic process

extracellular region
extracellular space

isomerase activity
calcium ion binding

1sqgA

[pdb]

1.84038
0.00441574

231^GLN 234^SER 236^GLN 243^ALA 266^GLU 372^TYR 423^TYR

cytoplasm

rRNA (cytosine) methyltransferase activity
transferase activity
methyltransferase activity
RNA binding
rRNA methyltransferase activity

rRNA methylation
rRNA processing
regulation of transcription
DNA-dependent

2w38A

[pdb]

1.84132
0.00441595

44^GLU 47^GLY 71^GLN 75^GLN 99^THR 127^TYR 129^PHE

0.0.0.0

3dhbA

[pdb]

1.84178
0.00441604

103^SER 107^PHE 124^GLN 137^TYR 173^HIS 207^GLY 211^GLU

0.0.0.0

hydrolase activity

1v0eF

[pdb]

1.84231
0.00463232

330^GLN 527^HIS 528^SER 549^ARG 552^GLY 586^TYR 592^TYR

3.2.1.129

hydrolase activity
acting on glycosyl bonds
hydrolase activity
endo-alpha-sialidase activity
hydrolase activity
acting on glycosyl bonds
hydrolase activity
endo-alpha-sialidase activity

metabolic process
metabolic process

1xr7A

[pdb]

1.84394
0.0046327

219^SER 379^GLN 388^HIS 421^TRP 426^GLU 457^TYR 460^PHE

3.4.22.29, 3.4.22.28, 3.6.1.15, 2.7.7.48

cytoplasm
cytoplasmic vesicle
viral capsid
virion
membrane
host cell cytoplasm

interspecies interaction between organisms
RNA-protein covalent cross-linking
transcription
RNA-dependent
viral genome replication
viral reproduction
proteolysis
transcription

structural molecule activity
helicase activity
cysteine-type endopeptidase activity
RNA-directed RNA polymerase activity
catalytic activity
RNA helicase activity
RNA binding
nucleotide binding
hydrolase activity
nucleotidyltransferase activity
transferase activity
cysteine-type peptidase activity
peptidase activity
ATP binding
nucleoside-triphosphatase activity

2q0zX

[pdb]

1.84477
0.00463289

203^PHE 207^TYR 241^THR 256^GLY 274^ARG 278^GLN 279^GLN

ATP binding
helicase activity
nucleic acid binding
nucleotide binding
protein binding
ATP-dependent helicase activity
hydrolase activity
nucleoside-triphosphatase activity

U5 snRNP
spliceosomal complex
nucleus

cis assembly of pre-catalytic spliceosome
RNA splicing
mRNA processing
nuclear mRNA splicing
via spliceosome

1u8xX

[pdb]

1.84536
0.00463302

152^ALA 265^TYR 268^TYR 344^GLU 387^GLN 388^GLN 414^SER

3.2.1.122

cobalt ion binding
metal ion binding
manganese ion binding
hydrolase activity
acting on glycosyl bonds
hydrolase activity
nickel ion binding
iron ion binding
maltose-6'-phosphate glucosidase activity
binding
hydrolase activity
hydrolyzing O-glycosyl compounds
catalytic activity

metabolic process
carbohydrate metabolic process

2j4cA

[pdb]

1.84637
0.00463325

137^GLU 419^TYR 471^TRP 481^GLN 484^GLN 489^SER 500^TYR

3.1.1.8

catalytic activity
beta-amyloid binding
enzyme binding
cholinesterase activity
hydrolase activity
carboxylesterase activity

cocaine metabolic process

extracellular region
membrane
endoplasmic reticulum
nuclear envelope lumen

2j4uV

[pdb]

1.848
0.00463362

1119^ASN 1120^PHE 1220^THR 1237^GLN 1240^GLN 1253^ALA 1292^GLU

extracellular region
cell outer membrane
integral to membrane
membrane
plasma membrane

iron ion transport
ion transport
transport
cellular iron ion homeostasis
entry of virus into host cell
detection of virus
ion transport
transport

metal ion binding
hydrolase activity
serine-type peptidase activity
peptidase activity
iron ion binding
ferric iron binding
transporter activity

1khoA

[pdb]

1.84902
0.00486032

52^SER 71^ASP 94^ALA 101^PHE 120^TYR 126^HIS 229^GLN

3.1.4.3

extracellular region

hemolysis by symbiont of host erythrocytes
cytolysis
pathogenesis

metal ion binding
hydrolase activity
zinc ion binding
calcium ion binding
phosphatidylcholine phospholipase C activity
hydrolase activity
acting on ester bonds
phospholipase C activity

3f0wA

[pdb]

1.84921
0.00486037

57^GLN 157^PHE 159^TYR 185^SER 186^HIS 191^ALA 197^GLU

adherens junction organization
nervous system development
forebrain development
axonogenesis
neuroblast proliferation

cytoplasm

protein binding

2e4pB

[pdb]

1.8518
0.00486099

6^ALA 19^GLN 23^ASP 30^PHE 37^PHE 42^GLN 51^SER

0.0.0.0

2 iron
2 sulfur cluster binding
iron-sulfur cluster binding
metal ion binding
iron ion binding
oxidoreductase activity
electron carrier activity

electron transport chain
aromatic compound catabolic process
transport
oxidation reduction

2of3A

[pdb]

1.85494
0.00486174

633^THR 636^HIS 639^GLN 697^PHE 698^PHE 729^GLU 733^ALA

0.0.0.0

binding
protein binding

hermaphrodite genitalia development
positive regulation of growth rate
pronuclear migration
oviposition
body morphogenesis
embryonic development ending in birth or egg hatching
mitotic spindle organization

1n35A

[pdb]

1.85519
0.0048618

459^ARG 536^GLN 537^GLN 539^SER 655^TYR 659^PHE 683^GLY

2.7.7.48

hydrolase activity
nucleotidyltransferase activity
transferase activity
structural molecule activity
RNA-directed RNA polymerase activity
nucleotide binding
RNA binding

transcription
RNA-dependent
RNA biosynthetic process
viral genome replication

virion
viral capsid
viral nucleocapsid

1syoA

[pdb]

1.85589
0.00509919

316^PHE 317^TYR 325^THR 348^GLN 356^GLN 361^GLY 383^GLU

glycoprotein binding
insulin-like growth factor binding
mannose binding
protein binding
receptor activity
transporter activity

membrane fraction
nucleus
nuclear envelope lumen
lysosomal membrane
integral to membrane
membrane
lysosome
cytoplasm

transport

1lp9F

[pdb]

1.8582
0.00509977

1^GLU 3^ALA 22^SER 24^HIS 72^GLN 90^TYR 91^PHE

Golgi apparatus
extracellular region
MHC class I protein complex
early endosome membrane
Golgi membrane
membrane
MHC class I protein complex
integral to membrane
early endosome membrane
Golgi membrane
plasma membrane

immune response
antigen processing and presentation of peptide antigen via MHC class I
interspecies interaction between organisms
immune response
antigen processing and presentation of peptide antigen via MHC class I
antigen processing and presentation

protein binding
protein binding

2h6tA

[pdb]

1.85892
0.00509995

206^GLN 211^ASP 231^ALA 233^GLN 236^SER 252^TYR 298^PHE

3.4.23.24

extracellular region

hydrolase activity
peptidase activity
aspartic-type endopeptidase activity

proteolysis

2e22A

[pdb]

1.86162
0.00510063

457^ASP 565^GLN 587^TYR 589^PHE 594^THR 596^GLN 628^TRP

0.0.0.0

carbohydrate metabolic process

extracellular region

lyase activity
carbohydrate binding
carbon-oxygen lyase activity
acting on polysaccharides
catalytic activity

1lnlC

[pdb]

1.86239
0.00510082

26^GLN 35^GLN 36^SER 73^TYR 138^ARG 202^ALA 250^PHE

extracellular region
extracellular space

metal ion binding
copper ion binding
oxygen transporter activity
oxidoreductase activity

oxygen transport
transport
metabolic process