The LabelHash Server

Top 100 matches

For each match you can click on the "[pdb]" link to download a PDB file with the matching chain aligned with the motif.
Download a zip file with PDB files for all the matches and the motif itself.

PDB ID	LRMSD / p-value	Matching Residues	EC	Gene Ontology annotations
1adjB	[pdb]	0.135874 2.23026e-05	81^GLU 83^THR 112^ARG 130^GLU 264^TYR 311^ARG	6.1.1.21	cytoplasm	ligase activity ATP binding aminoacyl-tRNA ligase activity nucleotide binding histidine-tRNA ligase activity	translation histidyl-tRNA aminoacylation tRNA aminoacylation for protein translation
1httD	[pdb]	0.361492 6.85666e-05	83^GLU 85^THR 113^ARG 131^GLU 264^TYR 311^ARG	6.1.1.21	ATP binding histidine-tRNA ligase activity ligase activity aminoacyl-tRNA ligase activity nucleotide binding ligase activity ATP binding aminoacyl-tRNA ligase activity nucleotide binding histidine-tRNA ligase activity ligase activity ATP binding aminoacyl-tRNA ligase activity nucleotide binding histidine-tRNA ligase activity	cytoplasm cytoplasm cytoplasm	histidyl-tRNA aminoacylation translation tRNA aminoacylation for protein translation translation histidyl-tRNA aminoacylation tRNA aminoacylation for protein translation translation histidyl-tRNA aminoacylation tRNA aminoacylation for protein translation
2q09A	[pdb]	0.898837 0.000135665	38^ARG 57^GLN 133^GLU 136^THR 165^LEU 374^ASP		cytoplasm	histidine metabolic process histidine catabolic process to glutamate and formamide histidine catabolic process	metal ion binding hydrolase activity zinc ion binding iron ion binding imidazolonepropionase activity hydrolase activity acting on carbon-nitrogen (but not peptide) bonds in cyclic amides hydrolase activity acting on carbon-nitrogen (but not peptide) bonds
2oogB	[pdb]	0.906773 0.000144909	60^ARG 89^ASP 159^ARG 170^THR 180^GLU 225^LEU			glycerophosphodiester phosphodiesterase activity phosphoric diester hydrolase activity glycerophosphodiester phosphodiesterase activity phosphoric diester hydrolase activity	lipid metabolic process glycerol metabolic process lipid metabolic process glycerol metabolic process
2pt3A	[pdb]	1.03429 0.000300749	269^LEU 360^ARG 393^ASP 555^ASP 557^THR 570^ASN	1.11.1.7	extracellular region extracellular space	metal ion binding oxidoreductase activity calcium ion binding iron ion binding peroxidase activity heme binding	oxidation reduction hydrogen peroxide catabolic process defense response to bacterium response to oxidative stress
3db9A	[pdb]	1.05143 0.000339961	24^ARG 72^ASP 77^THR 80^LEU 85^ASP 94^ARG
2yvdD	[pdb]	1.06482 0.00038837	67^ARG 145^SER 162^ASP 188^THR 341^TYR 402^GLU		cytoplasm	metal ion binding hydrolase activity zinc ion binding endonuclease activity nuclease activity RNA binding	rRNA processing
1wf4e	[pdb]	1.06975 0.000416411	36^ALA 76^GLY 81^GLU 87^TYR 151^SER 506^LEU	0.0.0.0	ATP binding ATP binding nucleotide binding protein binding unfolded protein binding	cytoplasm cytoplasm	protein folding protein folding cellular protein metabolic process protein refolding
2zyqA	[pdb]	1.08526 0.00048124	8^TYR 138^THR 140^GLU 219^GLU 249^ASN 254^SER	0.0.0.0		oxidation reduction cellular aromatic compound metabolic process aromatic compound catabolic process	oxidoreductase activity acting on single donors with incorporation of molecular oxygen incorporation of two atoms of oxygen oxidoreductase activity biphenyl-2,3-diol 1,2-dioxygenase activity ferrous iron binding catalytic activity iron ion binding
1yz6A	[pdb]	1.09143 0.000518181	201^ARG 211^ASP 225^ARG 227^ASP 229^THR 234^TYR		eukaryotic translation initiation factor 2 complex	translation translational initiation	translation initiation factor activity RNA binding
3d8bA	[pdb]	1.10162 0.00055852	464^SER 500^ASP 527^GLN 545^THR 550^GLU 563^LEU			ATP metabolic process	hydrolase activity magnesium ion binding metal ion binding ATP binding nucleotide binding nucleoside-triphosphatase activity
3f0eA	[pdb]	1.11598 0.000649116	80^ARG 97^ASP 99^THR 107^LEU 128^ARG 149^GLU	4.6.1.12		isoprenoid biosynthetic process terpenoid biosynthetic process	metal ion binding lyase activity 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
1uzgB	[pdb]	1.11678 0.000649156	120^GLN 126^GLU 198^THR 201^ASP 220^SER 262^LEU	3.4.21.91, 2.7.7.48, 2.1.1.56	hydrolase activity nucleotidyltransferase activity transferase activity ATP binding structural molecule activity helicase activity RNA-directed RNA polymerase activity nucleotide binding mRNA (guanine-N7-)-methyltransferase activity ATP-dependent helicase activity serine-type endopeptidase activity catalytic activity double-stranded RNA binding RNA helicase activity RNA binding nucleic acid binding methyltransferase activity	membrane viral envelope viral capsid viral nucleocapsid virion integral to membrane virion part	transcription RNA-dependent viral genome replication viral infectious cycle RNA metabolic process viral reproduction methylation
1dbiA	[pdb]	1.12611 0.000751807	34^GLU 83^GLU 97^THR 103^ARG 126^SER 235^LEU		extracellular region	metal ion binding hydrolase activity serine-type peptidase activity peptidase activity calcium ion binding serine-type endopeptidase activity	proteolysis
2pifA	[pdb]	1.12612 0.000751807	23^ARG 71^ASP 76^THR 79^LEU 84^ASP 93^ARG
1qe0A	[pdb]	1.13561 0.000806135	80^GLU 82^THR 112^ARG 130^GLU 262^TYR 312^ARG	6.1.1.21	cytoplasm	ligase activity ATP binding aminoacyl-tRNA ligase activity nucleotide binding histidine-tRNA ligase activity	translation histidyl-tRNA aminoacylation tRNA aminoacylation for protein translation
4pgaB	[pdb]	1.15275 0.000925808	68^GLU 75^LEU 102^THR 104^GLU 139^ASN 167^SER	3.5.1.38	asparagine metabolic process cellular amino acid metabolic process	hydrolase activity glutamin-(asparagin-)ase activity asparaginase activity	periplasmic space
2v4wA	[pdb]	1.15585 0.000990867	273^TYR 291^THR 294^ASP 319^ASP 369^LYS 405^SER	2.3.3.10	mitochondrion mitochondrial matrix mitochondrial inner membrane	sterol biosynthetic process lipid biosynthetic process cholesterol biosynthetic process steroid biosynthetic process isoprenoid biosynthetic process metabolic process response to peptide hormone stimulus response to drug response to nutrient	transferase activity hydroxymethylglutaryl-CoA synthase activity catalytic activity
2jd4B	[pdb]	1.15912 0.000991093	2721^ARG 2758^LEU 2788^GLU 2797^THR 2799^ASP 2855^GLN		basement membrane proteinaceous extracellular matrix extracellular region basal lamina extracellular matrix laminin-1 complex	cell adhesion establishment of epithelial cell apical/basal polarity tissue development cell surface receptor linked signal transduction morphogenesis of an epithelial sheet regulation of embryonic development regulation of cell migration regulation of cell adhesion branching involved in lung morphogenesis branching involved in salivary gland morphogenesis	protein binding extracellular matrix structural constituent receptor binding
3pga4	[pdb]	1.16236 0.00105984	68^GLU 75^LEU 102^THR 104^GLU 139^ASN 167^SER	3.5.1.38	asparagine metabolic process cellular amino acid metabolic process	hydrolase activity glutamin-(asparagin-)ase activity asparaginase activity	periplasmic space
1k5gI	[pdb]	1.16348 0.00105992	40^SER 66^GLU 91^LEU 98^THR 125^GLU 131^ASN		perinuclear region of cytoplasm nuclear pore chromatin cytoplasm melanosome nucleus cytosol nucleoplasm cytoplasm nuclear membrane cytosol cytoplasm nucleus centrosome	positive regulation of transcription DNA-dependent androgen receptor signaling pathway signal transduction mitosis mitotic spindle organization protein export from nucleus RNA export from nucleus DNA metabolic process interspecies interaction between organisms protein transport transport nucleocytoplasmic transport intracellular protein transport kinetochore organization Ran protein signal transduction chromatin silencing at centromere chromosome segregation nucleocytoplasmic transport chromatin silencing at telomere signal transduction intracellular transport positive regulation of mitotic centrosome separation spindle organization	protein binding androgen receptor binding transcription coactivator activity GTPase activity GTP binding chromatin binding nucleotide binding Ran GTPase activator activity GTPase activator activity GTPase activator activity Ran GTPase binding GDP-dissociation inhibitor activity protein binding
1pznB	[pdb]	1.1684 0.00113242	135^GLU 151^LEU 204^ARG 216^GLN 238^ASP 282^THR		ATP binding DNA binding nucleotide binding sequence-specific DNA binding nucleoside-triphosphatase activity DNA-dependent ATPase activity protein binding damaged DNA binding	intracellular	response to DNA damage stimulus DNA recombination DNA repair DNA metabolic process
1iq0A	[pdb]	1.16856 0.00113243	108^GLU 111^SER 136^LEU 333^ARG 347^GLU 349^THR	6.1.1.19	arginyl-tRNA aminoacylation translation tRNA aminoacylation for protein translation translation arginyl-tRNA aminoacylation tRNA aminoacylation for protein translation	cytoplasm cytoplasm	nucleotide binding ATP binding arginine-tRNA ligase activity ligase activity aminoacyl-tRNA ligase activity ATP binding arginine-tRNA ligase activity aminoacyl-tRNA ligase activity nucleotide binding ligase activity
1abrA	[pdb]	1.17705 0.00120885	24^MET 53^LEU 63^ARG 65^ASN 69^LEU 153^SER	0.0.0.0	cellular_component	hydrolase activity sugar binding rRNA N-glycosylase activity galactose binding	negative regulation of translation pathogenesis defense response positive regulation of endocytosis
1wovA	[pdb]	1.17904 0.00120901	20^GLU 22^THR 138^LYS 210^GLU 225^LEU 233^SER	1.14.99.3		metal ion binding oxidoreductase activity iron ion binding heme oxygenase (decyclizing) activity	oxidation reduction photosynthesis heme oxidation
2j22A	[pdb]	1.18311 0.00128869	24^GLN 88^SER 91^ASP 101^GLU 104^THR 119^LEU	0.0.0.0			cell adhesion
1d2vC	[pdb]	1.18446 0.00128881	254^LEU 345^ARG 378^ASP 539^ASP 541^THR 555^ASN	1.11.1.7	lysosome nucleus extracellular space	metal ion binding oxidoreductase activity calcium ion binding iron ion binding peroxidase activity chromatin binding heme binding	response to oxidative stress oxidation reduction hydrogen peroxide catabolic process defense response anti-apoptosis low-density lipoprotein particle remodeling
1z7nB	[pdb]	1.1923 0.0013724	84^LEU 86^TYR 112^ARG 130^GLU 283^GLN 294^LEU		cellular amino acid biosynthetic process histidine biosynthetic process histidyl-tRNA aminoacylation tRNA aminoacylation for protein translation translation cellular amino acid biosynthetic process histidine biosynthetic process	cytoplasm cytoplasm	nucleotide binding ATP binding ATP binding histidine-tRNA ligase activity aminoacyl-tRNA ligase activity nucleotide binding transferase activity transferring glycosyl groups transferase activity ATP phosphoribosyltransferase activity
1reqC	[pdb]	1.19785 0.00145938	129^LEU 513^VAL 516^ALA 532^SER 553^ILE 558^LYS	5.4.99.2		cobalt ion binding cobalamin binding isomerase activity methylmalonyl-CoA mutase activity metal ion binding intramolecular transferase activity catalytic activity cobalt ion binding metal ion binding cobalamin binding isomerase activity methylmalonyl-CoA mutase activity intramolecular transferase activity catalytic activity	lactate fermentation to propionate and acetate metabolic process metabolic process
2isaB	[pdb]	1.20135 0.0014597	65^THR 81^ASP 116^TYR 217^SER 261^GLN 294^GLU	0.0.0.0		oxidation reduction response to oxidative stress hydrogen peroxide catabolic process	oxidoreductase activity peroxidase activity catalase activity heme binding iron ion binding metal ion binding
2f8sA	[pdb]	1.20563 0.00155014	103^ASP 106^THR 112^ASP 116^SER 160^LYS 298^LEU	0.0.0.0			nucleic acid binding
1m9nB	[pdb]	1.20634 0.0015502	438^LYS 461^ASP 493^ASP 497^THR 520^LEU 551^ARG	3.5.4.10, 2.1.2.3		hydrolase activity transferase activity catalytic activity phosphoribosylaminoimidazolecarboxamide formyltransferase activity IMP cyclohydrolase activity	purine nucleotide biosynthetic process IMP biosynthetic process
2jizE	[pdb]	1.21049 0.00164423	59^ARG 119^GLU 237^LYS 266^ILE 288^ASP 291^THR	3.6.3.14	ATP catabolic process proton transport ion transport transport ATP biosynthetic process ATP metabolic process ATP synthesis coupled proton transport lipid metabolic process negative regulation of cell adhesion involved in substrate-bound cell migration lipid metabolic process embryonic development ATP metabolic process proton transport ATP synthesis coupled proton transport ion transport transport ATP biosynthetic process proton transport ion transport transport ATP biosynthetic process ATP synthesis coupled proton transport	mitochondrial inner membrane mitochondrion proton-transporting ATP synthase complex catalytic core F(1) membrane proton-transporting two-sector ATPase complex catalytic domain proton-transporting two-sector ATPase complex mitochondrion proton-transporting ATP synthase complex catalytic core F(1) proton-transporting two-sector ATPase complex catalytic domain proton-transporting two-sector ATPase complex mitochondrial inner membrane membrane mitochondrial inner membrane mitochondrion proton-transporting ATP synthase complex catalytic core F(1) membrane	protein binding metal ion binding hydrolase activity hydrogen ion transmembrane transporter activity ATP binding proton-transporting ATPase activity rotational mechanism hydrogen ion transporting ATP synthase activity rotational mechanism nucleoside-triphosphatase activity hydrolase activity acting on acid anhydrides catalyzing transmembrane movement of substances hydrogen-exporting ATPase activity phosphorylative mechanism nucleotide binding ATP binding nucleotide binding proton-transporting ATPase activity rotational mechanism hydrogen ion transporting ATP synthase activity rotational mechanism hydrolase activity acting on acid anhydrides catalyzing transmembrane movement of substances protein binding metal ion binding hydrogen ion transmembrane transporter activity protein binding metal ion binding hydrogen ion transmembrane transporter activity proton-transporting ATPase activity rotational mechanism hydrogen ion transporting ATP synthase activity rotational mechanism
3cpgA	[pdb]	1.2109 0.00164427	24^GLU 26^THR 33^LEU 69^ASP 86^LYS 97^ARG	0.0.0.0
1w27A	[pdb]	1.21119 0.0016443	136^ARG 161^LEU 197^ARG 205^ASP 262^THR 383^ASP	4.3.1.24	cytoplasm	lyase activity ammonia-lyase activity ammonia ligase activity catalytic activity	phenylpropanoid metabolic process biosynthetic process L-phenylalanine catabolic process
2eryA	[pdb]	1.21171 0.00164435	67^LEU 80^GLU 85^THR 87^GLU 150^LYS 176^ARG		GTP binding nucleotide binding GTPase activity protein binding	plasma membrane membrane endoplasmic reticulum intracellular	small GTPase mediated signal transduction positive regulation of cell migration cellular process Ras protein signal transduction
3chjA	[pdb]	1.214 0.00164458	82^ARG 91^ARG 113^THR 115^GLU 156^ASP 240^LEU	0.0.0.0	calcium-dependent phospholipid binding calcium ion binding calcium-dependent phospholipid binding calcium ion binding	cell projection flagellum cilium	cell projection organization
3gf8A	[pdb]	1.21569 0.00164474	63^TYR 109^SER 111^ASP 113^THR 124^ASP 237^ARG	0.0.0.0
1n35A	[pdb]	1.21944 0.00174247	696^SER 700^GLU 704^THR 709^GLU 719^LEU 770^LYS	2.7.7.48	hydrolase activity nucleotidyltransferase activity transferase activity structural molecule activity RNA-directed RNA polymerase activity nucleotide binding RNA binding	transcription RNA-dependent RNA biosynthetic process viral genome replication	virion viral capsid viral nucleocapsid
1qycA	[pdb]	1.22105 0.00174263	134^LYS 217^LEU 267^SER 275^ASP 277^THR 280^GLU	0.0.0.0		metabolic process regulation of nitrogen utilization	transcription repressor activity binding catalytic activity
1ug9A	[pdb]	1.22156 0.00174268	41^THR 57^GLU 71^GLU 117^LEU 138^SER 182^ASN	0.0.0.0		carbohydrate catabolic process polysaccharide metabolic process carbohydrate metabolic process	catalytic activity carbohydrate binding hydrolase activity hydrolyzing O-glycosyl compounds glucan 1,4-alpha-glucosidase activity
1kmyA	[pdb]	1.22227 0.00174276	8^TYR 139^THR 141^GLU 214^GLU 243^ASN 248^SER	1.13.11.39		metal ion binding oxidoreductase activity acting on single donors with incorporation of molecular oxygen incorporation of two atoms of oxygen oxidoreductase activity iron ion binding biphenyl-2,3-diol 1,2-dioxygenase activity dioxygenase activity ferrous iron binding catalytic activity	oxidation reduction aromatic compound catabolic process xenobiotic catabolic process cellular aromatic compound metabolic process
1gw7K	[pdb]	1.22695 0.00184451	2018^GLN 2028^ARG 2253^ASP 2256^THR 2379^TYR 2385^GLU	0.0.0.0		structural molecule activity	virion viral capsid
3exg1	[pdb]	1.22711 0.00184453	37^TYR 76^PRO 98^ALA 235^VAL 237^ASN 255^LYS	0.0.0.0	mitochondrial matrix mitochondrion intracellular membrane-bounded organelle mitochondrial matrix mitochondrion	oxidation reduction glycolysis oxidation reduction glycolysis tricarboxylic acid cycle metabolic process metabolic process	oxidoreductase activity pyruvate dehydrogenase (acetyl-transferring) activity oxidoreductase activity acting on the aldehyde or oxo group of donors disulfide as acceptor pyruvate dehydrogenase activity oxidoreductase activity pyruvate dehydrogenase (acetyl-transferring) activity catalytic activity protein binding
2r5eB	[pdb]	1.23251 0.00195057	190^THR 195^LEU 200^ASP 222^GLU 252^SER 315^ASN	0.0.0.0		biosynthetic process	transferase activity transaminase activity pyridoxal phosphate binding 1-aminocyclopropane-1-carboxylate synthase activity transferase activity transferring nitrogenous groups catalytic activity
2azkB	[pdb]	1.26109 0.00240645	110^ASN 126^ASP 131^THR 134^GLU 140^SER 171^LEU	0.0.0.0		isoprenoid biosynthetic process	transferase activity geranyltranstransferase activity farnesyltranstransferase activity dimethylallyltranstransferase activity
3fe1B	[pdb]	1.26117 0.00240646	17^TYR 206^THR 208^ASP 210^SER 234^ASP 353^GLN			ATP binding nucleotide binding	response to stress response to unfolded protein
1pbkA	[pdb]	1.2623 0.00240661	110^LYS 114^SER 136^THR 146^ASP 162^LEU 217^GLU	5.2.1.8	cytoplasm nucleus	isomerase activity peptidyl-prolyl cis-trans isomerase activity FK506 binding receptor activity	protein folding
1vkhA	[pdb]	1.26292 0.00240668	44^GLU 46^THR 72^GLU 81^ASN 90^SER 247^TYR	3.5.1.9		hydrolase activity arylformamidase activity	tryptophan catabolic process NAD biosynthetic process
2b6nA	[pdb]	1.26709 0.00253295	14^ASP 16^ARG 26^THR 29^ASP 82^TYR 253^LYS	0.0.0.0		identical protein binding peptidase activity serine-type endopeptidase activity serine-type peptidase activity hydrolase activity identical protein binding peptidase activity serine-type endopeptidase activity	negative regulation of catalytic activity proteolysis negative regulation of catalytic activity proteolysis
2h0bA	[pdb]	1.26737 0.00253299	299^ASN 305^SER 307^GLU 309^THR 333^LEU 447^GLU		cell adhesion	membrane integral to membrane	metal ion binding protein binding calcium ion binding
1fj7A	[pdb]	1.27292 0.00253372	5^LEU 13^GLU 15^THR 39^SER 51^ASP 58^ARG			nucleolus nucleus	telomeric DNA binding RNA binding DNA binding nucleic acid binding nucleotide binding
1a4qA	[pdb]	1.27425 0.00266584	226^SER 254^LYS 271^GLU 273^THR 275^GLU 315^LEU	3.2.1.18	hydrolase activity acting on glycosyl bonds hydrolase activity exo-alpha-sialidase activity	metabolic process carbohydrate metabolic process	virion membrane apical plasma membrane virion integral to membrane membrane plasma membrane
2hn1A	[pdb]	1.27835 0.00266641	128^GLN 156^LEU 168^ASP 173^THR 176^ASP 181^SER	0.0.0.0	membrane	metal ion transmembrane transporter activity magnesium ion transmembrane transporter activity cobalt ion transmembrane transporter activity	metal ion transport magnesium ion transport cobalt ion transport
2c6uA	[pdb]	1.27885 0.00266648	107^ARG 129^TYR 136^THR 150^LYS 173^GLU 217^GLU	0.0.0.0	cell surface receptor linked signal transduction defense response	membrane integral to membrane integral to plasma membrane	sugar binding receptor activity transmembrane receptor activity binding
2g23D	[pdb]	1.27957 0.00266658	458^GLU 480^GLN 497^THR 500^ASP 520^SER 601^TYR			metal ion binding oxidoreductase activity copper ion binding	oxidation reduction antibiotic biosynthetic process
1xecB	[pdb]	1.28738 0.00280651	39^SER 58^ASP 75^LEU 80^THR 103^GLU 110^ASN		glycosaminoglycan binding extracellular matrix binding protein binding	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan	proteinaceous extracellular matrix extracellular region
1wraB	[pdb]	1.2922 0.00295359	58^ASP 109^THR 188^LEU 228^ASP 260^SER 302^ARG	0.0.0.0			hydrolase activity
3buuA	[pdb]	1.29471 0.00295398	142^ASP 149^ARG 162^GLU 164^THR 185^ARG 192^TYR	0.0.0.0
1gfsA	[pdb]	1.29554 0.00310874	185^LEU 204^SER 255^GLU 259^THR 283^LYS 302^GLU	1.1.1.271	cytoplasm	isomerase activity oxidoreductase activity catalytic activity GDP-L-fucose synthase activity coenzyme binding binding	oxidation reduction lipopolysaccharide biosynthetic process cellular metabolic process metabolic process
2ojkB	[pdb]	1.29878 0.00310928	17^ARG 70^ARG 169^LEU 205^THR 207^GLU 221^GLU				protein-chromophore linkage bioluminescence
2a7vA	[pdb]	1.29954 0.0031094	56^GLU 343^ARG 381^GLU 390^THR 418^ARG 469^LEU	2.1.2.1	glycine hydroxymethyltransferase activity transferase activity methyltransferase activity pyridoxal phosphate binding catalytic activity protein binding	mitochondrion mitochondrial matrix mitochondrial inner membrane mitochondrial nucleoid	one-carbon metabolic process L-serine metabolic process glycine metabolic process
2j04C	[pdb]	1.29995 0.00310947	26^ASP 53^LYS 339^SER 580^THR 584^ARG 586^LEU		DNA binding RNA polymerase III transcription factor activity DNA binding RNA polymerase III transcription factor activity	nucleus transcription factor TFIIIC complex nucleus transcription factor TFIIIC complex	regulation of transcription regulation of transcription regulation of transcription DNA-dependent transcription transcription initiation from RNA polymerase III promoter regulation of transcription DNA-dependent transcription transcription initiation from RNA polymerase III promoter
1j0kA	[pdb]	1.30573 0.00327412	25^LEU 62^THR 69^ASP 376^ASN 505^ARG 507^GLU	3.2.1.135		metabolic process carbohydrate metabolic process	metal ion binding hydrolase activity acting on glycosyl bonds hydrolase activity calcium ion binding neopullulanase activity cation binding hydrolase activity hydrolyzing O-glycosyl compounds catalytic activity
2e5sA	[pdb]	1.30736 0.0032744	21^GLU 30^ASN 39^ARG 50^ASP 55^THR 74^TYR			cytoplasm nucleus	metal ion binding zinc ion binding RNA binding nucleic acid binding
3equB	[pdb]	1.31075 0.00344848	271^ARG 322^ASP 430^GLN 441^ASP 466^THR 473^LEU		catalytic activity penicillin binding	cell division response to antibiotic peptidoglycan biosynthetic process regulation of cell shape cell cycle cell wall organization peptidoglycan-based cell wall biogenesis	plasma membrane membrane
1hn0A	[pdb]	1.31117 0.00344856	671^GLN 757^SER 817^ASP 830^THR 874^GLU 899^LEU	4.2.2.20	carbohydrate metabolic process	extracellular region	metal ion binding sodium ion binding lyase activity calcium ion binding chondroitin-sulfate-ABC endolyase activity carbohydrate binding carbon-oxygen lyase activity acting on polysaccharides catalytic activity
2am1A	[pdb]	1.31289 0.00344888	4^THR 19^SER 23^ASP 27^GLU 74^ASN 90^LEU	0.0.0.0	cell division peptidoglycan-based cell wall biogenesis peptidoglycan biosynthetic process biosynthetic process regulation of cell shape cell wall organization cell cycle	cytoplasm	ligase activity UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity ATP binding nucleotide binding
2czcB	[pdb]	1.31411 0.0034491	150^LEU 239^GLU 242^THR 258^GLN 275^GLU 300^SER	1.2.1.59	cytoplasm	oxidation reduction glycolysis metabolic process glucose metabolic process	oxidoreductase activity glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity NAD or NADH binding NADP or NADPH binding glyceraldehyde-3-phosphate dehydrogenase activity binding glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) activity catalytic activity
3c3wA	[pdb]	1.31548 0.00344936	35^SER 54^ASP 82^THR 101^TYR 167^ASN 195^GLU	0.0.0.0	DNA binding sequence-specific DNA binding transcription factor activity two-component response regulator activity	intracellular	transcription regulation of transcription DNA-dependent two-component signal transduction system (phosphorelay) regulation of transcription
1ddkA	[pdb]	1.31952 0.00363422	8^LYS 81^ASP 83^THR 87^GLU 97^TYR 196^SER	0.0.0.0		antibiotic catabolic process antibiotic catabolic process	hydrolase activity beta-lactamase activity zinc ion binding hydrolase activity beta-lactamase activity zinc ion binding
1rcqA	[pdb]	1.32007 0.00363433	160^SER 163^ASP 201^LYS 213^LEU 217^THR 227^ASP	5.1.1.1		alanine metabolic process peptidoglycan biosynthetic process	isomerase activity alanine racemase activity catalytic activity pyridoxal phosphate binding
1sv2B	[pdb]	1.32123 0.00363456	6^LEU 36^ASP 40^THR 45^GLU 70^ARG 137^LYS	3.5.1.88		metal ion binding hydrolase activity iron ion binding peptide deformylase activity	translation
2z63A	[pdb]	1.32168 0.00363464	241^ASN 264^ARG 294^ASP 319^THR 321^GLU 337^LEU		external side of plasma membrane integral to plasma membrane perinuclear region of cytoplasm lipopolysaccharide receptor complex membrane integral to membrane plasma membrane intrinsic to membrane	lipopolysaccharide receptor activity lipopolysaccharide binding transmembrane receptor activity receptor activity protein binding receptor activity protein binding	positive regulation of platelet activation response to lipopolysaccharide detection of lipopolysaccharide defense response to Gram-negative bacterium positive regulation of interleukin-8 biosynthetic process positive regulation of tumor necrosis factor biosynthetic process positive regulation of interleukin-12 biosynthetic process detection of fungus macrophage activation negative regulation of osteoclast differentiation T-helper 1 type immune response innate immune response immune response inflammatory response I-kappaB kinase/NF-kappaB cascade signal transduction positive regulation of JNK cascade positive regulation of I-kappaB kinase/NF-kappaB cascade positive regulation of tumor necrosis factor production response to bacterium production of nitric oxide during acute inflammatory response
2a85A	[pdb]	1.32257 0.00363482	13^LYS 75^LEU 317^ARG 324^GLU 327^THR 332^ASP	1.1.99.31	membrane peroxisome	oxidation reduction aromatic compound catabolic process mandelate metabolic process metabolic process oxidation reduction oxidative photosynthetic carbon pathway photorespiration metabolic process	oxidoreductase activity (S)-mandelate dehydrogenase activity FMN binding electron carrier activity catalytic activity oxidoreductase activity (S)-2-hydroxy-acid oxidase activity FMN binding electron carrier activity catalytic activity
2zhcA	[pdb]	1.32626 0.00383106	170^ASP 175^THR 194^ASP 201^LEU 291^LYS 307^SER				plasmid partitioning
2p3pB	[pdb]	1.32738 0.00383129	89^ARG 130^SER 134^GLU 153^THR 165^ASP 216^LEU	0.0.0.0
1wppB	[pdb]	1.32775 0.00383137	15^ASP 45^GLU 47^THR 53^TYR 123^SER 156^LYS	3.6.1.1		cytoplasm	metal ion binding manganese ion binding hydrolase activity pyrophosphatase activity inorganic diphosphatase activity
2rjqA	[pdb]	1.33333 0.00404025	290^TYR 485^GLU 490^THR 492^ASP 506^SER 516^ARG	0.0.0.0	metal ion binding hydrolase activity zinc ion binding metallopeptidase activity peptidase activity integrin binding metalloendopeptidase activity	plasma membrane cytoplasm nucleus proteinaceous extracellular matrix extracellular region extracellular matrix	proteolysis
2yz2A	[pdb]	1.33548 0.00404073	34^GLU 70^ARG 78^ARG 158^ASP 190^THR 193^LEU		hydrolase activity ATP binding nucleotide binding nucleoside-triphosphatase activity ATPase activity	plasma membrane membrane	transport
1iwpA	[pdb]	1.33696 0.00404106	138^ARG 289^LYS 333^SER 359^ASP 509^LEU 521^ASP	0.0.0.0		lyase activity glycerol dehydratase activity lyase activity glycerol dehydratase activity cobalamin binding hydro-lyase activity catalytic activity lyase activity glycerol dehydratase activity	metabolic process
3d2qD	[pdb]	1.34056 0.00426252	183^GLU 192^ASN 201^ARG 212^ASP 217^THR 236^TYR	0.0.0.0	cytoplasm nucleus	double-stranded RNA binding metal ion binding zinc ion binding RNA binding nucleic acid binding	nervous system development myoblast differentiation muscle organ development embryonic limb morphogenesis in utero embryonic development
1oyjC	[pdb]	1.34115 0.00426266	110^TYR 139^GLU 143^THR 145^GLU 151^ARG 199^ARG	2.5.1.18			transferase activity glutathione transferase activity transferase activity glutathione transferase activity
1nktB	[pdb]	1.34544 0.00449794	431^GLN 468^GLU 492^THR 493^ASP 503^LEU 573^ARG		ATP binding nucleotide binding protein binding	intracellular protein transmembrane transport protein transport transport protein import intracellular protein transport protein targeting	plasma membrane cytoplasm membrane
1u79B	[pdb]	1.34631 0.00449815	14^LEU 18^ASP 34^LYS 49^SER 90^THR 122^ASP	5.2.1.8	chloroplast thylakoid lumen plastid chloroplast thylakoid lumen thylakoid	peptidyl-prolyl cis-trans isomerase activity isomerase activity	protein folding
1ud9A	[pdb]	1.34623 0.00449813	30^LYS 77^LEU 86^GLU 90^ASP 93^SER 100^THR		DNA binding DNA polymerase processivity factor activity	DNA replication regulation of DNA replication	PCNA complex
3f4lD	[pdb]	1.34629 0.00449815	154^ASP 173^TYR 196^ASP 209^THR 220^LYS 339^SER			oxidation reduction metabolic process	oxidoreductase activity electron carrier activity binding catalytic activity protein binding
1ka9F	[pdb]	1.34688 0.00449829	105^SER 131^ASP 160^LYS 172^THR 184^ASP 223^LEU		cellular amino acid biosynthetic process histidine biosynthetic process metabolic process cellular amino acid biosynthetic process glutamine metabolic process histidine biosynthetic process	cytoplasm imidazoleglycerol-phosphate synthase complex cytoplasm	protein binding imidazoleglycerol-phosphate synthase activity lyase activity catalytic activity imidazoleglycerol-phosphate synthase activity transferase activity transferase activity transferring pentosyl groups catalytic activity protein binding
1mppA	[pdb]	1.34769 0.00449849	37^ASP 54^ARG 61^SER 69^TYR 87^ASP 100^THR	3.4.23.23		hydrolase activity peptidase activity aspartic-type endopeptidase activity	proteolysis
1vgvC	[pdb]	1.35071 0.00449922	117^GLU 135^ARG 154^GLN 172^THR 358^ASP 366^LEU	5.1.3.14	cytoplasm	entry of virus into host cell detection of virus lipopolysaccharide biosynthetic process UDP-N-acetylglucosamine metabolic process	isomerase activity UDP-N-acetylglucosamine 2-epimerase activity
1md9A	[pdb]	1.35149 0.00474071	190^SER 209^TYR 309^LYS 334^GLU 361^ASP 388^THR		cytoplasm	ligase activity ATP binding nucleotide binding (2,3-dihydroxybenzoyl)adenylate synthase activity catalytic activity	metabolic process siderophore biosynthetic process
1jymB	[pdb]	1.3533 0.00474117	66^LYS 77^ARG 80^GLU 82^THR 85^ASP 174^TYR	0.0.0.0		hydrolase activity formylmethionine deformylase activity peptide deformylase activity iron ion binding	translation
1qjqA	[pdb]	1.35729 0.00474217	72^TYR 167^LYS 630^ASP 645^THR 670^ASP 715^ARG		cell outer membrane integral to membrane membrane plasma membrane	entry of virus into host cell detection of virus iron ion transport ion transport transport siderophore transport	iron ion binding receptor activity siderophore-iron transmembrane transporter activity transporter activity
2w4mA	[pdb]	1.35762 0.00474225	16^THR 19^ASP 53^GLN 104^ARG 130^LEU 189^ASP	3.1.3.29	N-acetylneuraminate biosynthetic process carbohydrate metabolic process metabolic process	N-acylneuraminate-9-phosphatase activity hydrolase activity phosphoglycolate phosphatase activity catalytic activity magnesium ion binding	cellular_component
1ia6A	[pdb]	1.35834 0.00474243	67^GLN 208^SER 253^THR 258^ASP 265^LEU 313^GLU	0.0.0.0		carbohydrate metabolic process polysaccharide catabolic process	hydrolase activity hydrolyzing O-glycosyl compounds catalytic activity
1k9tA	[pdb]	1.35953 0.00499141	187^LEU 225^LYS 278^SER 313^ASP 358^GLU 360^THR	3.2.1.14		cation binding chitinase activity hydrolase activity hydrolyzing O-glycosyl compounds catalytic activity hydrolase activity acting on glycosyl bonds hydrolase activity chitinase activity cation binding hydrolase activity hydrolyzing O-glycosyl compounds catalytic activity hydrolase activity hydrolase activity acting on glycosyl bonds	chitin catabolic process carbohydrate metabolic process metabolic process chitin catabolic process carbohydrate metabolic process polysaccharide catabolic process metabolic process
1pm2B	[pdb]	1.35957 0.00499142	44^LEU 89^ARG 103^GLU 106^THR 109^GLU 201^ASN	1.17.4.1	cytosol	metal ion binding oxidoreductase activity ribonucleoside-diphosphate reductase activity transition metal ion binding protein binding iron ion binding	oxidation reduction DNA replication deoxyribonucleoside diphosphate metabolic process
1bjnB	[pdb]	1.36384 0.00499256	122^LYS 160^ASP 162^THR 164^ASP 189^TYR 296^SER	2.6.1.52	cellular amino acid biosynthetic process pyridoxine biosynthetic process L-serine biosynthetic process metabolic process	cytoplasm	transferase activity transaminase activity O-phospho-L-serine:2-oxoglutarate aminotransferase activity pyridoxal phosphate binding catalytic activity protein binding
2nn6C	[pdb]	1.36654 0.00525689	90^VAL 103^ILE 145^THR 209^PRO 211^HIS 217^ILE		exosome (RNase complex) nucleolus nucleus nucleolus cytoplasm nucleus exosome (RNase complex) cytoplasm nucleus exosome (RNase complex) cellular_component cytoplasm nucleus exosome (RNase complex) nucleolus nucleolus nucleolus nucleolus nucleolus exosome (RNase complex) nucleus cytoplasm nucleolus nucleus exosome (RNase complex) nuclear exosome (RNase complex) cytoplasm nucleus exosome (RNase complex) nucleolus cytoplasmic exosome (RNase complex) nuclear exosome (RNase complex) cytoplasm nucleus exosome (RNase complex) cytoplasm nucleus exosome (RNase complex)	protein binding RNA binding hydrolase activity exonuclease activity nuclease activity protein binding 3'-5'-exoribonuclease activity hydrolase activity exonuclease activity nuclease activity RNA binding hydrolase activity exonuclease activity nuclease activity RNA binding 7S RNA binding 3'-5'-exoribonuclease activity protein binding molecular_function hydrolase activity exonuclease activity nuclease activity RNA binding 3'-5'-exoribonuclease activity identical protein binding protein binding protein binding RNA binding 3'-5'-exoribonuclease activity hydrolase activity exonuclease activity nuclease activity 3'-5'-exoribonuclease activity hydrolase activity exonuclease activity nuclease activity RNA binding protein binding RNA binding 3'-5'-exoribonuclease activity hydrolase activity exonuclease activity nuclease activity protein binding 3'-5'-exoribonuclease activity hydrolase activity exonuclease activity nuclease activity RNA binding protein binding hydrolase activity exonuclease activity nuclease activity RNA binding 3'-5'-exoribonuclease activity	rRNA processing rRNA processing RNA processing rRNA processing biological_process rRNA processing RNA processing RNA catabolic process rRNA processing RNA processing rRNA processing RNA processing immune response rRNA processing RNA processing rRNA processing rRNA processing RNA processing
1vqvB	[pdb]	1.36688 0.00525698	157^LEU 203^ASN 278^ASP 280^THR 281^GLU 284^ARG	0.0.0.0		kinase activity thiamin phosphate kinase activity catalytic activity	thiamin biosynthetic process

PDB ID

LRMSD /
p-value

Matching Residues

Gene Ontology annotations

Biological Process

Cellular Component

Molecular Function

1adjB

[pdb]

0.135874
2.23026e-05

81^GLU 83^THR 112^ARG 130^GLU 264^TYR 311^ARG

6.1.1.21

cytoplasm

ligase activity
ATP binding
aminoacyl-tRNA ligase activity
nucleotide binding
histidine-tRNA ligase activity

translation
histidyl-tRNA aminoacylation
tRNA aminoacylation for protein translation

1httD

[pdb]

0.361492
6.85666e-05

83^GLU 85^THR 113^ARG 131^GLU 264^TYR 311^ARG

6.1.1.21

ATP binding
histidine-tRNA ligase activity
ligase activity
aminoacyl-tRNA ligase activity
nucleotide binding
ligase activity
ATP binding
aminoacyl-tRNA ligase activity
nucleotide binding
histidine-tRNA ligase activity
ligase activity
ATP binding
aminoacyl-tRNA ligase activity
nucleotide binding
histidine-tRNA ligase activity

cytoplasm
cytoplasm
cytoplasm

histidyl-tRNA aminoacylation
translation
tRNA aminoacylation for protein translation
translation
histidyl-tRNA aminoacylation
tRNA aminoacylation for protein translation
translation
histidyl-tRNA aminoacylation
tRNA aminoacylation for protein translation

2q09A

[pdb]

0.898837
0.000135665

38^ARG 57^GLN 133^GLU 136^THR 165^LEU 374^ASP

cytoplasm

histidine metabolic process
histidine catabolic process to glutamate and formamide
histidine catabolic process

metal ion binding
hydrolase activity
zinc ion binding
iron ion binding
imidazolonepropionase activity
hydrolase activity
acting on carbon-nitrogen (but not peptide) bonds
in cyclic amides
hydrolase activity
acting on carbon-nitrogen (but not peptide) bonds

2oogB

[pdb]

0.906773
0.000144909

60^ARG 89^ASP 159^ARG 170^THR 180^GLU 225^LEU

glycerophosphodiester phosphodiesterase activity
phosphoric diester hydrolase activity
glycerophosphodiester phosphodiesterase activity
phosphoric diester hydrolase activity

lipid metabolic process
glycerol metabolic process
lipid metabolic process
glycerol metabolic process

2pt3A

[pdb]

1.03429
0.000300749

269^LEU 360^ARG 393^ASP 555^ASP 557^THR 570^ASN

1.11.1.7

extracellular region
extracellular space

metal ion binding
oxidoreductase activity
calcium ion binding
iron ion binding
peroxidase activity
heme binding

oxidation reduction
hydrogen peroxide catabolic process
defense response to bacterium
response to oxidative stress

3db9A

[pdb]

1.05143
0.000339961

24^ARG 72^ASP 77^THR 80^LEU 85^ASP 94^ARG

2yvdD

[pdb]

1.06482
0.00038837

67^ARG 145^SER 162^ASP 188^THR 341^TYR 402^GLU

cytoplasm

metal ion binding
hydrolase activity
zinc ion binding
endonuclease activity
nuclease activity
RNA binding

rRNA processing

1wf4e

[pdb]

1.06975
0.000416411

36^ALA 76^GLY 81^GLU 87^TYR 151^SER 506^LEU

0.0.0.0

ATP binding
ATP binding
nucleotide binding
protein binding
unfolded protein binding

cytoplasm
cytoplasm

protein folding
protein folding
cellular protein metabolic process
protein refolding

2zyqA

[pdb]

1.08526
0.00048124

8^TYR 138^THR 140^GLU 219^GLU 249^ASN 254^SER

0.0.0.0

oxidation reduction
cellular aromatic compound metabolic process
aromatic compound catabolic process

oxidoreductase activity
acting on single donors with incorporation of molecular oxygen
incorporation of two atoms of oxygen
oxidoreductase activity
biphenyl-2,3-diol 1,2-dioxygenase activity
ferrous iron binding
catalytic activity
iron ion binding

1yz6A

[pdb]

1.09143
0.000518181

201^ARG 211^ASP 225^ARG 227^ASP 229^THR 234^TYR

eukaryotic translation initiation factor 2 complex

translation
translational initiation

translation initiation factor activity
RNA binding

3d8bA

[pdb]

1.10162
0.00055852

464^SER 500^ASP 527^GLN 545^THR 550^GLU 563^LEU

ATP metabolic process

hydrolase activity
magnesium ion binding
metal ion binding
ATP binding
nucleotide binding
nucleoside-triphosphatase activity

3f0eA

[pdb]

1.11598
0.000649116

80^ARG 97^ASP 99^THR 107^LEU 128^ARG 149^GLU

4.6.1.12

isoprenoid biosynthetic process
terpenoid biosynthetic process

metal ion binding
lyase activity
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity

1uzgB

[pdb]

1.11678
0.000649156

120^GLN 126^GLU 198^THR 201^ASP 220^SER 262^LEU

3.4.21.91, 2.7.7.48, 2.1.1.56

hydrolase activity
nucleotidyltransferase activity
transferase activity
ATP binding
structural molecule activity
helicase activity
RNA-directed RNA polymerase activity
nucleotide binding
mRNA (guanine-N7-)-methyltransferase activity
ATP-dependent helicase activity
serine-type endopeptidase activity
catalytic activity
double-stranded RNA binding
RNA helicase activity
RNA binding
nucleic acid binding
methyltransferase activity

membrane
viral envelope
viral capsid
viral nucleocapsid
virion
integral to membrane
virion part

transcription
RNA-dependent
viral genome replication
viral infectious cycle
RNA metabolic process
viral reproduction
methylation

1dbiA

[pdb]

1.12611
0.000751807

34^GLU 83^GLU 97^THR 103^ARG 126^SER 235^LEU

extracellular region

metal ion binding
hydrolase activity
serine-type peptidase activity
peptidase activity
calcium ion binding
serine-type endopeptidase activity

proteolysis

2pifA

[pdb]

1.12612
0.000751807

23^ARG 71^ASP 76^THR 79^LEU 84^ASP 93^ARG

1qe0A

[pdb]

1.13561
0.000806135

80^GLU 82^THR 112^ARG 130^GLU 262^TYR 312^ARG

6.1.1.21

cytoplasm

ligase activity
ATP binding
aminoacyl-tRNA ligase activity
nucleotide binding
histidine-tRNA ligase activity

translation
histidyl-tRNA aminoacylation
tRNA aminoacylation for protein translation

4pgaB

[pdb]

1.15275
0.000925808

68^GLU 75^LEU 102^THR 104^GLU 139^ASN 167^SER

3.5.1.38

asparagine metabolic process
cellular amino acid metabolic process

hydrolase activity
glutamin-(asparagin-)ase activity
asparaginase activity

periplasmic space

2v4wA

[pdb]

1.15585
0.000990867

273^TYR 291^THR 294^ASP 319^ASP 369^LYS 405^SER

2.3.3.10

mitochondrion
mitochondrial matrix
mitochondrial inner membrane

sterol biosynthetic process
lipid biosynthetic process
cholesterol biosynthetic process
steroid biosynthetic process
isoprenoid biosynthetic process
metabolic process
response to peptide hormone stimulus
response to drug
response to nutrient

transferase activity
hydroxymethylglutaryl-CoA synthase activity
catalytic activity

2jd4B

[pdb]

1.15912
0.000991093

2721^ARG 2758^LEU 2788^GLU 2797^THR 2799^ASP 2855^GLN

basement membrane
proteinaceous extracellular matrix
extracellular region
basal lamina
extracellular matrix
laminin-1 complex

cell adhesion
establishment of epithelial cell apical/basal polarity
tissue development
cell surface receptor linked signal transduction
morphogenesis of an epithelial sheet
regulation of embryonic development
regulation of cell migration
regulation of cell adhesion
branching involved in lung morphogenesis
branching involved in salivary gland morphogenesis

protein binding
extracellular matrix structural constituent
receptor binding

3pga4

[pdb]

1.16236
0.00105984

68^GLU 75^LEU 102^THR 104^GLU 139^ASN 167^SER

3.5.1.38

asparagine metabolic process
cellular amino acid metabolic process

hydrolase activity
glutamin-(asparagin-)ase activity
asparaginase activity

periplasmic space

1k5gI

[pdb]

1.16348
0.00105992

40^SER 66^GLU 91^LEU 98^THR 125^GLU 131^ASN

perinuclear region of cytoplasm
nuclear pore
chromatin
cytoplasm
melanosome
nucleus
cytosol
nucleoplasm
cytoplasm
nuclear membrane
cytosol
cytoplasm
nucleus
centrosome

positive regulation of transcription
DNA-dependent
androgen receptor signaling pathway
signal transduction
mitosis
mitotic spindle organization
protein export from nucleus
RNA export from nucleus
DNA metabolic process
interspecies interaction between organisms
protein transport
transport
nucleocytoplasmic transport
intracellular protein transport
kinetochore organization
Ran protein signal transduction
chromatin silencing at centromere
chromosome segregation
nucleocytoplasmic transport
chromatin silencing at telomere
signal transduction
intracellular transport
positive regulation of mitotic centrosome separation
spindle organization

protein binding
androgen receptor binding
transcription coactivator activity
GTPase activity
GTP binding
chromatin binding
nucleotide binding
Ran GTPase activator activity
GTPase activator activity
GTPase activator activity
Ran GTPase binding
GDP-dissociation inhibitor activity
protein binding

1pznB

[pdb]

1.1684
0.00113242

135^GLU 151^LEU 204^ARG 216^GLN 238^ASP 282^THR

ATP binding
DNA binding
nucleotide binding
sequence-specific DNA binding
nucleoside-triphosphatase activity
DNA-dependent ATPase activity
protein binding
damaged DNA binding

intracellular

response to DNA damage stimulus
DNA recombination
DNA repair
DNA metabolic process

1iq0A

[pdb]

1.16856
0.00113243

108^GLU 111^SER 136^LEU 333^ARG 347^GLU 349^THR

6.1.1.19

arginyl-tRNA aminoacylation
translation
tRNA aminoacylation for protein translation
translation
arginyl-tRNA aminoacylation
tRNA aminoacylation for protein translation

cytoplasm
cytoplasm

nucleotide binding
ATP binding
arginine-tRNA ligase activity
ligase activity
aminoacyl-tRNA ligase activity
ATP binding
arginine-tRNA ligase activity
aminoacyl-tRNA ligase activity
nucleotide binding
ligase activity

1abrA

[pdb]

1.17705
0.00120885

24^MET 53^LEU 63^ARG 65^ASN 69^LEU 153^SER

0.0.0.0

cellular_component

hydrolase activity
sugar binding
rRNA N-glycosylase activity
galactose binding

negative regulation of translation
pathogenesis
defense response
positive regulation of endocytosis

1wovA

[pdb]

1.17904
0.00120901

20^GLU 22^THR 138^LYS 210^GLU 225^LEU 233^SER

1.14.99.3

metal ion binding
oxidoreductase activity
iron ion binding
heme oxygenase (decyclizing) activity

oxidation reduction
photosynthesis
heme oxidation

2j22A

[pdb]

1.18311
0.00128869

24^GLN 88^SER 91^ASP 101^GLU 104^THR 119^LEU

0.0.0.0

cell adhesion

1d2vC

[pdb]

1.18446
0.00128881

254^LEU 345^ARG 378^ASP 539^ASP 541^THR 555^ASN

1.11.1.7

lysosome
nucleus
extracellular space

metal ion binding
oxidoreductase activity
calcium ion binding
iron ion binding
peroxidase activity
chromatin binding
heme binding

response to oxidative stress
oxidation reduction
hydrogen peroxide catabolic process
defense response
anti-apoptosis
low-density lipoprotein particle remodeling

1z7nB

[pdb]

1.1923
0.0013724

84^LEU 86^TYR 112^ARG 130^GLU 283^GLN 294^LEU

cellular amino acid biosynthetic process
histidine biosynthetic process
histidyl-tRNA aminoacylation
tRNA aminoacylation for protein translation
translation
cellular amino acid biosynthetic process
histidine biosynthetic process

cytoplasm
cytoplasm

nucleotide binding
ATP binding
ATP binding
histidine-tRNA ligase activity
aminoacyl-tRNA ligase activity
nucleotide binding
transferase activity
transferring glycosyl groups
transferase activity
ATP phosphoribosyltransferase activity

1reqC

[pdb]

1.19785
0.00145938

129^LEU 513^VAL 516^ALA 532^SER 553^ILE 558^LYS

5.4.99.2

cobalt ion binding
cobalamin binding
isomerase activity
methylmalonyl-CoA mutase activity
metal ion binding
intramolecular transferase activity
catalytic activity
cobalt ion binding
metal ion binding
cobalamin binding
isomerase activity
methylmalonyl-CoA mutase activity
intramolecular transferase activity
catalytic activity

lactate fermentation to propionate and acetate
metabolic process
metabolic process

2isaB

[pdb]

1.20135
0.0014597

65^THR 81^ASP 116^TYR 217^SER 261^GLN 294^GLU

0.0.0.0

oxidation reduction
response to oxidative stress
hydrogen peroxide catabolic process

oxidoreductase activity
peroxidase activity
catalase activity
heme binding
iron ion binding
metal ion binding

2f8sA

[pdb]

1.20563
0.00155014

103^ASP 106^THR 112^ASP 116^SER 160^LYS 298^LEU

0.0.0.0

nucleic acid binding

1m9nB

[pdb]

1.20634
0.0015502

438^LYS 461^ASP 493^ASP 497^THR 520^LEU 551^ARG

3.5.4.10, 2.1.2.3

hydrolase activity
transferase activity
catalytic activity
phosphoribosylaminoimidazolecarboxamide formyltransferase activity
IMP cyclohydrolase activity

purine nucleotide biosynthetic process
IMP biosynthetic process

2jizE

[pdb]

1.21049
0.00164423

59^ARG 119^GLU 237^LYS 266^ILE 288^ASP 291^THR

3.6.3.14

ATP catabolic process
proton transport
ion transport
transport
ATP biosynthetic process
ATP metabolic process
ATP synthesis coupled proton transport
lipid metabolic process
negative regulation of cell adhesion involved in substrate-bound cell migration
lipid metabolic process
embryonic development
ATP metabolic process
proton transport
ATP synthesis coupled proton transport
ion transport
transport
ATP biosynthetic process
proton transport
ion transport
transport
ATP biosynthetic process
ATP synthesis coupled proton transport

mitochondrial inner membrane
mitochondrion
proton-transporting ATP synthase complex
catalytic core F(1)
membrane
proton-transporting two-sector ATPase complex
catalytic domain
proton-transporting two-sector ATPase complex
mitochondrion
proton-transporting ATP synthase complex
catalytic core F(1)
proton-transporting two-sector ATPase complex
catalytic domain
proton-transporting two-sector ATPase complex
mitochondrial inner membrane
membrane
mitochondrial inner membrane
mitochondrion
proton-transporting ATP synthase complex
catalytic core F(1)
membrane

protein binding
metal ion binding
hydrolase activity
hydrogen ion transmembrane transporter activity
ATP binding
proton-transporting ATPase activity
rotational mechanism
hydrogen ion transporting ATP synthase activity
rotational mechanism
nucleoside-triphosphatase activity
hydrolase activity
acting on acid anhydrides
catalyzing transmembrane movement of substances
hydrogen-exporting ATPase activity
phosphorylative mechanism
nucleotide binding
ATP binding
nucleotide binding
proton-transporting ATPase activity
rotational mechanism
hydrogen ion transporting ATP synthase activity
rotational mechanism
hydrolase activity
acting on acid anhydrides
catalyzing transmembrane movement of substances
protein binding
metal ion binding
hydrogen ion transmembrane transporter activity
protein binding
metal ion binding
hydrogen ion transmembrane transporter activity
proton-transporting ATPase activity
rotational mechanism
hydrogen ion transporting ATP synthase activity
rotational mechanism

3cpgA

[pdb]

1.2109
0.00164427

24^GLU 26^THR 33^LEU 69^ASP 86^LYS 97^ARG

0.0.0.0

1w27A

[pdb]

1.21119
0.0016443

136^ARG 161^LEU 197^ARG 205^ASP 262^THR 383^ASP

4.3.1.24

cytoplasm

lyase activity
ammonia-lyase activity
ammonia ligase activity
catalytic activity

phenylpropanoid metabolic process
biosynthetic process
L-phenylalanine catabolic process

2eryA

[pdb]

1.21171
0.00164435

67^LEU 80^GLU 85^THR 87^GLU 150^LYS 176^ARG

GTP binding
nucleotide binding
GTPase activity
protein binding

plasma membrane
membrane
endoplasmic reticulum
intracellular

small GTPase mediated signal transduction
positive regulation of cell migration
cellular process
Ras protein signal transduction

3chjA

[pdb]

1.214
0.00164458

82^ARG 91^ARG 113^THR 115^GLU 156^ASP 240^LEU

0.0.0.0

calcium-dependent phospholipid binding
calcium ion binding
calcium-dependent phospholipid binding
calcium ion binding

cell projection
flagellum
cilium

cell projection organization

3gf8A

[pdb]

1.21569
0.00164474

63^TYR 109^SER 111^ASP 113^THR 124^ASP 237^ARG

0.0.0.0

1n35A

[pdb]

1.21944
0.00174247

696^SER 700^GLU 704^THR 709^GLU 719^LEU 770^LYS

2.7.7.48

hydrolase activity
nucleotidyltransferase activity
transferase activity
structural molecule activity
RNA-directed RNA polymerase activity
nucleotide binding
RNA binding

transcription
RNA-dependent
RNA biosynthetic process
viral genome replication

virion
viral capsid
viral nucleocapsid

1qycA

[pdb]

1.22105
0.00174263

134^LYS 217^LEU 267^SER 275^ASP 277^THR 280^GLU

0.0.0.0

metabolic process
regulation of nitrogen utilization

transcription repressor activity
binding
catalytic activity

1ug9A

[pdb]

1.22156
0.00174268

41^THR 57^GLU 71^GLU 117^LEU 138^SER 182^ASN

0.0.0.0

carbohydrate catabolic process
polysaccharide metabolic process
carbohydrate metabolic process

catalytic activity
carbohydrate binding
hydrolase activity
hydrolyzing O-glycosyl compounds
glucan 1,4-alpha-glucosidase activity

1kmyA

[pdb]

1.22227
0.00174276

8^TYR 139^THR 141^GLU 214^GLU 243^ASN 248^SER

1.13.11.39

metal ion binding
oxidoreductase activity
acting on single donors with incorporation of molecular oxygen
incorporation of two atoms of oxygen
oxidoreductase activity
iron ion binding
biphenyl-2,3-diol 1,2-dioxygenase activity
dioxygenase activity
ferrous iron binding
catalytic activity

oxidation reduction
aromatic compound catabolic process
xenobiotic catabolic process
cellular aromatic compound metabolic process

1gw7K

[pdb]

1.22695
0.00184451

2018^GLN 2028^ARG 2253^ASP 2256^THR 2379^TYR 2385^GLU

0.0.0.0

structural molecule activity

virion
viral capsid

3exg1

[pdb]

1.22711
0.00184453

37^TYR 76^PRO 98^ALA 235^VAL 237^ASN 255^LYS

0.0.0.0

mitochondrial matrix
mitochondrion
intracellular membrane-bounded organelle
mitochondrial matrix
mitochondrion

oxidation reduction
glycolysis
oxidation reduction
glycolysis
tricarboxylic acid cycle
metabolic process
metabolic process

oxidoreductase activity
pyruvate dehydrogenase (acetyl-transferring) activity
oxidoreductase activity
acting on the aldehyde or oxo group of donors
disulfide as acceptor
pyruvate dehydrogenase activity
oxidoreductase activity
pyruvate dehydrogenase (acetyl-transferring) activity
catalytic activity
protein binding

2r5eB

[pdb]

1.23251
0.00195057

190^THR 195^LEU 200^ASP 222^GLU 252^SER 315^ASN

0.0.0.0

biosynthetic process

transferase activity
transaminase activity
pyridoxal phosphate binding
1-aminocyclopropane-1-carboxylate synthase activity
transferase activity
transferring nitrogenous groups
catalytic activity

2azkB

[pdb]

1.26109
0.00240645

110^ASN 126^ASP 131^THR 134^GLU 140^SER 171^LEU

0.0.0.0

isoprenoid biosynthetic process

transferase activity
geranyltranstransferase activity
farnesyltranstransferase activity
dimethylallyltranstransferase activity

3fe1B

[pdb]

1.26117
0.00240646

17^TYR 206^THR 208^ASP 210^SER 234^ASP 353^GLN

ATP binding
nucleotide binding

response to stress
response to unfolded protein

1pbkA

[pdb]

1.2623
0.00240661

110^LYS 114^SER 136^THR 146^ASP 162^LEU 217^GLU

5.2.1.8

cytoplasm
nucleus

isomerase activity
peptidyl-prolyl cis-trans isomerase activity
FK506 binding
receptor activity

protein folding

1vkhA

[pdb]

1.26292
0.00240668

44^GLU 46^THR 72^GLU 81^ASN 90^SER 247^TYR

3.5.1.9

hydrolase activity
arylformamidase activity

tryptophan catabolic process
NAD biosynthetic process

2b6nA

[pdb]

1.26709
0.00253295

14^ASP 16^ARG 26^THR 29^ASP 82^TYR 253^LYS

0.0.0.0

identical protein binding
peptidase activity
serine-type endopeptidase activity
serine-type peptidase activity
hydrolase activity
identical protein binding
peptidase activity
serine-type endopeptidase activity

negative regulation of catalytic activity
proteolysis
negative regulation of catalytic activity
proteolysis

2h0bA

[pdb]

1.26737
0.00253299

299^ASN 305^SER 307^GLU 309^THR 333^LEU 447^GLU

cell adhesion

membrane
integral to membrane

metal ion binding
protein binding
calcium ion binding

1fj7A

[pdb]

1.27292
0.00253372

5^LEU 13^GLU 15^THR 39^SER 51^ASP 58^ARG

nucleolus
nucleus

telomeric DNA binding
RNA binding
DNA binding
nucleic acid binding
nucleotide binding

1a4qA

[pdb]

1.27425
0.00266584

226^SER 254^LYS 271^GLU 273^THR 275^GLU 315^LEU

3.2.1.18

hydrolase activity
acting on glycosyl bonds
hydrolase activity
exo-alpha-sialidase activity

metabolic process
carbohydrate metabolic process

virion membrane
apical plasma membrane
virion
integral to membrane
membrane
plasma membrane

2hn1A

[pdb]

1.27835
0.00266641

128^GLN 156^LEU 168^ASP 173^THR 176^ASP 181^SER

0.0.0.0

membrane

metal ion transmembrane transporter activity
magnesium ion transmembrane transporter activity
cobalt ion transmembrane transporter activity

metal ion transport
magnesium ion transport
cobalt ion transport

2c6uA

[pdb]

1.27885
0.00266648

107^ARG 129^TYR 136^THR 150^LYS 173^GLU 217^GLU

0.0.0.0

cell surface receptor linked signal transduction
defense response

membrane
integral to membrane
integral to plasma membrane

sugar binding
receptor activity
transmembrane receptor activity
binding

2g23D

[pdb]

1.27957
0.00266658

458^GLU 480^GLN 497^THR 500^ASP 520^SER 601^TYR

metal ion binding
oxidoreductase activity
copper ion binding

oxidation reduction
antibiotic biosynthetic process

1xecB

[pdb]

1.28738
0.00280651

39^SER 58^ASP 75^LEU 80^THR 103^GLU 110^ASN

glycosaminoglycan binding
extracellular matrix binding
protein binding

peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan

proteinaceous extracellular matrix
extracellular region

1wraB

[pdb]

1.2922
0.00295359

58^ASP 109^THR 188^LEU 228^ASP 260^SER 302^ARG

0.0.0.0

hydrolase activity

3buuA

[pdb]

1.29471
0.00295398

142^ASP 149^ARG 162^GLU 164^THR 185^ARG 192^TYR

0.0.0.0

1gfsA

[pdb]

1.29554
0.00310874

185^LEU 204^SER 255^GLU 259^THR 283^LYS 302^GLU

1.1.1.271

cytoplasm

isomerase activity
oxidoreductase activity
catalytic activity
GDP-L-fucose synthase activity
coenzyme binding
binding

oxidation reduction
lipopolysaccharide biosynthetic process
cellular metabolic process
metabolic process

2ojkB

[pdb]

1.29878
0.00310928

17^ARG 70^ARG 169^LEU 205^THR 207^GLU 221^GLU

protein-chromophore linkage
bioluminescence

2a7vA

[pdb]

1.29954
0.0031094

56^GLU 343^ARG 381^GLU 390^THR 418^ARG 469^LEU

2.1.2.1

glycine hydroxymethyltransferase activity
transferase activity
methyltransferase activity
pyridoxal phosphate binding
catalytic activity
protein binding

mitochondrion
mitochondrial matrix
mitochondrial inner membrane
mitochondrial nucleoid

one-carbon metabolic process
L-serine metabolic process
glycine metabolic process

2j04C

[pdb]

1.29995
0.00310947

26^ASP 53^LYS 339^SER 580^THR 584^ARG 586^LEU

DNA binding
RNA polymerase III transcription factor activity
DNA binding
RNA polymerase III transcription factor activity

nucleus
transcription factor TFIIIC complex
nucleus
transcription factor TFIIIC complex

regulation of transcription
regulation of transcription
regulation of transcription
DNA-dependent
transcription
transcription initiation from RNA polymerase III promoter
regulation of transcription
DNA-dependent
transcription
transcription initiation from RNA polymerase III promoter

1j0kA

[pdb]

1.30573
0.00327412

25^LEU 62^THR 69^ASP 376^ASN 505^ARG 507^GLU

3.2.1.135

metabolic process
carbohydrate metabolic process

metal ion binding
hydrolase activity
acting on glycosyl bonds
hydrolase activity
calcium ion binding
neopullulanase activity
cation binding
hydrolase activity
hydrolyzing O-glycosyl compounds
catalytic activity

2e5sA

[pdb]

1.30736
0.0032744

21^GLU 30^ASN 39^ARG 50^ASP 55^THR 74^TYR

cytoplasm
nucleus

metal ion binding
zinc ion binding
RNA binding
nucleic acid binding

3equB

[pdb]

1.31075
0.00344848

271^ARG 322^ASP 430^GLN 441^ASP 466^THR 473^LEU

catalytic activity
penicillin binding

cell division
response to antibiotic
peptidoglycan biosynthetic process
regulation of cell shape
cell cycle
cell wall organization
peptidoglycan-based cell wall biogenesis

plasma membrane
membrane

1hn0A

[pdb]

1.31117
0.00344856

671^GLN 757^SER 817^ASP 830^THR 874^GLU 899^LEU

4.2.2.20

carbohydrate metabolic process

extracellular region

metal ion binding
sodium ion binding
lyase activity
calcium ion binding
chondroitin-sulfate-ABC endolyase activity
carbohydrate binding
carbon-oxygen lyase activity
acting on polysaccharides
catalytic activity

2am1A

[pdb]

1.31289
0.00344888

4^THR 19^SER 23^ASP 27^GLU 74^ASN 90^LEU

0.0.0.0

cell division
peptidoglycan-based cell wall biogenesis
peptidoglycan biosynthetic process
biosynthetic process
regulation of cell shape
cell wall organization
cell cycle

cytoplasm

ligase activity
UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity
ATP binding
nucleotide binding

2czcB

[pdb]

1.31411
0.0034491

150^LEU 239^GLU 242^THR 258^GLN 275^GLU 300^SER

1.2.1.59

cytoplasm

oxidation reduction
glycolysis
metabolic process
glucose metabolic process

oxidoreductase activity
glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity
NAD or NADH binding
NADP or NADPH binding
glyceraldehyde-3-phosphate dehydrogenase activity
binding
glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) activity
catalytic activity

3c3wA

[pdb]

1.31548
0.00344936

35^SER 54^ASP 82^THR 101^TYR 167^ASN 195^GLU

0.0.0.0

DNA binding
sequence-specific DNA binding
transcription factor activity
two-component response regulator activity

intracellular

transcription
regulation of transcription
DNA-dependent
two-component signal transduction system (phosphorelay)
regulation of transcription

1ddkA

[pdb]

1.31952
0.00363422

8^LYS 81^ASP 83^THR 87^GLU 97^TYR 196^SER

0.0.0.0

antibiotic catabolic process
antibiotic catabolic process

hydrolase activity
beta-lactamase activity
zinc ion binding
hydrolase activity
beta-lactamase activity
zinc ion binding

1rcqA

[pdb]

1.32007
0.00363433

160^SER 163^ASP 201^LYS 213^LEU 217^THR 227^ASP

5.1.1.1

alanine metabolic process
peptidoglycan biosynthetic process

isomerase activity
alanine racemase activity
catalytic activity
pyridoxal phosphate binding

1sv2B

[pdb]

1.32123
0.00363456

6^LEU 36^ASP 40^THR 45^GLU 70^ARG 137^LYS

3.5.1.88

metal ion binding
hydrolase activity
iron ion binding
peptide deformylase activity

translation

2z63A

[pdb]

1.32168
0.00363464

241^ASN 264^ARG 294^ASP 319^THR 321^GLU 337^LEU

external side of plasma membrane
integral to plasma membrane
perinuclear region of cytoplasm
lipopolysaccharide receptor complex
membrane
integral to membrane
plasma membrane
intrinsic to membrane

lipopolysaccharide receptor activity
lipopolysaccharide binding
transmembrane receptor activity
receptor activity
protein binding
receptor activity
protein binding

positive regulation of platelet activation
response to lipopolysaccharide
detection of lipopolysaccharide
defense response to Gram-negative bacterium
positive regulation of interleukin-8 biosynthetic process
positive regulation of tumor necrosis factor biosynthetic process
positive regulation of interleukin-12 biosynthetic process
detection of fungus
macrophage activation
negative regulation of osteoclast differentiation
T-helper 1 type immune response
innate immune response
immune response
inflammatory response
I-kappaB kinase/NF-kappaB cascade
signal transduction
positive regulation of JNK cascade
positive regulation of I-kappaB kinase/NF-kappaB cascade
positive regulation of tumor necrosis factor production
response to bacterium
production of nitric oxide during acute inflammatory response

2a85A

[pdb]

1.32257
0.00363482

13^LYS 75^LEU 317^ARG 324^GLU 327^THR 332^ASP

1.1.99.31

membrane
peroxisome

oxidation reduction
aromatic compound catabolic process
mandelate metabolic process
metabolic process
oxidation reduction
oxidative photosynthetic carbon pathway
photorespiration
metabolic process

oxidoreductase activity
(S)-mandelate dehydrogenase activity
FMN binding
electron carrier activity
catalytic activity
oxidoreductase activity
(S)-2-hydroxy-acid oxidase activity
FMN binding
electron carrier activity
catalytic activity

2zhcA

[pdb]

1.32626
0.00383106

170^ASP 175^THR 194^ASP 201^LEU 291^LYS 307^SER

plasmid partitioning

2p3pB

[pdb]

1.32738
0.00383129

89^ARG 130^SER 134^GLU 153^THR 165^ASP 216^LEU

0.0.0.0

1wppB

[pdb]

1.32775
0.00383137

15^ASP 45^GLU 47^THR 53^TYR 123^SER 156^LYS

3.6.1.1

cytoplasm

metal ion binding
manganese ion binding
hydrolase activity
pyrophosphatase activity
inorganic diphosphatase activity

2rjqA

[pdb]

1.33333
0.00404025

290^TYR 485^GLU 490^THR 492^ASP 506^SER 516^ARG

0.0.0.0

metal ion binding
hydrolase activity
zinc ion binding
metallopeptidase activity
peptidase activity
integrin binding
metalloendopeptidase activity

plasma membrane
cytoplasm
nucleus
proteinaceous extracellular matrix
extracellular region
extracellular matrix

proteolysis

2yz2A

[pdb]

1.33548
0.00404073

34^GLU 70^ARG 78^ARG 158^ASP 190^THR 193^LEU

hydrolase activity
ATP binding
nucleotide binding
nucleoside-triphosphatase activity
ATPase activity

plasma membrane
membrane

transport

1iwpA

[pdb]

1.33696
0.00404106

138^ARG 289^LYS 333^SER 359^ASP 509^LEU 521^ASP

0.0.0.0

lyase activity
glycerol dehydratase activity
lyase activity
glycerol dehydratase activity
cobalamin binding
hydro-lyase activity
catalytic activity
lyase activity
glycerol dehydratase activity

metabolic process

3d2qD

[pdb]

1.34056
0.00426252

183^GLU 192^ASN 201^ARG 212^ASP 217^THR 236^TYR

0.0.0.0

cytoplasm
nucleus

double-stranded RNA binding
metal ion binding
zinc ion binding
RNA binding
nucleic acid binding

nervous system development
myoblast differentiation
muscle organ development
embryonic limb morphogenesis
in utero embryonic development

1oyjC

[pdb]

1.34115
0.00426266

110^TYR 139^GLU 143^THR 145^GLU 151^ARG 199^ARG

2.5.1.18

transferase activity
glutathione transferase activity
transferase activity
glutathione transferase activity

1nktB

[pdb]

1.34544
0.00449794

431^GLN 468^GLU 492^THR 493^ASP 503^LEU 573^ARG

ATP binding
nucleotide binding
protein binding

intracellular protein transmembrane transport
protein transport
transport
protein import
intracellular protein transport
protein targeting

plasma membrane
cytoplasm
membrane

1u79B

[pdb]

1.34631
0.00449815

14^LEU 18^ASP 34^LYS 49^SER 90^THR 122^ASP

5.2.1.8

chloroplast
thylakoid lumen
plastid
chloroplast thylakoid lumen
thylakoid

peptidyl-prolyl cis-trans isomerase activity
isomerase activity

protein folding

1ud9A

[pdb]

1.34623
0.00449813

30^LYS 77^LEU 86^GLU 90^ASP 93^SER 100^THR

DNA binding
DNA polymerase processivity factor activity

DNA replication
regulation of DNA replication

PCNA complex

3f4lD

[pdb]

1.34629
0.00449815

154^ASP 173^TYR 196^ASP 209^THR 220^LYS 339^SER

oxidation reduction
metabolic process

oxidoreductase activity
electron carrier activity
binding
catalytic activity
protein binding

1ka9F

[pdb]

1.34688
0.00449829

105^SER 131^ASP 160^LYS 172^THR 184^ASP 223^LEU

cellular amino acid biosynthetic process
histidine biosynthetic process
metabolic process
cellular amino acid biosynthetic process
glutamine metabolic process
histidine biosynthetic process

cytoplasm
imidazoleglycerol-phosphate synthase complex
cytoplasm

protein binding
imidazoleglycerol-phosphate synthase activity
lyase activity
catalytic activity
imidazoleglycerol-phosphate synthase activity
transferase activity
transferase activity
transferring pentosyl groups
catalytic activity
protein binding

1mppA

[pdb]

1.34769
0.00449849

37^ASP 54^ARG 61^SER 69^TYR 87^ASP 100^THR

3.4.23.23

hydrolase activity
peptidase activity
aspartic-type endopeptidase activity

proteolysis

1vgvC

[pdb]

1.35071
0.00449922

117^GLU 135^ARG 154^GLN 172^THR 358^ASP 366^LEU

5.1.3.14

cytoplasm

entry of virus into host cell
detection of virus
lipopolysaccharide biosynthetic process
UDP-N-acetylglucosamine metabolic process

isomerase activity
UDP-N-acetylglucosamine 2-epimerase activity

1md9A

[pdb]

1.35149
0.00474071

190^SER 209^TYR 309^LYS 334^GLU 361^ASP 388^THR

cytoplasm

ligase activity
ATP binding
nucleotide binding
(2,3-dihydroxybenzoyl)adenylate synthase activity
catalytic activity

metabolic process
siderophore biosynthetic process

1jymB

[pdb]

1.3533
0.00474117

66^LYS 77^ARG 80^GLU 82^THR 85^ASP 174^TYR

0.0.0.0

hydrolase activity
formylmethionine deformylase activity
peptide deformylase activity
iron ion binding

translation

1qjqA

[pdb]

1.35729
0.00474217

72^TYR 167^LYS 630^ASP 645^THR 670^ASP 715^ARG

cell outer membrane
integral to membrane
membrane
plasma membrane

entry of virus into host cell
detection of virus
iron ion transport
ion transport
transport
siderophore transport

iron ion binding
receptor activity
siderophore-iron transmembrane transporter activity
transporter activity

2w4mA

[pdb]

1.35762
0.00474225

16^THR 19^ASP 53^GLN 104^ARG 130^LEU 189^ASP

3.1.3.29

N-acetylneuraminate biosynthetic process
carbohydrate metabolic process
metabolic process

N-acylneuraminate-9-phosphatase activity
hydrolase activity
phosphoglycolate phosphatase activity
catalytic activity
magnesium ion binding

cellular_component

1ia6A

[pdb]

1.35834
0.00474243

67^GLN 208^SER 253^THR 258^ASP 265^LEU 313^GLU

0.0.0.0

carbohydrate metabolic process
polysaccharide catabolic process

hydrolase activity
hydrolyzing O-glycosyl compounds
catalytic activity

1k9tA

[pdb]

1.35953
0.00499141

187^LEU 225^LYS 278^SER 313^ASP 358^GLU 360^THR

3.2.1.14

cation binding
chitinase activity
hydrolase activity
hydrolyzing O-glycosyl compounds
catalytic activity
hydrolase activity
acting on glycosyl bonds
hydrolase activity
chitinase activity
cation binding
hydrolase activity
hydrolyzing O-glycosyl compounds
catalytic activity
hydrolase activity
hydrolase activity
acting on glycosyl bonds

chitin catabolic process
carbohydrate metabolic process
metabolic process
chitin catabolic process
carbohydrate metabolic process
polysaccharide catabolic process
metabolic process

1pm2B

[pdb]

1.35957
0.00499142

44^LEU 89^ARG 103^GLU 106^THR 109^GLU 201^ASN

1.17.4.1

cytosol

metal ion binding
oxidoreductase activity
ribonucleoside-diphosphate reductase activity
transition metal ion binding
protein binding
iron ion binding

oxidation reduction
DNA replication
deoxyribonucleoside diphosphate metabolic process

1bjnB

[pdb]

1.36384
0.00499256

122^LYS 160^ASP 162^THR 164^ASP 189^TYR 296^SER

2.6.1.52

cellular amino acid biosynthetic process
pyridoxine biosynthetic process
L-serine biosynthetic process
metabolic process

cytoplasm

transferase activity
transaminase activity
O-phospho-L-serine:2-oxoglutarate aminotransferase activity
pyridoxal phosphate binding
catalytic activity
protein binding

2nn6C

[pdb]

1.36654
0.00525689

90^VAL 103^ILE 145^THR 209^PRO 211^HIS 217^ILE

exosome (RNase complex)
nucleolus
nucleus
nucleolus
cytoplasm
nucleus
exosome (RNase complex)
cytoplasm
nucleus
exosome (RNase complex)
cellular_component
cytoplasm
nucleus
exosome (RNase complex)
nucleolus
nucleolus
nucleolus
nucleolus
nucleolus
exosome (RNase complex)
nucleus
cytoplasm
nucleolus
nucleus
exosome (RNase complex)
nuclear exosome (RNase complex)
cytoplasm
nucleus
exosome (RNase complex)
nucleolus
cytoplasmic exosome (RNase complex)
nuclear exosome (RNase complex)
cytoplasm
nucleus
exosome (RNase complex)
cytoplasm
nucleus
exosome (RNase complex)

protein binding
RNA binding
hydrolase activity
exonuclease activity
nuclease activity
protein binding
3'-5'-exoribonuclease activity
hydrolase activity
exonuclease activity
nuclease activity
RNA binding
hydrolase activity
exonuclease activity
nuclease activity
RNA binding
7S RNA binding
3'-5'-exoribonuclease activity
protein binding
molecular_function
hydrolase activity
exonuclease activity
nuclease activity
RNA binding
3'-5'-exoribonuclease activity
identical protein binding
protein binding
protein binding
RNA binding
3'-5'-exoribonuclease activity
hydrolase activity
exonuclease activity
nuclease activity
3'-5'-exoribonuclease activity
hydrolase activity
exonuclease activity
nuclease activity
RNA binding
protein binding
RNA binding
3'-5'-exoribonuclease activity
hydrolase activity
exonuclease activity
nuclease activity
protein binding
3'-5'-exoribonuclease activity
hydrolase activity
exonuclease activity
nuclease activity
RNA binding
protein binding
hydrolase activity
exonuclease activity
nuclease activity
RNA binding
3'-5'-exoribonuclease activity

rRNA processing
rRNA processing
RNA processing
rRNA processing
biological_process
rRNA processing
RNA processing
RNA catabolic process
rRNA processing
RNA processing
rRNA processing
RNA processing
immune response
rRNA processing
RNA processing
rRNA processing
rRNA processing
RNA processing

1vqvB

[pdb]

1.36688
0.00525698

157^LEU 203^ASN 278^ASP 280^THR 281^GLU 284^ARG

0.0.0.0

kinase activity
thiamin phosphate kinase activity
catalytic activity

thiamin biosynthetic process